Endoplasmic reticulum (ER) News and Research

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Genetic signature predicts clinical outcomes in certain types of breast cancer

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.

19 May 2009

Urgent Care Centers: Between the ER and the family doctor

Urgent care centers (UCCs) are providing an alternative to emergency room treatment. A study published in the open access journal BMC Health Services Research has shown that UCCs tend to be open well outside of office hours and offer a wider range of services than primary care offices.

14 May 2009

San Francisco Chronicle examines emergency department HIV testing program

The San Francisco Chronicle on Monday examined an HIV testing program at San Francisco General Hospital's emergency department, which is part of a nationwide CDC program that offers routine testing to all ED patients.

12 May 2009

Loss of stromal protein major new prognostic factor in patients with breast cancer

Reporting online in the American Journal of Pathology, researchers from the Kimmel Cancer Center at Jefferson have implicated the loss of a stromal protein called caveolin-1 as a major new prognostic factor in patients with breast cancer, predicting early disease recurrence, metastasis and breast cancer patient survival.

6 May 2009

Drugs designed to tackle endoplasmic reticulum stress might be useful in treating heart disease

Researchers say they have evidence to explain what separates your average blood vessel plaque from those that are at high risk for triggering the development of dangerous - even fatal - blood clots.

5 May 2009

Level of cellular stress determines longevity of retinal cells

Stress can be adaptive. It can make you sharper, help you focus and it can even improve your performance. But too much of it can tax cells to the point where they can no longer cope and slowly self-destruct.

30 Apr 2009

New York Times examines use of message placement on TV programs

The Bill & Melinda Gates Foundation is "set to expand its involvement" with the entertainment industry and "spend more money on influencing popular culture" through a new deal with Viacom, the parent company to television networks that include MTV, VH1, Nickelodeon and BET, the New York Times reports.

5 Apr 2009

Statins reduce odds of an asthma-related hospitalization or ER visit

Results of a new study presented at the 2009 Annual Meeting of the American Academy of Asthma, Allergy and Immunology (AAAAI) show dramatic reductions in emergency room (ER) visits and hospitalizations for asthma patients taking cholesterol-lowering statins in addition to common asthma treatments.

15 Mar 2009

Racial disparities in ER length of stay point to added risks for minority patients

Sick or injured African-American patients wait about an hour longer than patients of other races before being transferred to an inpatient hospital bed following emergency room visits, according to a new national study published in the journal Academic Emergency Medicine.

5 Mar 2009

Discovery of new gene that causes Leber congenital amaurosis and retinitis pigmentosa

The team of Dr. Robert Koenekoop which includes Dr. Irma Lopez from the Research Institute of the MUHC at the Montreal Children's Hospital played a crucial role in the international collaboration that led to the discovery of a new gene that causes Leber congenital amaurosis (LCA) and retinitis pigmentosa (RP), two devastating forms of childhood blindness.

5 Mar 2009

Incidental findings during trauma evaluation - a growing concern

Nearly one-fifth of trauma patients who undergo CT evaluation have incidental findings, according to a study performed by Columbus Radiology Corp. at Grant Medical Center in Columbus, OH.

4 Mar 2009

Maine medical residents receive dental care training to address state dentist shortage

The New York Times on Tuesday examined how "[d]entists are in such short supply in Maine that primary care doctors who do their medical residency in the state are learning to lance abscesses, pull teeth and perform other basic dental skills through a program that began in 2005."

4 Mar 2009

Doors open soon at new $360 million hospital with all-private rooms

When the doors to the new Henry Ford West Bloomfield Hospital open March 15, patients, their families and the community will find a health care experience unlike any other, offering the latest in medicine, technology and patient safety, integrated with wellness and prevention programs all under one roof.

25 Feb 2009

Endo and Penwest announce settlement of Opana ER litigation

Endo Pharmaceuticals and Penwest Pharmaceuticals announced today that the companies have settled litigation with Actavis South Atlantic LLC regarding the production and sale of generic formulations of Opana(R) ER (oxymorphone hydrochloride) Extended Release Tablets CII.

22 Feb 2009

Back from the dead twice

“I died twice,” says a teary-eyed DeWayne Lark, “If I didn't believe in miracles before, I believe in them now.”

20 Feb 2009

A view into the human body: the formation of cell organelles

Scientists at the RUB publish the results of their study in the Journal of Biological Chemistry.

10 Feb 2009

Atorvastatin and lovastatin found to be ineffective for breast cancer prevention

Laboratory work in animals showed limited activity when statins were given to prevent breast cancer, according to a report in the February issue of Cancer Prevention Research , a journal of the American Association for Cancer Research.

8 Feb 2009

New test predicts how breast cancer patients respond to chemotherapy

Researchers at the Swiss Institute of Bioinformatics and the Swiss National Center of Competence in Research in Molecular Oncology in Lausanne have developed a new test to predict how breast cancer patients respond to chemotherapy, which could help change how treatment is delivered in the future.

3 Feb 2009

Study identifies potential 'safe period' for hormone replacement use

A new study makes important new findings on the role of hormone use on the risk of breast cancer, confirming that the use of estrogen plus progesterone increases the risk of both ductal and lobular breast cancer far more than estrogen-only; suggesting a two-year 'safe' period for the use of estrogen and progesterone; and finding that the increased risk for ductal cancers observed in long-term past users of hormone replacement therapy drops off substantially two years after hormone use is stopped.

2 Feb 2009

Researchers discover link between brain iron levels and serotonin

Vanderbilt University Medical Center investigators have found a surprising link between brain iron levels and serotonin, a neurotransmitter involved in neuropsychiatric conditions ranging from autism to major depression.

29 Jan 2009