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New TGT method helps detect and measure mechanics of single-molecule interaction

Cells in the human body do not function in isolation. Living cells rely on communication with their environment-neighboring cells and the surrounding matrix-to activate a wide range of cellular functions, including reproduction of new cells, differentiation of stem cells into distinct cell types, cell adhesion, and migration of white blood cells to fight bodily infections.

24 May 2013

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology.

24 May 2013

Discarded neutrophils release stem cells from bone marrow into bloodstream

CNIC researchers have discovered that the daily clearance of neutrophils from the body stimulates the release of hematopoietic stem cells from the bone marrow into the bloodstream, according to a report published today in the journal Cell.

24 May 2013

Study identifies specific genetic factors that influence occurrence and severity of sepsis

A study published in the June issue of Anesthesiology represents an important first step in establishing new therapeutic options targeting specific genetic areas that influence the occurrence and severity of sepsis - a life-threatening, whole-body response to infection.

23 May 2013

Long-term depression linked with life-threatening chronic disease, earlier death

The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain. In recent years some studies have linked major, long-term depression with life-threatening chronic disease and with earlier death, even after lifestyle risk factors have been taken into account.

23 May 2013

New research reveals how endothelium maintains highly efficient barrier function

The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely withstands blood flow, hydrostatic pressure, stretch and tissue compression to create a unique and highly dynamic barrier that maintains the organization necessary to partition tissues from the body's circulatory system.

17 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

Prostate cancer drug Xofigo gets FDA approval

The U.S. Food and Drug Administration today approved Xofigo (radium Ra 223 dichloride) to treat men with symptomatic late-stage (metastatic) castration-resistant prostate cancer that has spread to bones but not to other organs.

16 May 2013

Researchers show how cells are driven mainly by water power

Water gives life. Researchers at Linköping University in Sweden now show how the cells in our bodies are driven mainly by water power - a discovery that in the long run opens the way for a new strategy in cancer therapy.

14 May 2013

Inhibiting powerful protein with new agents may supply broad benefit for lymphoma patients

A soon-to-be-tested class of drug inhibitors were predicted to help a limited number of patients with B-cell lymphomas with mutations affecting the EZH2 protein.

14 May 2013

Annual Century for the Cure bike ride supports research on hematologic malignancies

The annual Century for the Cure bike ride that has raised more than $1 million since 2005 for research at The Cancer Institute of New Jersey is now making it possible for new scientific exploration in the area of hematologic malignancies.

14 May 2013

Scientists make novel discoveries concerning current vaccine against whooping cough

Scientists at Trinity College Dublin have made novel discoveries concerning the current vaccine against whooping cough that may lead to the development of an improved future vaccine.

13 May 2013

Gene offers new insights into treatment strategies for deep-vein thrombosis

A gene associated with both protection against bacterial infection and excessive blood clotting could offer new insights into treatment strategies for deep-vein thrombosis -- the formation of a harmful clot in a deep vein.

9 May 2013

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks an inflammatory process that fuels the buildup of artery-clogging plaque.

8 May 2013

Leukocyte News and Research

New TGT method helps detect and measure mechanics of single-molecule interaction

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Discarded neutrophils release stem cells from bone marrow into bloodstream

Study identifies specific genetic factors that influence occurrence and severity of sepsis

Long-term depression linked with life-threatening chronic disease, earlier death

New research reveals how endothelium maintains highly efficient barrier function

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Prostate cancer drug Xofigo gets FDA approval

Researchers show how cells are driven mainly by water power

Inhibiting powerful protein with new agents may supply broad benefit for lymphoma patients

Annual Century for the Cure bike ride supports research on hematologic malignancies

Scientists make novel discoveries concerning current vaccine against whooping cough

Gene offers new insights into treatment strategies for deep-vein thrombosis

New therapeutic targets for reducing heart disease in people with type 1 diabetes

Scientists spell out pivotal role of Peli1 in mouse model of multiple sclerosis

Synthetic anti-inflammatory substances related to marijuana may help fight HIV infection

Findings set the stage for identifying potential new drug targets, treatment strategies for AML

Details about genomic landscapes of AML and endometrial cancer revealed

Atopy’s immunologic properties change with age in asthma

Cell sorting device improves detection of circulating tumor cells

Immunology eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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