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Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

A vexing problem in the development of vaccines has been the need to achieve the right glycosylation profile for the viral antigens. A new study, recently released as a preprint on the bioRxiv* server, shows how a sequential cell-free approach produced complex N-glycans from simpler types, in a one-pot reaction.

4 May 2021

Arresting tumor growth for a variety of cancers through T cell engineering

Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it's possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues.

30 Apr 2021

Thousands of men to trial new home test kit for prostate cancer

Thousands of men worldwide are to receive a home test kit for prostate cancer – thanks to pioneering research from the University of East Anglia and the Norfolk and Norwich University Hospital (NNUH).

30 Apr 2021

Medicare could save nearly $500 million per year by reducing use of low-value preventive care services

A UCLA-led study shows that physicians frequently order preventive medical services for adult Medicare beneficiaries that are considered unnecessary and of "low value" by the U.S. Preventive Services Task Force - at a cost of $478 million per year.

29 Apr 2021

Study shows decline in prostate cancer diagnoses during the pandemic

During the first wave of the corona pandemic, 36 per cent fewer men were diagnosed with prostate cancer in Sweden than in previous years.

29 Apr 2021

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases, is now recruiting patients for a Phase 2 clinical trial to investigate whether pills containing white button mushroom extract could regulate the immune system, affecting prostate-specific antigen (PSA) levels to either remain stable or decline.

29 Apr 2021

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer.

29 Apr 2021

New method could be used to develop more effective treatments for cancer, metabolic disorders

Researchers from the University of Copenhagen have developed a new method that makes it possible to control human hormones and metabolism.

28 Apr 2021

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

Two members of the University of Colorado Cancer Center have received prestigious Idea Awards from the U.S. Department of Defense's Peer Reviewed Cancer Research Program.

27 Apr 2021

New urine test for prostate cancer shows aggressiveness of the disease

Researchers from the University of East Anglia have developed a new urine test for prostate cancer which also shows how aggressive the disease is.

27 Apr 2021

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

The University of Southern Denmark, Rigshospitalet and the University of Copenhagen have come together to study the effects of Football Fitness on various health parameters and self-rated health following treatment for breast cancer.

26 Apr 2021

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

The hormonal therapies used to treat many breast and prostate cancers raise the risk of a heart attack and stroke, and patients should be monitored regularly and receive treatment to reduce risk and detect problems as they occur.

26 Apr 2021

Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases

The first National Institutes of Health National Cancer Institute-funded clinical study examining stereotactic body radiotherapy (SBRT) in the treatment of oligometastatic breast, prostate, and non-small cell lung (NSCLC) cancers displayed evidence that SBRT can be safely used to treat patients who have multiple metastases.

23 Apr 2021

Contralateral esophagus sparing technique can prevent complication in lung cancer patients

For many patients with localized lung cancer (non-small-cell lung carcinoma and small cell lung carcinoma), high-dose radiation with concurrent chemotherapy is a potential cure. Yet this treatment can cause severe, acute inflammation of the esophagus (esophagitis) in about one in five patients, requiring hospitalization and placement of a feeding tube.

23 Apr 2021

Celastrol shows potential anti-SARS-CoV-2 activity

A new study published on the bioRxiv* preprint server focuses on the in-silico predictions to repurpose existing drug compounds, that may have the ability to reverse the SARS-CoV-2 gene expression induced in host cells.

23 Apr 2021

FDA approves clinical trials to test the safety of cancer-detection technology

The U.S. Food and Drug Administration has approved human clinical trials to test the safety of cancer-detection technology developed at Case Western Reserve University: a tumor-targeting contrast agent that accurately detects aggressive prostate cancer in a magnetic resonance imaging (MRI) scan.

22 Apr 2021

Henry Ford receives $250,000 grant to reduce prostate cancer disparities among Black men

Henry Ford Cancer Institute has received a $250,000 grant from Pfizer Global Medical Grants and the American Cancer Society to reduce prostate cancer disparities among Black men.

21 Apr 2021

Researchers develop a new method for the detection and evolution of kidney cancer

The research groups Mintota and Photochemistry Reactivity Group of the faculties of Chemistry and Pharmacy of the University of Valencia have developed a method for the detection and evolution of kidney cancer through urine and the dispersion of gold nanoparticles, in what is the first system that will provide reliable information on the existence and progress of this pathology.

21 Apr 2021

New efforts to improve the efficacy of nucleotide-based drugs against prostate cancer, bone metastasis

Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis.

21 Apr 2021

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Prostate News and Research

Could in vitro glycoengineering help produce better SARS-CoV-2 spike candidates for vaccine research?

Arresting tumor growth for a variety of cancers through T cell engineering

Thousands of men to trial new home test kit for prostate cancer

Medicare could save nearly $500 million per year by reducing use of low-value preventive care services

Study shows decline in prostate cancer diagnoses during the pandemic

City of Hope initiates Phase 2 clinical trial to investigate if mushroom tablets could slow prostate cancer

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

New method could be used to develop more effective treatments for cancer, metabolic disorders

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

New urine test for prostate cancer shows aggressiveness of the disease

Football Fitness improves balance, muscle strength and bone density in women treated for breast cancer

Hormonal therapies for breast and prostate cancers increase the risk of heart attack, stroke

Study: Stereotactic body radiotherapy can be safely used to treat patients with multiple metastases

Contralateral esophagus sparing technique can prevent complication in lung cancer patients

Celastrol shows potential anti-SARS-CoV-2 activity

FDA approves clinical trials to test the safety of cancer-detection technology

Henry Ford receives $250,000 grant to reduce prostate cancer disparities among Black men

Researchers develop a new method for the detection and evolution of kidney cancer

New efforts to improve the efficacy of nucleotide-based drugs against prostate cancer, bone metastasis

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

What to know about prostate cancer eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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