Efficacy News and Research

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Study provides support for new understanding of the immune system

A study published in the journal Science provides support for a new-and still controversial-understanding of the immune system. The research was conducted by collaborators in the U.S. and Europe, including Robert Cramer, PhD, an assistant professor of microbiology and immunology at the Geisel School of Medicine and member of the Dartmouth Lung Biology Center, and Kelly Shepherdson, PhD, at the time a graduate student in Cramer's lab.

29 Sep 2014

Study demonstrates longer-term benefits of Lung Flute for COPD patients

Patients with chronic obstructive pulmonary disease (COPD) report improved symptoms and health status when they use a hand-held respiratory device called the Lung Flute-, according to a new study by the University at Buffalo. Usually caused by smoking, COPD, which includes chronic bronchitis and emphysema, is the third leading cause of death in the U.S.

29 Sep 2014

Oral afatinib significantly improves progression-free survival in patients with head and neck cancer

The tyrosine kinase inhibitor afatinib significantly improved progression-free survival compared to methotrexate in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after failure of platinum-based chemotherapy, the results of a phase III trial show.

29 Sep 2014

Anamorelin drug safe and well tolerated in advanced non-small cell lung cancer, Phase III trial reveals

A new drug, anamorelin, improves appetite and body mass in patients with advanced lung cancer who are suffering cancer anorexia and cachexia, according to phase III data presented at the ESMO 2014 Congress in Madrid, Spain.

29 Sep 2014

Fecal occult blood screening increases diagnosis rate of high-risk polyps by 89%

The introduction of biennial colorectal cancer screening in a region of France increased the rate of diagnosis of high risk pre-cancerous adenomas (sometimes called polyps) by 89%, researchers have reported at the ESMO 2014 Congress in Madrid.

29 Sep 2014

Access to potentially life-extending cancer drugs varies worldwide

Access to potentially life-extending cancer drugs varies significantly in different regions of the world, two new studies show at the ESMO 2014 Congress in Madrid, Spain.

26 Sep 2014

Thirteen research projects to explore nondrug approaches to manage pain, other health conditions

Thirteen research projects totaling approximately $21.7 million over 5 years will explore nondrug approaches to managing pain and related health conditions such as post-traumatic stress disorder (PTSD), drug abuse, and sleep issues. The effort seeks to enhance options for the management of pain and associated problems in U.S. military personnel, veterans, and their families.

26 Sep 2014

CorMedix submits IND application to FDA for Neutrolin

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiac, renal and infectious disease, is pleased to announce that an Investigational New Drug application (IND) for Neutrolin was submitted to the United States Food and Drug Administration on Wednesday, September 24, 2014.

25 Sep 2014

NCCN ORP awards four research grants to advance development of nintedanib

The National Comprehensive Cancer Network Oncology Research Program has awarded four grants to investigators to evaluate and define the clinical effectiveness of the investigational compound nintedanib (BIBF 1120) in non-small cell lung, colorectal, and gastrointestinal cancers.

25 Sep 2014

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

With a new $5.8 million, three-year award from the National Institutes of Health, researchers at the University of Pittsburgh School of Medicine will further develop a state-of-the-art, microfluidic 3D model system that mimics structure and function of the liver to better predict organ physiology, assess drug toxicity and build disease models.

25 Sep 2014

ECT benefits demonstrated in randomised controlled trial

Electroconvulsive therapy is more effective than pharmacological treatment for the reduction of depressive symptoms in patients with treatment-resistant bipolar depression, Norwegian study data show.

24 Sep 2014

Chemotherapy may benefit advanced pulmonary carcinoid tumour patients

A review of patients with advanced pulmonary carcinoid tumours shows that they can be responsive to chemotherapy.

24 Sep 2014

Antacids linked to reduced erlotinib efficacy

Acid suppression therapy may negatively impact outcome among patients receiving erlotinib for advanced non-small-cell lung cancer, Canadian study findings show.

24 Sep 2014

Alectinib promise for crizotinib-resistant NSCLC

Alectinib has shown promising antitumour activity in patients with ALK-rearranged non-small-cell lung cancer that is resistant to crizotinib, researchers report.

23 Sep 2014

C Diff Foundation to present 2014 "Raising C.difficile Awareness" conference in November

C Diff Foundation is proud to present the 2014 "Raising C.difficile Awareness" conference. Join us November 4th at 8 a.m. – 5 p.m. at the University of Illinois at Chicago, Student Center, West 828 S. Wolcott Avenue, Thompson Room, Chicago, IL.

23 Sep 2014

New Jersey physician offers FDA-approved non-invasive fat reduction treatment

Arthur W. Perry, MD, FACS, a New Jersey based board-certified plastic surgeon, is the first physician in the Central New Jersey region to offer UltraShape™, a revolutionary treatment recently FDA cleared for Fat Cell Destruction.

23 Sep 2014

Promising new approach for combating colorectal cancer

Scientists at the University of York are working on a promising new approach for tackling colorectal cancer, the second most common cause of cancer-related death.

23 Sep 2014

Distinct patterns of gene expression identified in several groups of pancreatic CTCs

Analysis of circulating tumor cells (CTCs) in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases.

23 Sep 2014

TauRx achieves target enrolment in second LMTX Phase III clinical trial for Alzheimer's disease

TauRx Therapeutics Ltd has achieved its target enrolment of 700 subjects with mild Alzheimer's disease into the second of its two Phase III clinical trials of LMTX, a tau aggregation inhibitor, for the treatment of Alzheimer's disease.

22 Sep 2014

Phase IIa clinical trial data of ATL1102 in MS patients published in journal Neurology

Antisense Therapeutics is pleased to report the publication of previously generated Phase IIa clinical trial data on ATL1102 in the medical journal Neurology.

22 Sep 2014

Efficacy News and Research

Study provides support for new understanding of the immune system

Study demonstrates longer-term benefits of Lung Flute for COPD patients

Oral afatinib significantly improves progression-free survival in patients with head and neck cancer

Anamorelin drug safe and well tolerated in advanced non-small cell lung cancer, Phase III trial reveals

Fecal occult blood screening increases diagnosis rate of high-risk polyps by 89%

Access to potentially life-extending cancer drugs varies worldwide

Thirteen research projects to explore nondrug approaches to manage pain, other health conditions

CorMedix submits IND application to FDA for Neutrolin

NCCN ORP awards four research grants to advance development of nintedanib

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

ECT benefits demonstrated in randomised controlled trial

Chemotherapy may benefit advanced pulmonary carcinoid tumour patients

Antacids linked to reduced erlotinib efficacy

Alectinib promise for crizotinib-resistant NSCLC

C Diff Foundation to present 2014 "Raising C.difficile Awareness" conference in November

New Jersey physician offers FDA-approved non-invasive fat reduction treatment

Promising new approach for combating colorectal cancer

Distinct patterns of gene expression identified in several groups of pancreatic CTCs

TauRx achieves target enrolment in second LMTX Phase III clinical trial for Alzheimer's disease

Phase IIa clinical trial data of ATL1102 in MS patients published in journal Neurology

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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