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Biological therapy may decrease the risk of severe COVID-19

A recent observational study by Spanish researchers, currently available on the medRxiv preprint server, suggests that patients with immune-mediated diseases who receive biological therapy may have a lower risk for severe manifestations of coronavirus disease (COVID-19).

25 Jun 2020

Global research community revises WHO COVID-19 research priorities

Researchers have described the results of a survey aiming to determine the current applicability of the World Health Organization’s COVID-19 Research Roadmap and whether there are new priorities that should be focused on at this point in time during the pandemic.

25 Jun 2020

Superbug hijacks the wound healing system to cause serious and persistent disease

Monash University researchers have discovered that the devastating bacterial superbug Clostridioides difficile hijacks the human wound healing system in order to cause serious and persistent disease, opening up the development of new therapies to treat the disease.

25 Jun 2020

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the last 15 years by identifying drivers of cancer at the molecular level.

25 Jun 2020

Black patients with esophageal cancer less likely to receive surgery for early-stage disease

Black patients with esophageal cancer are at a higher risk of death compared to white patients. Although many reasons have been suggested for this, few have given physician actionable information.

25 Jun 2020

Scientists pinpoint mutations that increase bacterial deadliness

As far as humans are concerned, bacteria can be classified as either harmful, pathogenic bacteria and harmless or beneficial non-pathogenic bacteria.

25 Jun 2020

Scientists study how magnetic nanoparticles affect cancer cells in the liver

Scientists from the Immanuel Kant Baltic Federal University (IKBFU) and National University of Science and Technology "MISiS" have studied how magnet nanoparticles affect cancer cells in the human liver.

25 Jun 2020

Research team solves 40-year old mystery in leukemia treatment

A research team led by the University of Kent and Goethe-University Frankfurt am Main, has solved an almost 40-year old mystery in leukemia therapy and the drug nelarabine.

25 Jun 2020

Researchers develop gold nanoparticles to reduce neuronal cell death

Gold nanoparticles have been developed in the laboratory in order to reduce the cell death of neurons exposed to overexcitement.

25 Jun 2020

Nurse-guided Internet-delivered CBT-I may help treat insomnia

Guidelines recommend cognitive behavioral therapy for insomnia (CBT-I) as the first line of treatment for insomnia in general practice, but CBT-I is rarely available.

25 Jun 2020

Fearing the deadly combo of COVID-19 and cancer

Three Tuesdays each month, Katherine O'Brien straps on her face mask and journeys about half an hour by Metra rail to Northwestern University's Lurie Cancer Center.

25 Jun 2020

Berkeley Lights announces Opto™ antigen-presenting bead kit to accelerate the expansion of antigen-specific T cells used to develop cell-based therapies

Berkeley Lights, Inc. today announced the Opto Antigen-Presenting Bead kit, a new reagent kit that activates and expands antigen-specific T cells in blood.

From Bruker Cellular Analysis 25 Jun 2020

Study assesses impact of anti-SARS-CoV-2 convalescent plasma in COVID-19 disease

The current COVID-19 pandemic is still very much active in most parts of the world. In the absence of effective antiviral drugs or vaccines, scientists are studying the use of blood plasma from convalescent COVID-19 patients, banking on its neutralizing antibody content.

25 Jun 2020

New therapeutic approach for Parkinson’s and other neurodegenerative diseases

Xiang-Dong Fu, PhD, has never been more excited about something in his entire career. He has long studied the basic biology of RNA, a genetic cousin of DNA, and the proteins that bind it. But a single discovery has launched Fu into a completely new field: neuroscience.

25 Jun 2020

Platelets may be contributing to COVID-19

The current pandemic of COVID-19 is characterized mainly by severe acute respiratory distress of the lungs, but other organ dysfunctions are also being observed, including the heart and blood vessels. Now, a new paper published on the preprint server medRxiv* in June 2020 describes the abnormal activation of platelets in this disease and the link between this phenomenon and poor outcomes for COVID-19 patients.

24 Jun 2020

Study examines statin use among nursing home residents nearing the end of life

Cardiovascular disease (also called heart disease) is one of the most common medical conditions older adults face. In nursing homes, almost half of all older adult residents have been diagnosed with problems affecting the heart and/or blood vessels.

24 Jun 2020

PCOS subtypes associated with distinct genetic variations, finds study

Researchers working on a National Institutes of Health (NIH) funded study found that polycystic ovary syndrome (PCOS) has distinct subtypes that are associated with genetic variations.

24 Jun 2020

Structured 'cut-and-paste' design enables streamlined development of SARS-CoV-2 molecular probes

A seminal study by US researchers, currently available on the bioRxiv* preprint server, demonstrates how structure-based design can be efficiently employed to develop molecular probes targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike and its domains, with possible future use in diagnostics, treatment and vaccine development.

24 Jun 2020

Common cancer treatments do not worsen COVID-19 infection, study finds

The characterization of COVID-19 in patients with cancer remains limited in published studies and nationwide surveillance analyses.

24 Jun 2020

Bacteriophage could help decrease mortality of patients with COVID-19

Bacteriophage can reduce bacterial growth in the lungs, limiting fluid build-up. This could decrease the mortality of patients affected by COVID-19, according to the peer-reviewed journal PHAGE: Therapy, Applications, and Research.

24 Jun 2020