Genes News and Research

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Gene targets for triple negative breast cancers resistant to chemotherapy found

Researchers have finally found the genetic targets that could be used for treatment and development of new drugs in patients who are resistant to chemotherapy. These patients who are resistant to chemotherapy are most likely to have triple negative breast cancer which is the most aggressive form of breast cancer. The study appeared in the latest issue of the journal Cell Metabolism.

4 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

Researchers test new strategy to increase effectiveness of topical anesthesia used in dentistry

Researchers from Brazil and Texas have started testing on humans a new strategy to increase the effectiveness of topical anesthesia used in dentistry, used by dentists to reduce patient discomfort during the application of injected anesthesia - required for more invasive procedures such as fillings, tooth extraction or surgery.

4 Oct 2017

Scientists awarded $1.3 million grant to study relationship between traumatic brain injury and dementia

The U.S. Department of Defense has awarded a team of scientists and physicians from leading health care institutions across Phoenix a $1.3 million grant over three years to study traumatic brain injury and its relationship to dementia.

4 Oct 2017

Researchers awarded NIH grant to develop, test new drugs for treating Giardia infections

The microscopic parasite Giardia can be found within Idaho, every region of the U.S. and around the world. While Giardia is not considered fatal, anyone who has suffered from the diarrheal disease knows how uncomfortable it can be.

3 Oct 2017

Scientists unravel mechanism that links gut bacteria to hypertension

One in three American adults suffers from high blood pressure, or hypertension. The disease can be passed down in families, and certain lifestyle factors such as smoking, high-sodium diets, and stress can increase the risk.

3 Oct 2017

Research uncovers potential targets for treatment of triple negative breast cancer

Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.

3 Oct 2017

Researchers identify new cancer-causing pathway behind most aggressive type of leukemia

A team led by Massachusetts General Hospital (MGH) investigators has identified a new cancer-causing pathway behind most cases of an aggressive type of leukemia, findings that could lead to new targeted treatment approaches.

3 Oct 2017

Researchers discover circadian clock at work in our muscles

Biological clocks are ticking everywhere throughout our body. They trigger the release of the hormone melatonin during sleep, favour the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day.

3 Oct 2017

Rapid, sensitive genetic test successfully detects some aggressive types of pancreatic cancer

A genetic test developed at UPMC proved highly sensitive at determining which pancreatic cysts are most likely to be associated with one of the most aggressive types of pancreatic cancer, UPMC and University of Pittsburgh School of Medicine scientists reported in Gut, the journal of the British Society of Gastroenterology.

3 Oct 2017

Liquid biopsy can reveal response to checkpoint inhibitor-based immunotherapies

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.

3 Oct 2017

Alterations in circulating tumor DNA associated with response to checkpoint inhibitors

The number of alterations detected in the DNA collected from blood samples (liquid biopsies) of cancer patients treated with immune checkpoint inhibitors was associated with response to the treatment.

3 Oct 2017

“Chemical surgery” on embryos to free them of a gene causing thalassemia

A team of Chinese researchers have for the first time “mended” defective embryos using chemical surgery to free them of a faulty gene that leads to beta thalassemia. Until now this defect was found to be incorrigible caused due to a single misspelling in the DNA code. Beta thalassemia is a dreaded blood disorder wherein the child is unable to make healthy blood needing blood transfusions on a regular basis. The study was published this week in the journal Protein and Cell.

2 Oct 2017

Benefits of Biomarkers in Colorectal Cancer Treatment

Biomarkers fall into different categories: diagnostic biomarkers, are used to identify a disease; prognostic biomarkers, help clinicians to determine, for example, whether you're more likely to die or have problems with a disease; and there are some that can be used to inform treatment, to determine whether one therapy would be more successful than another.

2 Oct 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017

TSRI scientists developed new strategy to discover novel anti-cancer therapies

Scientists at The Scripps Research Institute (TSRI) have developed and demonstrated a promising new strategy for the discovery of novel anti-cancer therapies.

30 Sep 2017

Biochemists discover genes that determine animal complexity

Genes which determine animal complexity – or what makes humans so much more complex than a fruit fly or a sea urchin – have been identified for the first time.

30 Sep 2017

Impairing critical partnership between brain cells can lead to Alzheimer's disease

Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration. The study published in Cell Metabolism reports a mechanism by which two types of brain cells, neurons and glia, normally support each other's functions.

30 Sep 2017

Northumbria researcher develops new, faster and safer way to diagnose Ebola virus

A new, faster and safer way of diagnosing the Ebola virus has been developed by an academic from Northumbria University, Newcastle.

28 Sep 2017

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

Osaka Researchers, in partnership with other Japanese and U.S. scientists, report a new gene target, KPNB1, for treatment against epithelial ovarian cancer (EOC).

28 Sep 2017

Genes News and Research

Gene targets for triple negative breast cancers resistant to chemotherapy found

Scientists manipulate living cells to produce fluorinated bioplastics

Researchers test new strategy to increase effectiveness of topical anesthesia used in dentistry

Scientists awarded $1.3 million grant to study relationship between traumatic brain injury and dementia

Researchers awarded NIH grant to develop, test new drugs for treating Giardia infections

Scientists unravel mechanism that links gut bacteria to hypertension

Research uncovers potential targets for treatment of triple negative breast cancer

Researchers identify new cancer-causing pathway behind most aggressive type of leukemia

Researchers discover circadian clock at work in our muscles

Rapid, sensitive genetic test successfully detects some aggressive types of pancreatic cancer

Liquid biopsy can reveal response to checkpoint inhibitor-based immunotherapies

Alterations in circulating tumor DNA associated with response to checkpoint inhibitors

“Chemical surgery” on embryos to free them of a gene causing thalassemia

Benefits of Biomarkers in Colorectal Cancer Treatment

Researchers produce fluorinated molecules in living cells

TSRI scientists developed new strategy to discover novel anti-cancer therapies

Biochemists discover genes that determine animal complexity

Impairing critical partnership between brain cells can lead to Alzheimer's disease

Northumbria researcher develops new, faster and safer way to diagnose Ebola virus

Drug approved to treat parasitic infections also exerts anti-tumor effect on EOC cells

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