Immune System News and Research

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Vanderbilt expert offers tips for preventing and treating poison ivy

It's the time of year when backyards attract children, trails beckon hikers, and poison ivy attacks the unwary. This itch-causing plant pest, along with its cohorts poison oak and poison sumac, cause more common allergic reactions than any other source, said Renee Miller, R.N., a certified specialist in poison information at the Tennessee Poison Center at Vanderbilt University Medical Center.

4 Jun 2015

Mary's Place by the Sea - helping women with cancer

Mary’s Place by the Sea is a respite home for women who are receiving treatment for cancer or within one year of post-cancer treatment. They provide services that complement their medical treatment, including oncology massages, individual counseling and nutrition education...

3 Jun 2015

Study: Intravenous nutrition source may significantly reduce toxicity of platinum-based cancer drugs

A single dose of an FDA-approved intravenous nutrition source may be able to significantly reduce the toxicity and increase the bioavailability of platinum-based cancer drugs, according to a study by Carnegie Mellon University biologists published in Scientific Reports.

3 Jun 2015

New article published in Spanish Journal of Pathology highlights a rare case of Hodgkin's lymphoma

Dr. Jerónimo Forteza, Professor of Pathology and Director of the Valencian Institute of Pathology, Catholic University of Valencia "San Vicente Mártir," recently published an article in the Spanish Journal of Pathology on the case of a patient with Hodgkin's lymphoma. Medicine student Pablo Sánchez Vela performed this diagnostic work under the supervision of Dr. Forteza.

3 Jun 2015

Research finding could explain why HIV envelope protein has a long tail

Virologists at Emory University School of Medicine, Yerkes National Primate Research Center, and Children's Healthcare of Atlanta have uncovered a critical detail explaining how HIV assembles its infectious yet stealthy clothing.

3 Jun 2015

National Psoriasis Foundation awards grants to support psoriatic disease research

The National Psoriasis Foundation awarded eight researchers each a one-year, $75,000 Discovery Grant to support the advancement of psoriatic disease research. By gaining a better understanding of the fundamentals of psoriatic disease--what causes psoriasis and psoriatic arthritis and what happens in the body when these diseases are present--scientists can work on better treatments and a cure.

3 Jun 2015

Researchers discover new pathway that may be vital for understanding allergic asthma

Researchers at the Centenary Institute have discovered a new pathway that may be vital for our understanding allergic asthma, the most common form of asthma and the prevalent form of childhood-onset asthma affecting 2 million Australians.

3 Jun 2015

Childhood trauma increases vulnerability to different health problems in later life

Long-term changes in immune function caused by childhood trauma could explain increased vulnerability to a range of health problems in later life, according to new research by the Institute of Psychiatry, Psychology & Neuroscience at King's College London and the NIHR Maudsley BRC.

3 Jun 2015

Nivolumab and pembrolizumab therapies continue to show promise against advanced melanomas

Results of two clinical trials reported at the American Society for Clinical Oncology Annual Meeting 2015 show continued promise of immune therapies nivolumab and pembrolizumab against advanced melanomas, specifically in the context of PD1 signaling that some tumors use to avoid immune system attack. Dr. Rene Gonzalez, MD, investigator at the University of Colorado Cancer Center and director of the Melanoma Research Clinics at the CU School of Health, is an author of both studies.

2 Jun 2015

New finding may lead to development of immunity-based therapies for tuberculosis

A study by researchers at UT Southwestern Medical Center has identified how an enzyme involved in protecting the body from pathogens senses Mycobacterium tuberculosis (TB), a bacterial pathogen that infects millions of people worldwide and causes about 1.5 million deaths annually.

2 Jun 2015

Celldex’s lead program RINTEGA demonstrates overall survival benefit in patients with recurrent glioblastoma

Celldex Therapeutics, Inc. today presented positive results from the Company’s randomized, double‐blind Phase 2 study of RINTEGA (rindopepimut) in patients with EGFRvIII‐positive, recurrent glioblastoma at the 2015 American Society of Clinical Oncology in Chicago.

2 Jun 2015

NW Bio releases promising new data on DCVax-Direct Phase I trial for inoperable solid tumors

Northwest Biotherapeutics, a U.S. biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, over the weekend in Chicago released promising new data on their Phase I trial of DCVax-Direct for direct injection into all types of inoperable solid tumors.

2 Jun 2015

MedImmune, AstraZeneca present encouraging results from new combination-focused immuno-oncology portfolio at ASCO 2015

AstraZeneca and MedImmune, the company’s global biologics research and development arm, today presented encouraging results from their novel combination-focused immuno-oncology portfolio at the American Society of Clinical Oncology (ASCO) Annual Meeting 2015.

2 Jun 2015

AstraZeneca announces efficacy and safety data for AZD9291 in first-line treatment of EGFRm advanced NSCLC

AstraZeneca today announced preliminary efficacy and safety data for AZD9291 in the first-line treatment of epidermal growth factor receptor mutation positive (EGFRm) advanced non-small cell lung cancer (NSCLC).

2 Jun 2015

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015

Green Cross Biotherapeutics starts construction on new biopharmaceutical facility in Montreal

This is with great pride that Green Cross Biotherapeutics Inc. kicked off construction today on its biopharmaceutical facility that will be located on the Montreal Technoparc's Saint-Laurent Campus. The CA$315 million project represents one of the largest green field investment projects in Canada in the biopharmaceutical industry, giving place to the construction of the first intravenous immunoglobulin (IVIG) and albumin manufacturing plant in Canada.

2 Jun 2015

Talimogene laherparepvec treatment shows durable clinical responses in advanced-stage melanoma patients

Research led by Howard L. Kaufman, MD, FACS, associate director for clinical science and chief surgical officer at Rutgers Cancer Institute of New Jersey and colleagues, shows advanced-stage melanoma patients have significant improvement in durable response rate and a trend toward improved survival when treated with a genetically-modified form of a herpes virus, whose native form causes the common cold sore.

2 Jun 2015

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers (H. pylori bacteria).

2 Jun 2015

Adaptimmune presents clinical results of NY-ESO TCR therapeutic candidate at ASCO 2015

Adaptimmune Therapeutics plc, a clinical stage biopharmaceutical company focused on the use of TCR engineered T-cell therapy to treat cancer, today announced a poster presentation of data on its lead clinical program, an affinity enhanced T-cell receptor (TCR) therapeutic targeting the NY-ESO-1 cancer antigen, in both solid and hematologic cancers.

2 Jun 2015

Genticel announces positive results of new multivalent HPV therapeutic vaccine based on Vaxiclase platform

Genticel, a French biotechnology company and developer of innovative immunotherapies to prevent cancers caused by the human papillomavirus (HPV), announces today positive preclinical in vivo proof of concept results of GTL002, its multivalent HPV therapeutic vaccine candidate based on the Company’s versatile Vaxiclase platform.

2 Jun 2015

Immune System News and Research

Vanderbilt expert offers tips for preventing and treating poison ivy

Mary's Place by the Sea - helping women with cancer

Study: Intravenous nutrition source may significantly reduce toxicity of platinum-based cancer drugs

New article published in Spanish Journal of Pathology highlights a rare case of Hodgkin's lymphoma

Research finding could explain why HIV envelope protein has a long tail

National Psoriasis Foundation awards grants to support psoriatic disease research

Researchers discover new pathway that may be vital for understanding allergic asthma

Childhood trauma increases vulnerability to different health problems in later life

Nivolumab and pembrolizumab therapies continue to show promise against advanced melanomas

New finding may lead to development of immunity-based therapies for tuberculosis

Celldex’s lead program RINTEGA demonstrates overall survival benefit in patients with recurrent glioblastoma

NW Bio releases promising new data on DCVax-Direct Phase I trial for inoperable solid tumors

MedImmune, AstraZeneca present encouraging results from new combination-focused immuno-oncology portfolio at ASCO 2015

AstraZeneca announces efficacy and safety data for AZD9291 in first-line treatment of EGFRm advanced NSCLC

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Green Cross Biotherapeutics starts construction on new biopharmaceutical facility in Montreal

Talimogene laherparepvec treatment shows durable clinical responses in advanced-stage melanoma patients

Chronic exposure to bacteria may lead to development of Type 2 diabetes

Adaptimmune presents clinical results of NY-ESO TCR therapeutic candidate at ASCO 2015

Genticel announces positive results of new multivalent HPV therapeutic vaccine based on Vaxiclase platform

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