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Researchers find new risk factor for early-onset dementia

Examining brain tissue from over 500 individuals in 11 countries, researchers from the University of Pennsylvania School of Medicine and the Children's Hospital of Philadelphia, and colleagues found a new risk factor for the second-most-common cause of early-onset dementia after Alzheimer's disease.

16 Feb 2010

CNRS-Institut researchers identify 'virulence factor' that inhibits host immune response

Oncogenic retroviruses are a particular family of viruses that can cause some types of cancer. Thierry Heidmann and his colleagues in the CNRS-Institut Gustave Roussy-Université Paris Sud 11 "Rétrovirus endogènes et éléments rétroïdes des eucaryotes supérieurs" Laboratory have studied these viruses. They have identified a "virulence factor" that inhibits the host immune response and allows the virus to spread throughout the body.

16 Feb 2010

Allele-specific DNA methylation a widespread phenomenon, reveals IoP study

Researchers from the Institute of Psychiatry (IoP), King's College London, have identified numerous novel regions of the genome where the chemical modifications involved in controlling gene expression are influenced by either genetic variation or the parental origin of that particular stretch of DNA. This contradicts previous assumptions that epigenetic signals are generally equal across both copies of a given region of the genome, except at a small number of known imprinted genes.

15 Feb 2010

EMBL-EBI hosts ChEMBLdb online database

ChEMBLdb, an online database of information on the properties of more than half a million drug and drug-like small molecules and their targets, has been launched.

12 Feb 2010

IBM, VLSCI scientists to use Blue Gene supercomputer to study human disease

IBM today announced a Research collaboratory in Melbourne, Australia, where scientists from the Victorian Life Sciences Computational Initiative at the University of Melbourne and the IBM Research Computational Biology Center will use high performance computing – including IBM's Blue Gene supercomputer – to study human disease.

12 Feb 2010

ASU scientists develop versatile DNA reader to unlock DNA genetic code

Arizona State University scientists have come up with a new twist in their efforts to develop a faster and cheaper way to read the DNA genetic code. They have developed the first, versatile DNA reader that can discriminate between DNA's four core chemical components⎯the key to unlocking the vital code behind human heredity and health.

12 Feb 2010

Also in global health news: N. Korea harvest; Zimbabwe’s health system; malaria parasite; training India's rural health workers; Myanmar recovery; health in Uganda

ZimOnline examines Zimbabwe's health system, which the country's health minister, Henry Madzorera, says has improved, but is still in need of additional progress.

11 Feb 2010

Fluidigm releases amplicon tagging protocol for Illumina GA II next-generation sequencer

Fluidigm Corporation today announced the release of its amplicon tagging protocol for the Illumina GA II next-generation sequencer. The 48.48 Access Array integrated fluidic circuit (IFC) allows Illumina GA II users to automatically prepare sequencing-ready libraries from 48 individual samples at a time, for as little as $7 (U.S.) per sample.

10 Feb 2010

Bombarding DNA nucleotides and mammalian meat with ‘femto-neutrons’ open new path to femtomedicine

Bombarding DNA nucleotides and mammalian meat with ‘femto-neutrons’ has opened up the path to femtomedicine, an entirely new cancer diagnostics, it was reported today at First Global Congress on NanoEngineering for Medicine and Biology in Houston, TX.

10 Feb 2010

Mapping of all fragile sites of yeast S.cerevisiae may lead to better understanding of cancer development

The research group of Dr. Fran-ois Robert, a researcher at the Institut de recherches cliniques de Montr-al (IRCM), in collaboration with the team of Dr. Daniel Durocher (Samuel Lunenfeld Research Institute and University of Toronto) accomplished a technical breakthrough: they mapped all the fragile sites of a living organism, the budding yeast Saccharomyces cerevisiae. The method used by the researchers can be applied to humans. This study has been published online today in the scientific journal Nature Structural and Molecular Biology.

10 Feb 2010

Biology of lung cancer varies by age and gender

The biology of lung cancer differs from one patient to the next, depending on age and sex, according to scientists at Duke University Medical Center. The findings may help explain why certain groups of patients do better than others, even though they appear to have the same disease.

10 Feb 2010

Autism Speaks: Ten most significant autism research achievements in 2009

Autism Speaks, the world's largest autism science and advocacy organization has released its annual list of the 10 most significant research achievements to have impacted autism during the previous year. Every year, Autism Speaks documents the progress made toward its mission to discover the causes and treatment for autism spectrum disorders, and compiles a list of the 10 most significant research achievements to have impacted autism during the previous year.

10 Feb 2010

Data provide key information about epigenetic profiles for gastric cancer

Gastric cancer, one of the most common types of cancer, is associated with high mortality rates. In the last decades, a decrease in the worldwide incidence has been observed with some changes in the therapeutic and diagnostic options.

10 Feb 2010

Researchers explore cellular networks that regulate cell morphology

Cellular imaging offers a wealth of data about how cells respond to stimuli, but harnessing this technique to study biological systems is a daunting challenge.

9 Feb 2010

Stanford researchers use DNA minicircles to induce pluripotency in stem cells from human fat

Tiny circles of DNA are the key to a new and easier way to transform stem cells from human fat into induced pluripotent stem cells for use in regenerative medicine, say scientists at the Stanford University School of Medicine. Unlike other commonly used techniques, the method, which is based on standard molecular biology practices, does not use viruses to introduce genes into the cells or permanently alter a cell's genome.

8 Feb 2010

Gene variants associated with human biological ageing identified

Scientists announced today (7 Feb) they have identified for the first time definitive variants associated with biological ageing in humans. The team analyzed more than 500,000 genetic variations across the entire human genome to identify the variants which are located near a gene called TERC.

7 Feb 2010

GIS: Tbx3 gene improves quality of stem cells reprogrammed from differentiated cells

In the 7 Feb. 2010 issue of the journal Nature, scientists at the Genome Institute of Singapore (GIS), report that a genetic molecule, called Tbx3, which is crucial for many aspects of early developmental processes in mammals, significantly improves the quality of stem cells that have been reprogrammed from differentiated cells.

7 Feb 2010

Breakthrough research could lead to new potential treatments for malaria

Groundbreaking research done at Singapore's Nanyang Technological University's (NTU) School of Biological Sciences (SBS) could lead to the development of more potent drugs or a vaccine for malaria, which is transmitted to humans by infected mosquitoes and kills up to three million people each year.

6 Feb 2010

Breakthrough discovery could help in developing a broad spectrum of antiviral drugs

Within a virus's tiny exterior is a store of energy waiting to be unleashed. When the virus encounters a host cell, this pent-up energy is released, propelling the viral DNA into the cell and turning it into a virus factory.

6 Feb 2010

Biochemists identify a critical piece in the evolutionary puzzle

Monash University biochemists have found a critical piece in the evolutionary puzzle that explains how life on Earth evolved millions of centuries ago.

6 Feb 2010

Genome News and Research

Researchers find new risk factor for early-onset dementia

CNRS-Institut researchers identify 'virulence factor' that inhibits host immune response

Allele-specific DNA methylation a widespread phenomenon, reveals IoP study

EMBL-EBI hosts ChEMBLdb online database

IBM, VLSCI scientists to use Blue Gene supercomputer to study human disease

ASU scientists develop versatile DNA reader to unlock DNA genetic code

Also in global health news: N. Korea harvest; Zimbabwe’s health system; malaria parasite; training India's rural health workers; Myanmar recovery; health in Uganda

Fluidigm releases amplicon tagging protocol for Illumina GA II next-generation sequencer

Bombarding DNA nucleotides and mammalian meat with ‘femto-neutrons’ open new path to femtomedicine

Mapping of all fragile sites of yeast S.cerevisiae may lead to better understanding of cancer development

Biology of lung cancer varies by age and gender

Autism Speaks: Ten most significant autism research achievements in 2009

Data provide key information about epigenetic profiles for gastric cancer

Researchers explore cellular networks that regulate cell morphology

Stanford researchers use DNA minicircles to induce pluripotency in stem cells from human fat

Gene variants associated with human biological ageing identified

GIS: Tbx3 gene improves quality of stem cells reprogrammed from differentiated cells

Breakthrough research could lead to new potential treatments for malaria

Breakthrough discovery could help in developing a broad spectrum of antiviral drugs

Biochemists identify a critical piece in the evolutionary puzzle

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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