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Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

The new research findings help to understand mechanisms that lead to different types of intestinal tumors. They show that the Lef1 gene suppresses the development and growth of colorectal cancer by restricting the formation of cancer stem cell niches.

18 Nov 2021

Education and income impact survival rates after out-of-hospital cardiac arrest

Socioeconomic factors affect the risk of cardiovascular disease and the chances of recovery. New research from Karolinska Institutet in Sweden interrogates the significance of socioeconomic factors for sudden out-of-hospital cardiac arrest.

18 Nov 2021

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing "stem" cells that line and penetrate a mouse skull.

18 Nov 2021

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.

18 Nov 2021

NYU Langone Hospital—Brooklyn announces Dr. Ude Welcome as new chief of surgery

Akuezunkpa O. Ude Welcome, MD, a renowned bariatric and minimally invasive gastrointestinal surgeon, has been named chief of surgery at NYU Langone Hospital—Brooklyn.

18 Nov 2021

KHN’s ‘What the Health?’: Boosting confusion

With covid caseloads rising across much of the country, several governors and mayors are unilaterally expanding access to booster shots, getting out ahead of federal health officials.

18 Nov 2021

What is the global prevalence of long COVID?

This study aims to provide a comprehensive synthesis of information on the prevalence and symptoms of PASC.

18 Nov 2021

Study shows higher health care costs and worse outcomes for incontinent patients

Higher cost of care and worse patient outcomes are associated with incontinence and incontinence-associated dermatitis (IAD) in acute care settings, according to analysis published in the Journal of Wound, Ostomy, and Continence Nursing, the official journal of the Wound, Ostomy, and Continence Nurses Society.

18 Nov 2021

Experts develop a functional precision medicine approach to assign therapies to cancer patients

A functional precision medicine study conducted in Finland demonstrates that treatment selection based on results from drug sensitivity testing of patients' cells can be clinically useful in patients with aggressive hematological cancers.

18 Nov 2021

Scientists discover the genes used by bacteria to live within complex communities

Scientists from the Quadram Institute at the Norwich Research Park have made an important discovery into the workings of bacterial communities.

18 Nov 2021

Schools, pediatricians look to make up lost ground on non-covid vaccinations

Melissa Blatzer was determined to get her three children caught up on their routine immunizations on a recent Saturday morning at a walk-in clinic in this Denver suburb. It had been about a year since the kids' last shots, a delay Blatzer chalked up to the pandemic.

18 Nov 2021

Novel chatbot could ask emergency department visitors about social needs

Americans visit hospital emergency departments nearly 130 million times per year. Although the focus of these visits is to address acute illness and injury, doctors are increasingly finding that social needs - such as food and housing insecurity - place many patients at higher risk of getting sick and requiring emergency care.

18 Nov 2021

Boston Children's receives NIH grant to co-lead HEALthy Brain and Child Development study

Boston Children's Hospital has been awarded two five-year grants by the National Institutes of Health to co-lead the HEALthy Brain and Child Development (HBCD) study, an ambitious, comprehensive national study of brain development from birth through early childhood.

17 Nov 2021

Researchers identify compounds that tackle fungal infections in a new way

Current medications aren't particularly effective against fungi. The situation is becoming more challenging because these organisms are developing resistance to antimicrobial treatments, just as bacteria are.

17 Nov 2021

Study reveals complex interplay between diet, gut microbiota, and immune function

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

17 Nov 2021

Stroke survivors more likely than cancer survivors to continue cigarette smoking

Stroke survivors were more likely to continue cigarette smoking than cancer survivors, raising the risk that they will have more health problems or die from a subsequent stroke or heart disease, according to new research published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.

17 Nov 2021

AI and whole genome sequencing improve quick detection of infectious disease outbreaks

By coupling machine learning with whole genome sequencing, University of Pittsburgh School of Medicine and Carnegie Mellon University scientists greatly improved the quick detection of infectious disease outbreaks within a hospital setting over traditional methods for tracking outbreaks.

17 Nov 2021

Researchers identify never-before-defined subtypes of a blood cancer

Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before-defined subtypes of a blood cancer called multiple myeloma.

17 Nov 2021

Experts offers top five holiday travel safety tips for families

With a COVID-19 vaccine authorized by the Food and Drug Administration and recommended by the Centers for Disease Control and Prevention for children ages 5 and up, families may be planning long awaited holiday travel.

17 Nov 2021

Researchers identify new group of antibacterial molecules

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria.

17 Nov 2021

Hospital News and Research

Lef1 gene restricts formation of cancer stem cell niches to suppress colorectal tumor growth

Education and income impact survival rates after out-of-hospital cardiac arrest

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

NYU Langone Hospital—Brooklyn announces Dr. Ude Welcome as new chief of surgery

KHN’s ‘What the Health?’: Boosting confusion

What is the global prevalence of long COVID?

Study shows higher health care costs and worse outcomes for incontinent patients

Experts develop a functional precision medicine approach to assign therapies to cancer patients

Scientists discover the genes used by bacteria to live within complex communities

Schools, pediatricians look to make up lost ground on non-covid vaccinations

Novel chatbot could ask emergency department visitors about social needs

Boston Children's receives NIH grant to co-lead HEALthy Brain and Child Development study

Researchers identify compounds that tackle fungal infections in a new way

Study reveals complex interplay between diet, gut microbiota, and immune function

Stroke survivors more likely than cancer survivors to continue cigarette smoking

AI and whole genome sequencing improve quick detection of infectious disease outbreaks

Researchers identify never-before-defined subtypes of a blood cancer

Experts offers top five holiday travel safety tips for families

Researchers identify new group of antibacterial molecules

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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