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Mediterranean diet may benefit health in part by incorporating moderate wine consumption

Many public health warnings have been issued against alcohol consumption, even in small quantities, though the evidence for such strict limits is controversial. The current study, published in the MDPI journal Nutrients, is a narrative review focused on clearing up some of the confusion associated with alcoholic drinks.

4 Jan 2023

New insights into the bioavailability and hepatoxicity risk of neonicotinoids

Researchers quantified the residues of eight neonicotinoids in human bile samples to understand the association between internal neonicotinoid exposure and hepatotoxic outcomes.

4 Jan 2023

Study finds prevalence of caffeine intake is lower during pregnancy compared to pre-pregnancy, although it increases throughout pregnancy

In the present study, caffeine consumption was assessed before and during pregnancy, as well as fluctuations in caffeine intake and variables related to non-compliance with caffeine intake recommendations during pregnancy.

4 Jan 2023

Old antibiotic nitroxoline suggested as a treatment for MPOX

In a recent study posted to the bioRxiv* server, researchers in Germany investigated the effectiveness of the antibiotic nitroxoline against the currently circulating mpox viruses, previously called monkeypox virus (MPXV). This antibiotic has been used in Europe for about fifty years and has been proven effective in fighting biofilm infections.

3 Jan 2023

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers."

3 Jan 2023

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

A study from Washington University School of Medicine in St. Louis suggests a strategy for preventing a chronic, slow-growing type of blood cancer from progressing to an aggressive form of leukemia.

29 Dec 2022

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Researchers evaluated the efficacy of small molecule drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro.

29 Dec 2022

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Lung cancer is the leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates.

28 Dec 2022

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers.

22 Dec 2022

Recapitulating early stages of the human body plan in a dish

Although Michelangelo's masterpiece David captured the magnificence of the human body - how this exquisite body plan is exactly established during human development has puzzled scientists for more than a century.

21 Dec 2022

Newly designed antibiotic effective against multidrug-resistant bacteria

Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.

20 Dec 2022

Low ET levels in blood plasma may predict increased risk of cognitive impairment, dementia

A recent study by a team comprising researchers from the National University of Singapore and the National University Health System revealed that low levels of ergothioneine in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly.

19 Dec 2022

New imaging agent lights the way for surgeons during lung cancer surgery

Surgery, especially surgery to remove cancerous tumors, relies on a range of tools and techniques as well as on the skill of the surgeon.

19 Dec 2022

FIU researchers awarded a U.S. patent for devising methods to synthesize new arsenic-based antibiotic

Florida International University researchers have moved a step closer to producing synthetic arsenic-based drugs in their quest to solve an urgent worldwide health problem -the growing number of infections that have become antibiotic-resistant.

16 Dec 2022

New chemical compound shows promise to reverse effects of potentially deadly drugs

Drug overdoses in the United States have risen sharply in the last two decades. Nearly 92,000 people died from overdoses of illegal drugs and prescription opioids in 2020 - more than five times the number of deaths in the year 2000 - and synthetic opioids like fentanyl are one of the main culprits.

16 Dec 2022

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through drinking water.

16 Dec 2022

Eating flowers to promote health and prevent disease

Do people eat flowers? Yes, many of them. Experts say that the Greeks, Romans, and French during the Middle Ages and the English during the Victorian era included edible flowers in their cuisine, either as appetizers or to enhance the flavor of the dish.

15 Dec 2022

Compound News and Research

Mediterranean diet may benefit health in part by incorporating moderate wine consumption

New insights into the bioavailability and hepatoxicity risk of neonicotinoids

Study finds prevalence of caffeine intake is lower during pregnancy compared to pre-pregnancy, although it increases throughout pregnancy

Old antibiotic nitroxoline suggested as a treatment for MPOX

Study supports association of the ε4 alleles and polygenic profiles with Alzheimer’s disease biomarkers

Study suggests a strategy for preventing the progression of chronic leukemia to aggressive disease

Scientists explore efficacy of small molecule drugs against severe COVID-19 in vitro

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Scientists explore synthesis of griffithsin in cell-free systems

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Phase I clinical trial of PAC-1 in patients with end-stage cancers shows promising results

Recapitulating early stages of the human body plan in a dish

Newly designed antibiotic effective against multidrug-resistant bacteria

Low ET levels in blood plasma may predict increased risk of cognitive impairment, dementia

New imaging agent lights the way for surgeons during lung cancer surgery

FIU researchers awarded a U.S. patent for devising methods to synthesize new arsenic-based antibiotic

New chemical compound shows promise to reverse effects of potentially deadly drugs

Activated vitamin D3 inhibits arsenic-mediated carcinogenesis in certain skin cells, research shows

Eating flowers to promote health and prevent disease

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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