Hemoglobin News and Research

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Acetylon Pharmaceuticals presents positive preclinical data for selective HDAC1/2 inhibitors at ASH meeting

Acetylon Pharmaceuticals, Inc., the leader in the development of selective histone deacetylase (HDAC) inhibitors for enhanced therapeutic outcomes, announced that positive preclinical data for its selective HDAC1/2 inhibitors for the treatment of sickle cell disease (SCD) and β-thalassemia (bT) were presented at the 55th Annual Meeting of the American Society of Hematology (ASH) in New Orleans, LA.

11 Dec 2013

NOXXON Pharma reports interim data from two phase IIa studies of anti-CXCL12/SDF-1 Spiegelmer NOX-A12

NOXXON Pharma disclosed interim data from two independent clinical phase IIa studies of the anti-CXCL12/SDF-1 Spiegelmer olaptesed pegol (NOX-A12) at the 55th annual meeting of the American Society of Hematology in New Orleans, LA, USA from 7-10 December 2013.

9 Dec 2013

Researchers produce erythrocyte progenitor cells by transducing two genes into iPS and ES cells

By transducing two genes (c-MYC and BCL-XL) into iPS cells and ES cells, a Kyoto University research team led by Prof. Koji Eto at CiRA has succeeded in producing erythrocyte progenitor cells with almost unlimited ability to replicate in vitro, which they then differentiated successfully into mature erythrocytes. Although these erythrocytes consisted mostly of fetal-type hemoglobin, they were confirmed to have oxygen-carrying capacity and to have circulatory capacity following transfusion into mice.

6 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Wrapping in low molecular weight poly can help stabilize hemoglobin

A UConn research team has found a way to stabilize hemoglobin, the oxygen carrier protein in the blood, a discovery that could lead to the development of stable vaccines and affordable artificial blood substitutes.

4 Dec 2013

Scientific poster on EKF's Quo-Test and Quo-Lab POCT HbA1c analyzers to be presented at IDF 2013

EKF, announces the successful assessment of its Quo-Test and Quo-Lab point-of-care HbA1c analyzers within the College of Medicine, Swansea University.

From EKF Diagnostics 4 Dec 2013

Novartis to present updates on broad cancer portfolio at ASH and SABCS symposiums

Novartis will present updates on its broad cancer portfolio with more than 240 abstracts at the upcoming American Society of Hematology (ASH) annual meeting and CTRC-AACR San Antonio Breast Cancer Symposium (SABCS).

4 Dec 2013

New report on global prevalence of anemia

Despite increasing efforts to diagnose and treat anemia worldwide, there remains a surprisingly large global burden of the disease, particularly among young children and women, according to a new report on trends in anemia between 1990 and 2010.

3 Dec 2013

Researchers receive $2.5M grant to study telephone-based approach to improve diabetes treatment outcomes

More than 25 million Americans have diabetes, yet as many as 60 percent of type 2 diabetes patients do not follow treatment plans prescribed by their healthcare provider and about 50 percent fail to meet treatment recommendations for control of blood glucose levels.

26 Nov 2013

European Commission grants marketing authorization for Bayer HealthCare's Xofigo injection

Bayer HealthCare announced today that the European Commission has granted marketing authorization for Xofigo (radium Ra 223 dichloride) solution for injection for the treatment of adults with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastases. This decision follows a positive recommendation from the European Committee for Medicinal Products for Human Use in September of this year.

15 Nov 2013

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

FibroGen, Inc. (FibroGen), today announced that data from a China-based Phase 2 study of roxadustat (FG-4592), a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease (CKD) and end-stage renal disease (ESRD), were presented in an oral session at the 2013 American Society of Nephrology (ASN) Kidney Week in Atlanta, Georgia.

13 Nov 2013

Triferic drug is effective in preventing iron deficiency in patients with chronic kidney disease

Doctors at the North Shore-LIJ Health System on Saturday will present late-breaking data showing that an investigational drug Triferic is well tolerated and effective in treating iron deficiency in patients with chronic kidney disease undergoing dialysis.

11 Nov 2013

Drug used to treat intestinal worms could protect people from periodontitis, says study

A drug currently used to treat intestinal worms could protect people from periodontitis, an advanced gum disease, which untreated can erode the structures-including bone-that hold the teeth in the jaw. The research was published ahead of print in Antimicrobial Agents and Chemotherapy.

11 Nov 2013

Researchers explore strategies that would optimize fresher blood for patients

Although clinical evidence is lacking on the relationship between the storage time of red blood cells and outcomes in transfused patients, the authors of a review article in the November 2013 issue of The Annals of Thoracic Surgery are advocating for a modernized blood management system—similar to inventory management systems seen in the retail sector—to potentially reduce patient complications.

31 Oct 2013

Honey may be detrimental for patients with type 2 diabetes

Honey may be detrimental for patients with type 2 diabetes because of the great quantities of sugars it contains.

31 Oct 2013

Incyte announces results of Phase II clinical trial of oral JAK1 inhibitor in patients with RA

Incyte Corporation (Nasdaq: INCY) announced results from a 12-week, placebo-controlled, dose-escalationin involving 60 patients with active rheumatoid arthritis for its proprietary oral JAK1 inhibitor.

29 Oct 2013

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Research from Boston University School of Medicine suggests that testosterone treatment in hypogonadal (testosterone deficient) men restores normal lipid profiles and may reduce the risk of cardiovascular disease. These finding currently appear online in the International Journal of Clinical Practice.

24 Oct 2013

EKF publishes new white paper detailing successful evaluation of POCT HbA1c analyzers

EKF, announces publication of a new white paper detailing the successful external evaluation of its Quo-Test and Quo-Lab glycated hemoglobin analyzers.

From EKF Diagnostics 23 Oct 2013

Research: Low levels of vitamin D appear to increase child's risk of anemia

Low levels of the "sunshine" vitamin D appear to increase a child's risk of anemia, according to new research led by investigators at the Johns Hopkins Children's Center. The study, published online Oct. 10 in the Journal of Pediatrics, is believed to be the first one to extensively explore the link between the two conditions in children.

22 Oct 2013

New prognostic tool forecasts survival of patients with advanced prostate cancer

For men with advanced prostate cancer that has progressed after taking hormones and undergoing chemotherapy, getting an accurate prognosis is critical to determine the next steps for treatment.

19 Oct 2013

Hemoglobin News and Research

Acetylon Pharmaceuticals presents positive preclinical data for selective HDAC1/2 inhibitors at ASH meeting

NOXXON Pharma reports interim data from two phase IIa studies of anti-CXCL12/SDF-1 Spiegelmer NOX-A12

Researchers produce erythrocyte progenitor cells by transducing two genes into iPS and ES cells

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Wrapping in low molecular weight poly can help stabilize hemoglobin

Scientific poster on EKF's Quo-Test and Quo-Lab POCT HbA1c analyzers to be presented at IDF 2013

Novartis to present updates on broad cancer portfolio at ASH and SABCS symposiums

New report on global prevalence of anemia

Researchers receive $2.5M grant to study telephone-based approach to improve diabetes treatment outcomes

European Commission grants marketing authorization for Bayer HealthCare's Xofigo injection

FibroGen presents China-based Phase 2 study data of roxadustat for treatment of CKD patients

Triferic drug is effective in preventing iron deficiency in patients with chronic kidney disease

Drug used to treat intestinal worms could protect people from periodontitis, says study

Researchers explore strategies that would optimize fresher blood for patients

Honey may be detrimental for patients with type 2 diabetes

Incyte announces results of Phase II clinical trial of oral JAK1 inhibitor in patients with RA

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

EKF publishes new white paper detailing successful evaluation of POCT HbA1c analyzers

Research: Low levels of vitamin D appear to increase child's risk of anemia

New prognostic tool forecasts survival of patients with advanced prostate cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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