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Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

Virally mediated gene therapy could potentially treat genetic hearing loss

By 2050, one in 10 individuals are expected to live with some form of hearing loss. Of the hundreds of millions of cases of hearing loss affecting individuals worldwide, genetic hearing loss is often the most difficult to treat.

26 May 2023

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Several phase 3 studies conducted by researchers from Dana-Farber Cancer Institute show promising results for patients with rectal, brain, and kidney cancers. The results of these studies, along with dozens of others led by Dana-Farber researchers, will be presented at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago.

26 May 2023

Fission yeast study sheds new light on gross chromosomal rearrangement

When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body's genetic code, DNA, which is stored in structures known as chromosomes, can bring about mutations in the body.

26 May 2023

Adoption of Mediterranean diet shows promise in easing symptoms for myeloproliferative neoplasm patients

Researchers assess the feasibility of an education-focused Mediterranean diet intervention among myeloproliferative neoplasm patients.

25 May 2023

Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus

New animal research is helping explain why at least five people have become HIV-free after receiving a stem cell transplant.

25 May 2023

Combination of genetic and environmental factors increases the risk of cleft lip

A cleft lip or palate arises from the combined effects of genes and inflammatory risk factors experienced during pregnancy, such as smoking or infections, finds a new study led by UCL researchers.

24 May 2023

bit.bio launches new custom disease model cells offering, advancing disease research & drug discovery

Researchers can now order their mutation of choice in bit.bio’s opti-oxTM powered human-iPSC derived cells, receiving consistent, defined, cryopreserved products that can be immediately incorporated into drug discovery workflows.

From bit.bio 24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

To commemorate World Schizophrenia Awareness Day, we spoke to three researchers from the Queensland Brain Institiute about their research, and why it is so important to raise awareness around Schizophrenia

23 May 2023

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

A new study shows that total RPE65 protein levels in mice with autosomal dominant retinitis pigmentosa were doubled following subretinal delivery of adeno-associated virus (AAV)-RPE65 gene supplementation.

23 May 2023

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center will discuss the latest research and clinical trial results on combination therapies for breast cancer, a potential new treatment for patients with recurrent glioma, and advances in PSMA PET guided radiotherapy for patients with prostate cancer, among other topics, at the American Society of Clinical Oncology's annual meeting.

23 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

New technique may reveal signs of Parkinson's disease in urine samples

A team led by researchers at Purdue University and Purdue spinoff company Tymora Analytical Operations has developed a technique that may reveal signs of Parkinson's disease in urine samples.

17 May 2023

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

As part of the Foundation for the National Institutes of Health Accelerating Medicines Partnership Bespoke Gene Therapy Consortium, Nemours Children's Health has been chosen to conduct a first-of-its-kind gene therapy clinical trial for Morquio A syndrome.

16 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Mutation News and Research

Novel assay for identifying individuals with synucleinopathies using serum samples

Virally mediated gene therapy could potentially treat genetic hearing loss

Phase 3 studies for rectal, brain, and kidney cancers to be presented by Dana-Farber researchers at ASCO 2023

Fission yeast study sheds new light on gross chromosomal rearrangement

Adoption of Mediterranean diet shows promise in easing symptoms for myeloproliferative neoplasm patients

Nonhuman primate study helps explain how stem cell transplantation can kill HIV virus

Combination of genetic and environmental factors increases the risk of cleft lip

bit.bio launches new custom disease model cells offering, advancing disease research & drug discovery

The adaptive immunity of human endemic viruses

Revolutionizing Schizophrenia Research with the Queensland Brain Institute

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

New technique may reveal signs of Parkinson's disease in urine samples

Nemours Children's Health selected to conduct first gene therapy clinical trial for Morquio A syndrome

Newly identified genetic variant provides protection from Alzheimer's disease

Humanized mouse model for rare genetic disease developed for the first time

SARS-CoV-2 variants show altered glycan processing

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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