Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

First cases of co-infection with Delta and Omicron identified during local co-circulation of both SARS-CoV-2 lineages

Researchers revealed the co-infection of the SARS-CoV-2 Delta and Omicron variants in two epidemiologically unrelated patients suffering from chronic kidney disease and requiring hemodialysis

17 Feb 2022

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Researchers discuss the genomic and virological characterization of SARS-CoV-2 variants among unvaccinated and vaccinated U.S military personnel.

16 Feb 2022

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Researchers present a simple and efficient plasmonic-magnetic nanorobot for the detection of SARS-CoV-2 RNA.

16 Feb 2022

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Researchers compare the incidence rate of reinfection in convalescent and unvaccinated people to that in recovered and single-dose vaccinated people.

16 Feb 2022

Study confirms that pets can harbor SARS-CoV-2 infection

A new study looks at how dogs and cats within households are susceptible to COVID-19 infection from humans, and whether they act as reservoir species.

16 Feb 2022

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

A new study evaluated the pregnancy outcomes of pregnant women in the third trimester who were infected by SARS-CoV-2 for the detection of the virus in the placenta and different samples of the newborn as well as detection of antibodies in the cord blood.

16 Feb 2022

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

The multiplex detection approach outlined in this study has the potential to address the need to rapidly characterize the phenotype and clinical response to continually emerging SARS-CoV-2 variants as the COVID-19 pandemic continues.

16 Feb 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

Canadian study estimates incidence rate of reinfection in healthcare workers

Researchers from various Canadian institutions document all cases of reinfection discovered during the first year of the project.

15 Feb 2022

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

In a new study, a team of researchers demonstrated multiple site-directed mutagenesis as an efficient, easy, and more economically viable alternative to commercial gene synthesis to highlight how specific residues can contribute to the molecular structure and functioning of proteins.

15 Feb 2022

South African population reveal durable protection by prior infection against pre-Omicron variants

A recent study explored the buildup of immunity developed post-SARS-CoV-2 infection in African people and the impact of SARS-CoV-2 Omicron VOC on the COVID-19 pandemic.

15 Feb 2022

Study explores SARS-CoV-2 antibodies in children

Researchers set out to explore how COVID-19 antibody responses persist over time after natural infection in children.

15 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

In a recent study posted to the bioRxiv* preprint server, a team of researchers from Washington, United States, investigated the transmission of viral genetic diversity during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) superspreading outbreak among the crew members on a fishing boat.

14 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

First survey on Omicron BA.2 in France

In a recent study posted to the medRxiv* preprint server, researchers described the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 21L/BA.2 Omicron variant in south-eastern France.

14 Feb 2022

Antihistamines may offer hope for long COVID patients

Researchers offer hope that an inexpensive over-the-counter medication could improve long COVID symptoms for a large proportion of these patients.

14 Feb 2022

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Researchers reported the development and validation of a two-reaction multiplex reverse transcription-quantitative polymerase chain reaction genotyping strategy that distinguishes SARS-CoV-2 variants of concern.

14 Feb 2022

Study explores the gut microbiome of COVID-19 patients

Researchers investigated the changes in the gut microbiome and the presence of SARS-CoV-2 in stool samples of COVID-19 patients.

14 Feb 2022

Testes found to be a viral reservoir for SARS-CoV-2 replication

In a recent study posted to the medRxiv* pre-print server, researchers used a suite of methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the testis of patients who died from coronavirus disease 2019 (COVID-19) to gain insights into SARS-CoV-2 tropism inside testis and its impact on male fertility.

13 Feb 2022

Polymerase Chain Reaction News and Research

Further Reading

First cases of co-infection with Delta and Omicron identified during local co-circulation of both SARS-CoV-2 lineages

Characterization of SARS-CoV-2 variants in unvaccinated and vaccinated U.S. military

Detection of SARS-CoV-2 RNA by plasmonic-magnetic nanorobots

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Study confirms that pets can harbor SARS-CoV-2 infection

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

CRISPR-Cas12a assay to diagnose SARS-CoV-2 infection and detect strain-specific SNPs for variant identification

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

Canadian study estimates incidence rate of reinfection in healthcare workers

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

South African population reveal durable protection by prior infection against pre-Omicron variants

Study explores SARS-CoV-2 antibodies in children

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Study investigates the spread of SARS-CoV-2 genetic diversity on a fishing boat

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

First survey on Omicron BA.2 in France

Antihistamines may offer hope for long COVID patients

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Study explores the gut microbiome of COVID-19 patients

Testes found to be a viral reservoir for SARS-CoV-2 replication

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