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Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

Wyss Institute's DNA nanotechnology-driven SPEAR protein-detection technology licensed to Spear Bio

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Spear Bio, Inc.announced that the Institute's DNA nanotechnology-driven ultrasensitive SPEAR protein-detection technology has been licensed to the newly formed Boston-based startup.

23 Aug 2022

Insights into the biology of the monkeypox virus

Researchers provided insights into monkeypox virus structural characteristics, epidemiology, transmission, zoonotic reservoirs, pathogenesis, and clinical management.

23 Aug 2022

New treatment may help counteract food allergies and inflammatory diseases in future

Although many people with dietary allergies experience mild symptoms when exposed to triggering foods, some face potentially fatal consequences.

22 Aug 2022

Tiny, touch-based sensor rapidly detects lithium levels from sweat on the surface of a fingertip

Lithium can alleviate the symptoms of bipolar disorder and depression - if taken in just the right amount.

22 Aug 2022

The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

Researchers conducted a phase III clinical trial to test the effectiveness of three repurposed drugs - metformin, ivermectin, and fluvoxamine, in preventing progression to severe COVID-19.

22 Aug 2022

How do BNT162b2 vaccine-induced neutralizing and non-neutralizing antibodies synergize to promote protection against SARS-CoV-2?

Scientists explored the COVID-19 BNT162b2 vaccine triggered non-neutralizing and neutralizing antibody functions.

18 Aug 2022

Eating grapes may reduce the risk of fatty liver disease

In a recent study published in the journal Foods, eating grapes can extend life expectancy by five years and reduce non-alcoholic fatty liver disease risk in mice fed high-fat diets.

17 Aug 2022

Using cameras and filmmaking skills to improve dietary diversity among Indigenous people in India

A unique initiative is helping Indigenous people in India exchange knowledge about locally available foods to improve dietary diversity - part of the UN Sustainable Development Goal related to food security and nutrition.

16 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

Study uncovers a key role for MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy

A study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and led by Dr. Guadalupe Sabio has identified a key role for the MKK3/6–p38γ/δ signaling pathway in the development of cardiac hypertrophy.

16 Aug 2022

Study offers more quantitative insights into long-term health risks of thirdhand smoke exposure

Some smells seem to seep into everything they touch. Tobacco smoke is one of the worst offenders.

15 Aug 2022

Cancer-related fatigue contributes to balance problems following exposure to chemotherapy for breast cancer

For many women who have undergone chemotherapy for breast cancer, cancer-related fatigue (CRF) is a persistent side effect – and one that contributes to ongoing balance problems, suggests a paper in Rehabilitation Oncology, official journal of APTA Oncology, an academy of the American Physical Therapy Association (APTA).

15 Aug 2022

Recombination most often occurs on the COVID-19 phylogenetic tree in the form of 'long branches'

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to attach to and infect host cells.

11 Aug 2022

OICR funding to help five research projects take the next step toward advancing cancer care

Five Ontario-based research projects will take the next step toward advancing cancer care in the province thanks to funding from the Ontario Institute for Cancer Research (OICR).

11 Aug 2022

Crying out for new disease diagnoses

In this interview, we speak to Dr. Fei Liu and Dr. Luke P. Lee about their new iTears platform and how it could help to diagnose disease from tears.

11 Aug 2022

Novel model reveals how genomic instability arises in histologically benign tissue

Understanding which cells give rise to which areas of cancer can improve our understanding of how a tumor has grown and developed, including how it has changed genetically, over time. This has been made possible using a new technique called spatial transcriptomics, which allows scientists to see what genetic changes take place without breaking up the tissue they're looking at.

11 Aug 2022

Repurposed drug shows promise as potential new treatment for motor neuron disease

A drug typically used to treat enlarged prostates and high blood pressure has shown promise as a potential new therapy for motor neuron disease (MND), according to a new study.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Scientists review current literature associated with the role of the gut-brain axis in AD pathogenesis.

9 Aug 2022

Translation News and Research

Optimized human small intestinal organoids can help better study the functioning of small intestines

Wyss Institute's DNA nanotechnology-driven SPEAR protein-detection technology licensed to Spear Bio

Insights into the biology of the monkeypox virus

New treatment may help counteract food allergies and inflammatory diseases in future

Tiny, touch-based sensor rapidly detects lithium levels from sweat on the surface of a fingertip

The effectiveness of three repurposed drugs in preventing serious SARS-CoV-2 infection in non-hospitalized adults

How do BNT162b2 vaccine-induced neutralizing and non-neutralizing antibodies synergize to promote protection against SARS-CoV-2?

Eating grapes may reduce the risk of fatty liver disease

Using cameras and filmmaking skills to improve dietary diversity among Indigenous people in India

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

Study uncovers a key role for MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy

Study offers more quantitative insights into long-term health risks of thirdhand smoke exposure

Cancer-related fatigue contributes to balance problems following exposure to chemotherapy for breast cancer

Recombination most often occurs on the COVID-19 phylogenetic tree in the form of 'long branches'

OICR funding to help five research projects take the next step toward advancing cancer care

Crying out for new disease diagnoses

Novel model reveals how genomic instability arises in histologically benign tissue

Repurposed drug shows promise as potential new treatment for motor neuron disease

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Alzheimer’s disease is associated with characteristic gut metabolomic signatures

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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