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New target for the development of anti-influenza drugs

Scientists at Cure Lab, Inc., a biotechnology company based in Canton, Massachusetts, in collaboration with researchers at Boston University and Harvard Medical School have discovered a potential new target for the development of anti-influenza (flu) drugs, including those that may be effective against potentially pandemic influenza strains like H5N1.

17 Aug 2007

Scientists describe a new way of creating novel enzymes

The intricate interplay of proteins and other chemicals that underlies most biological activities requires the participation of enzymes, specialized molecules that accelerate chemical reactions between molecules.

17 Aug 2007

First biomarker discovered that predicts prostate cancer outcome

Mayo Clinic researchers have identified the first immune molecule that appears to play a role in prostate cancer development and in predicting cancer recurrence and progression after surgery.

17 Aug 2007

Preventing the spread of zoonotic diseases

Instead of attacking wild birds for our new disease problems, a far more cost effective approach should focus on keeping wild animals separate in the places where they often commingle: in wildlife markets and international trade, according to wildlife health experts from the Wildlife Conservation Society (WCS) and the United Nations Food and Agriculture Organization (FAO) in a recent issue of the prestigious Journal of Wildlife Diseases.

17 Aug 2007

Effectiveness of mouse breeds that mimic Alzheimer's disease symptoms questioned

Scientists have shown that recently developed mouse breeds that mimic the symptoms of Alzheimer's disease (AD) may not be as effective as previously assumed.

17 Aug 2007

New insight into fragile X tremor/ataxia syndrome

Researchers have reported new insight into the pathology underlying a recently identified neurological disorder that strikes middle-aged adults that is caused by alterations in the same gene that causes fragile X syndrome.

17 Aug 2007

Combination of drugs might decrease the chance of chronic myeloid leukemia returning

Individuals with chronic myeloid leukemia (CML) are treated first with a drug known as imatinib (Gleevec), which targets the protein known to cause the cancer (BCR-ABL).

17 Aug 2007

Metformin kills some cancer cells

Researchers at the University of Pennsylvania School of Medicine have found that a commonly prescribed diabetes drug kills tumor cells that lack a key regulatory gene called p53.

16 Aug 2007

Breast cancer prevention practices vary across Canada

Breast cancer preventive practices for Canadian women carrying the cancer gene vary across the country, says University of Toronto research, and many women are not taking advantage of the options available.

16 Aug 2007

Why is heart disease so prevalent among diabetics?

Heart disease hits people with diabetes twice as often as people without diabetes.

13 Aug 2007

Mitochondrial DNA variants are linked to risk factors for type 2 diabetes

Researchers report for the first time that genetic variants in mitochondria,energy-producing structures harboring DNA that are inherited only from the mother,are directly linked to metabolic markers for type 2 diabetes.

13 Aug 2007

Bird flu death in Bali - Australians on alert

Health officials in Indonesia have confirmed the first human death from bird flu in Bali in a village in the north-west district of Jembrana, an area where poultry is known to be affected.

13 Aug 2007

New drug targets for multiple myeloma

Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.

13 Aug 2007

New cancer stem cells could aid breast cancer research

In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as "queens," possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the "worker" cells that form the bulk of the tumor.

13 Aug 2007

Antioxidant overload

Despite the popular notion that antioxidants, such as vitamins C and E, offer health-promoting benefits by protecting against damaging free radicals, a new study in the August 10 issue of the journal Cell reveals that, in fact, balance is the key.

12 Aug 2007

Light-activated molecules used to induce apoptosis in cancer cells

A key challenge facing doctors as they treat patients suffering from cancer or other diseases resulting from genetic mutations is that the drugs at their disposal often don't discriminate between healthy cells and dangerous ones -- think of the brute-force approach of chemotherapy, for instance.

12 Aug 2007

Scientists prepare for future pandemic strains of H5N1

Preparing vaccines and therapeutics that target a future mutant strain of H5N1 influenza virus sounds like science fiction, but it may be possible, according to a team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), and a collaborator at Emory University School of Medicine.

11 Aug 2007

Second bird flu death in Vietnam in a week

Vietnamese authorities have confirmed another new bird-flu death, this time the victim is a 15-year-old boy.

8 Aug 2007

Indonesia reluctant when it comes to sharing bird flu samples

Indonesia, the country with the highest number of human deaths from the bird flu, remains reluctant to share samples of live bird flu virus for research.

7 Aug 2007

New research may lead to future gene therapies for patients with sickle cell anemia and beta-thalassemia

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

7 Aug 2007