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Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

Aerosol transmission through new vs. reused N95 masks

The world is grappling with the worst pandemic in over 100 years. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus which emerged in China in December 2019 but has now spread across the globe. With a rapid rate of transmission, SARS-CoV-2 has now affected over 4.88 million people and resulted in over 322,000 deaths.

19 May 2020

The use of rheumatoid arthritis drug sarilumab in severe COVID-19 pneumonia

A new study published on the preprint server medRxiv* in May 2020 reports the beneficial effects of the monoclonal antibody sarilumab in severe COVID-19 pneumonia.

19 May 2020

Do parasites protect against SARS-CoV-2?

The world has rarely seen such a readily transmissible infection as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) over the last century. Within five months, the virus has created a Tsunami of COVID-19 positive cases, comprising almost 4.88 million people and causing 322,000 deaths.

19 May 2020

Does COVID-19 infect peripheral blood cells?

The emergence of the novel coronavirus outbreak in December 2019 was followed by its spread on a global scale unparalleled in the last 100 years. At present, it has claimed over 322,000 lives the world over, with over 4.88 million cases having tested positive.

19 May 2020

Researchers propose a safer approach to splitting ventilators

As more Covid-19 patients experience acute respiratory distress, there has been much debate over the idea of sharing ventilators, which involves splitting air tubes into multiple branches so that two or more patients can be connected to the same machine.

19 May 2020

Did SARS-CoV-2 adapt to humans long before the index case?

A new study from Canada and the U.S. suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have already been pre-adapted to human transmission when it emerged in late 2019, which means there may be lingering populations of progenitor SARS-CoV-2 adept for human transmission and coronavirus disease (COVID-19) re-emergence. The research is published on the preprint server bioRxiv in May 2020.

19 May 2020

Sleep apnea may increase the risk of severe COVID-19, say researchers

An analysis conducted by researchers at the University of Turku and Turku University Hospital in Finland has suggested that obstructive sleep apnea (OSA) may be a risk factor for severe coronavirus disease 2019 (COVID-2019).

19 May 2020

No SARS-COV-2 among young children in Belgium attending daycare, report researchers

A study conducted by researchers in Belgium has found no evidence to support concerns that asymptomatic young children may be a source of severe acute respiratory syndrome coronavirus disease 2 (SARS-CoV-2) transmission.

19 May 2020

Modified clinical trial design to meet urgent community needs during COVID-19 pandemic

A new paper published online in the Annals of the American Thoracic Society describes a nimble, pragmatic and rigorous multicenter clinical trial design to meet urgent community needs in the face of the COVID-19 pandemic.

19 May 2020

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

19 May 2020

NEJM Group releases a series of five Covid-19 interactive cases

NEJM Group today released Covid-19 Rx: Treatment Simulations, a series of five Covid-19 interactive cases that range from a mild self-limited flu-like illness to life-threatening multi-organ failure.

19 May 2020

Researchers are developing a diagnostic test that predicts the advanced stages of COVID-19 patients

A research team from the University of Valencia, led by Professor Juan Saus from the Department of Biochemistry and Molecular Biology, is developing a project to provide the healthcare system with a diagnostic test that anticipates the entry into advanced stages of patients with COVID-19 and a scalable oral treatment for the disease.

19 May 2020

Common cytokine profile in ARDS, severe COVID-19 and sepsis

Many lives have been lost to the severe pneumonic disease COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), during the ongoing pandemic. The reason for the critical lung injury that results in a fatal outcome in a significant minority of patients has been supposed to be the dramatic oversecretion of pro-inflammatory cytokines and chemokines triggered by the virus.

19 May 2020

New animal model for COVID-19

As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage the world, scientists are frantically searching for a vaccine or new drug that will effectively counter the lethal effects of the virus that leads to COVID-19 disease.

19 May 2020

New UV disinfection technology is effective for deactivating SARS-CoV-2 on surfaces

Surfaces contaminated with SARS-CoV-2, the virus that causes COVID-19, pose a grave threat to the safety of healthcare workers, patients, frontline responders, military service members, cruise line passengers, hotel guests and people everywhere.

19 May 2020

Three FDA-approved drugs can block the replication of COVID-19 virus

Three drugs that are already approved by the Food and Drug Administration (FDA) or other international agencies can block the production of the novel coronavirus that causes COVID-19 in human cells, according to computational and pharmaceutical studies performed by UT Southwestern scientists.

19 May 2020