Immune System News and Research

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Researchers successfully generate cells of immune system to target, destroy cancer cells

Researchers at the Max Delbrück Center for Molecular Medicine Berlin-Buch and Charité - Universitätsmedizin Berlin, Campus Berlin-Buch, have succeeded in generating cells of the immune system to specifically target and destroy cancer cells.

20 Mar 2015

Vitamin D plays major role in preventing diabetes and atherosclerosis

In recent years, a deficiency of vitamin D has been linked to type 2 diabetes and heart disease, two illnesses that commonly occur together and are the most common cause of illness and death in Western countries. Both disorders are rooted in chronic inflammation, which leads to insulin resistance and the buildup of artery-clogging plaque.

19 Mar 2015

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Pharmacyclics, Inc. today announced that new pre-clinical and clinical data for ibrutinib (IMBRUVICA) will be highlighted at the 2015 American Association for Cancer Research Annual Meeting to be held April 18 – 22, 2015, in Philadelphia, PA.

19 Mar 2015

IU researchers reveal how Toxoplasma parasites modify brain cells

Rodents infected with a common parasite lose their fear of cats, resulting in easy meals for the felines. Now IU School of Medicine researchers have identified a new way the parasite may modify brain cells, possibly helping explain changes in the behavior of mice -- and humans.

19 Mar 2015

Austrian Centre of Industrial Biotechnology develops method to reduce production costs of valuable drugs

Imagine a loved relative suffering from cancer - and you could not afford a treatment because the drugs are too expensive. The Austrian Centre of Industrial Biotechnology (acib) developed a method with the power to reduce production costs of highly valued drugs significantly.

19 Mar 2015

OSU researchers find link between low levels of vitamin D and depression in young women

A new study from Oregon State University suggests there is a relationship between low levels of vitamin D and depression in otherwise healthy young women.

19 Mar 2015

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task.

18 Mar 2015

Researchers identify promising new approach to treat pulmonary fibrosis

By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children's Hospital Los Angeles, along with colleagues in Mexico and Canada, have identified a promising new approach for the treatment of pulmonary fibrosis.

18 Mar 2015

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Scientists from the Florida campus of The Scripps Research Institute have successfully tested a potent synthetic compound that prevents type 1 diabetes in animal models of the disease.

18 Mar 2015

Scientists examine how substances at low concentrations may impact human health

A public and scientific discussion is currently taking place focusing on the question whether substances at low concentrations may lead to health impairments in humans. For this reason, an increasing number of experimental studies to test such effects are currently conducted using different chemicals.

18 Mar 2015

Study reveals novel approach to treat breast cancer

A means of reprogramming a flawed immune response into an efficient anti-tumoral one was brought to light by the results of a translational trial relating to breast cancer. Thanks to the innovative combination of mathematical modelisation and experimentation, only 20 tests were necessary, whereas traditional experimentation would have required 596 tests to obtain the same results.

18 Mar 2015

First clinical trial of new malaria vaccine held in Equatorial Guinea

Equatorial Guinea has held the first clinical trial of a new malaria vaccine known as PfSPZ. Three volunteers participated this month in the trial of the vaccine, which was developed by the American biotechnology company Sanaria. The trial took place at the La Paz Medical Center, the country's premier medical facility, located in Sipopo, just outside the capital.

18 Mar 2015

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

The Ben May Department for Cancer Research at the University of Chicago will hold a day-long symposium on cancer immunotherapy for physicians and researchers.

18 Mar 2015

New drug-like molecule shows promise in preventing MS progression

Walter and Eliza Hall Institute scientists have developed a new drug-like molecule that can halt inflammation and has shown promise in preventing the progression of multiple sclerosis (MS).

17 Mar 2015

CUMC researchers identify mechanism of kidney transplant tolerance

Columbia University Medical Center researchers have pinpointed the immune system mechanism that allows a kidney transplant to be accepted without lifelong immunosuppressive drugs, a significant step toward reducing or eliminating the need for costly and potentially toxic immunosuppressant drugs and improving long-term transplant success.

17 Mar 2015

Therapists twice as likely to misdiagnose mental illness in patients from socially disadvantaged groups

The shooting of an unarmed teenager in Ferguson, MO, has ignited a global discussion about implicit racial bias. One group of people you might think would be immune from this hidden bias is clinical therapists, people trained to understand the human mind. But a new field study finds that the social identities of patients and their therapists affect the accuracy of the diagnosis: Therapists were twice as likely to misdiagnose mental illness when their patients were members of a disadvantaged, compared to an advantaged, group.

17 Mar 2015

Ludwig researchers establish proof of concept for new approach to drug design

Exploring the fundamental mechanism by which a cell-surface receptor transmits its signal, an international team of Ludwig researchers and their colleagues has established proof of concept for an entirely new approach to drug design. They report that a class of synthetic molecules known as diabodies can, from outside the cell, latch onto a target receptor and manipulate it in such a manner as to induce distinct and varying effects within cells and tissues.

17 Mar 2015

Comprehensive review of sex hormones' role in female reproductive tract

Charles R. Wira, PhD, and colleagues at Dartmouth's Geisel School of Medicine have presented a comprehensive review of the role of sex hormones in the geography of the female reproductive tract and evidence supporting a "window of vulnerability" to HIV and other sexually transmitted infections (STIs).

17 Mar 2015

Inadequate vaccine coverage drives Disneyland measles outbreak

Inadequate vaccine coverage is likely a driving force behind the ongoing Disneyland measles outbreak, according to calculations by a research team at Boston Children's Hospital.

16 Mar 2015

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

NantWorks, Inc. and Sorrento Therapeutics, Inc., announced today that they have entered into a binding agreement to initiate a global collaboration to discover and develop novel anti-cancer immunotherapies derived from Sorrento's proprietary G-MAB library against neoepitopes of tumor-specific antigens discovered using NantWorks' proprietary pan-omics based, precision medicine approach.

16 Mar 2015

Immune System News and Research

Researchers successfully generate cells of immune system to target, destroy cancer cells

Vitamin D plays major role in preventing diabetes and atherosclerosis

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

IU researchers reveal how Toxoplasma parasites modify brain cells

Austrian Centre of Industrial Biotechnology develops method to reduce production costs of valuable drugs

OSU researchers find link between low levels of vitamin D and depression in young women

Researchers discover new metabolic mechanisms linked to macrophage polarization

Researchers identify promising new approach to treat pulmonary fibrosis

TSRI scientists successfully test potential preventative therapy for type 1 diabetes in animal models

Scientists examine how substances at low concentrations may impact human health

Study reveals novel approach to treat breast cancer

First clinical trial of new malaria vaccine held in Equatorial Guinea

Physicians, researchers to discuss advances in cancer immunotherapies at UChicago symposium

New drug-like molecule shows promise in preventing MS progression

CUMC researchers identify mechanism of kidney transplant tolerance

Therapists twice as likely to misdiagnose mental illness in patients from socially disadvantaged groups

Ludwig researchers establish proof of concept for new approach to drug design

Comprehensive review of sex hormones' role in female reproductive tract

Inadequate vaccine coverage drives Disneyland measles outbreak

NantWorks, Sorrento collaborate to discover and develop novel anti-cancer immunotherapies

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