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Respiratory antivirals and risk to breastfeeding women

Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.

4 Mar 2020

Personalized approach in IVF increases success rate

Becoming pregnant can be a lengthy and stressful process for one in every six couples. As fertility treatment protocols are based on the "average woman", approximately 30 per cent of patients need a personalised approach in IVF.

4 Mar 2020

How do cells protect themselves from viruses?

Amid the coronavirus outbreak that is wreaking havoc across the globe, it is essential to know how the cells of the body evade infection from viruses. A team of scientists has explained the mechanism that takes place in case a virus penetrates the body.

4 Mar 2020

Two genome sequences of coronavirus (COVID-19) show possible internal transmission

The coronavirus disease (COVID-19) is rapidly spreading around the globe. With the high infection rate and spread of the virus to more than 80 countries, scientists are racing to study the nature of the virus, in the hopes of finding new vaccines and therapeutics.

4 Mar 2020

Family history elevates heart disease mortality risk in women who had premature removal of ovaries

Women who proactively have their ovaries removed to minimize their cancer risk may face a greater risk--premature death because of heart disease.

4 Mar 2020

Preclinical data of Ocugen's OCU400 genetic modifier published in Nature Gene Therapy

Ocugen, Inc., a clinical-stage company focused on discovering, developing and commercializing transformative therapies to treat rare and underserved ophthalmic diseases, announced today the publication in Nature Gene Therapy of preclinical data of nuclear hormone receptor gene NR2E3 as a genetic modifier and therapeutic agent to treat multiple retinal degenerative diseases.

3 Mar 2020

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Desperate times need desperate measures. Accordingly, scientists, today published a new study in the journal Cell Host and Microbe in March 2020, showing that drugs that prevent the acquisition of DNA-borne antibiotic resistance traits from their surroundings by bacteria can stop mice from becoming resistant to the action of the antibiotics.

3 Mar 2020

Subpopulations of leukemic cells present at diagnosis can cause relapse in children with ALL

Scientists at St. Jude Children's Research Hospital and Princess Margaret Cancer Centre in Toronto, Canada, have reported that subpopulations of leukemic cells present at diagnosis can cause relapse in children with acute lymphoblastic leukemia.

3 Mar 2020

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers.

3 Mar 2020

Researchers detect a novel cause of acquired lipodystrophy

Nonalcoholic fatty liver disease (NAFLD) is mostly diagnosed in overweight and obese people. However, severe forms of NAFLD can also be detected in rare genetic diseases such as lipodystrophy or in patients with HIV, putting them at a high risk for developing liver failure, diabetes and cardiovascular diseases.

3 Mar 2020

Increasing energy supply within injured spinal cord nerves could help them heal

When the spinal cord is injured, the damaged nerve fibers--called axons--are normally incapable of regrowth, leading to permanent loss of function.

3 Mar 2020

Study identifies a protein and signaling pathway that may contribute to sudden cardiac death

By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.

3 Mar 2020

Rapamycin worsens diseases and premature aging in mice with short telomeres

In the past few decades, it was discovered that the rate at which we age is strongly influenced by biochemical processes that, at least in animal models, can be controlled in the laboratory.

3 Mar 2020

CTSI to host Translational Research Day 2020: Broadly-Engaged Team Science

Tufts Clinical and Translational Science Institute (CTSI) will host Translational Research Day 2020: Broadly-Engaged Team Science on Friday, March 6.

2 Mar 2020

Researchers identify major landmarks of peripheral artery disease recovery

Novel biomedical advances that show promise in the lab often fall short in clinical trials. For researchers studying peripheral artery disease, this is made more difficult by a lack of standardized metrics for what recovery looks like.

2 Mar 2020

Mayo study recommends genetic testing to all women diagnosed with breast cancer under the age of 66

A study by researchers at Mayo Clinic published this week in the Journal of Clinical Oncology suggests that all women with a breast cancer diagnosis under the age of 66 be offered germline genetic testing to determine if they have a gene mutation known to increase the risk of developing other cancers and cancers among blood relatives.

2 Mar 2020