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Alzheimer’s drug trial: an interview with Geoffrey Kempler, Chairman & CEO Prana Biotechnology

Approval for the IMAGINE trial was granted by the Austin Health Research Ethics Committee in November 2011, with the first patients dosed in March the following year. However, well before the trial was approved, PBT2 had already shown promise in significantly changing Abeta levels in spinal fluid while improving cognition in a previous 12-week trial conducted in 2006.

28 Aug 2013

JHI signs agreement with HMV to enhance clinical care, patient safety and nursing education

Enhancements in clinical care and patient safety, medical research and nursing initiatives are at the core of a new affiliation agreement signed on Aug. 27 by Johns Hopkins Medicine International, Baltimore, USA, and Hospital Moinhos de Vento of Porto Alegre, one of Brazil’s leaders in health care delivery and innovation.

28 Aug 2013

New research focuses on perfectionism to improve treatment for adolescent anorexia

Reducing ‘perfectionistic’ thinking as a way to improve treatment for adolescent anorexia, is the focus of new research by Griffith University.

28 Aug 2013

Researchers suggest new therapeutic target for brain tumor

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas — the most common form of brain tumor — suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Health Union publishes RA in America 2013 survey results

Health Union, LLC announced today that it has published detailed results from the "RA in America 2013" survey on its newly launched website http://RheumatoidArthritis.Net. The survey covered a broad array of topics impacting people with Rheumatoid Arthritis (also called RA), and was taken by 1,055 respondents making it one of the largest of its kind conducted with RA patients in the United States.

28 Aug 2013

First Edition: August 28, 2013

Today's headlines include reports about the vote by Michigan lawmakers to expand Medicaid.

28 Aug 2013

Kessler Foundation scientist evaluates virtual reality office task in participants with MS and TBI

Denise Krch, Ph.D., research scientist for Traumatic Brain Injury Research at Kessler Foundation, presented "Pilot results from a virtual reality executive function task," at the International Conference on Virtual Rehabilitation. In the pilot study, Dr. Krch evaluated the Assessim Office, a virtual reality office task, in participants with multiple sclerosis and TBI.

28 Aug 2013

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Aug 2013

Keck Foundation awards $2M grant to UCLA scientists to improve quality of donor livers

A team of scientists from the UCLA Departments of Surgery and Pathology and Laboratory Medicine have been awarded a three-year, $2 million grant from the W.M. Keck Foundation to fund research aimed at increasing the quality of donor livers.

28 Aug 2013

URI professor studies rare hereditary disorder Fanconi anemia in children

When 2-year-old Logan Stevenson served as best man at his parents' wedding just days before he died of a rare genetic disorder, it drew international attention to a disease about which few people had ever heard. Hearing about Logan's story added another level of urgency to the research being conducted by University of Rhode Island Associate Professor Niall Howlett.

28 Aug 2013

Use of antipsychotics down among nursing home residents

A two-year effort by the federal government and the nursing-home industry has reduced the use of powerful antipsychotic drugs among elderly nursing-home residents, but the decline fell short of the program's goal, according to U.S. officials (Lagnado, 8/26).

28 Aug 2013

Researchers develop ddPCR technology to quantify rejection biomarker in organ transplant injury

A recently reported blood test for the early detection of organ transplant injury could enable more timely therapeutic intervention in transplant patients and thus help to avoid longer term damage. As described by scientists at the University Medical Center G-ttingen and Chronix Biomedical, a molecular diagnostics company, the new method uses Bio-Rad Laboratories' Droplet Digital PCR (ddPCR-) technology to overcome the obstacles of earlier tests, which were both time-consuming and costly.

28 Aug 2013

Study shows ABL kinases have enhanced expression and activity in CML

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to be associated with a genetic abnormality, known as the Philadelphia Chromosome, which 95% of all CML patients carry in their cells.

28 Aug 2013

Infant rotavirus vaccination reduced severe gastroenteritis among U.S. children

"Implementation of infant rotavirus vaccination in 2006 has substantially reduced the burden of severe gastroenteritis among U.S. children younger than 5 years," write Paul A. Gastanaduy, M.D., M.P.H., of the Centers for Disease Control and Prevention, Atlanta, and colleagues. "Whether indirect protection (due to reduced transmission of rotavirus) extends to adults remains unclear."

28 Aug 2013

UTHealth researchers find cause for rare type of bleeding disorder

Fifteen years ago, a hematologist came to Dianna Milewicz, M.D., Ph.D., with a puzzle: Multiple generations of an East Texas family suffered from a moderately severe bleeding disorder, but it wasn't hemophilia.

28 Aug 2013

Viewpoints: Sen. Cruz's strategy and a looming deadline; Michigan republicans face key test

Mr. Cruz also acknowledged that he does "not have the votes right now" to force a shutdown. At least 41 Senators need to play along, and, so far, only 13 have signaled their commitment to the cause. But the senator would only go so far in accepting reality.

28 Aug 2013

Memorial Sloan-Kettering Cancer Center announces new on-site broadcast studio and pressroom

Memorial Sloan-Kettering Cancer Center today unveiled a new pressroom for journalists with enhanced features such as embargoed content for registered users and "trending topics" - a continually updated listing of story ideas and available experts to comment on the latest health news headlines.

28 Aug 2013

Dr. Cecilia Lindgren receives the first Leena Peltonen Prize for Excellence in Human Genetics

The first Leena Peltonen Prize for Excellence in Human Genetics was awarded to Dr. Cecilia Lindgren for her work on applying genetics and genomics to dissect the etiology of type 2 diabetes, obesity and fat distribution.

28 Aug 2013

UW researchers perform first noninvasive human-to-human brain interface

University of Washington researchers have performed what they believe is the first noninvasive human-to-human brain interface, with one researcher able to send a brain signal via the Internet to control the hand motions of a fellow researcher.

28 Aug 2013

Research shows specific form of memory associations is encoded in cerebral cortex

'Where' and 'how' memories are encoded in a nervous system is one of the most challenging questions in biological research. The formation and recall of associative memories is essential for an independent life. The hippocampus has long been considered a centre in the brain for the long-term storage of spatial associations.

28 Aug 2013

Research News and Research

Alzheimer’s drug trial: an interview with Geoffrey Kempler, Chairman & CEO Prana Biotechnology

JHI signs agreement with HMV to enhance clinical care, patient safety and nursing education

New research focuses on perfectionism to improve treatment for adolescent anorexia

Researchers suggest new therapeutic target for brain tumor

Health Union publishes RA in America 2013 survey results

First Edition: August 28, 2013

Kessler Foundation scientist evaluates virtual reality office task in participants with MS and TBI

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

Keck Foundation awards $2M grant to UCLA scientists to improve quality of donor livers

URI professor studies rare hereditary disorder Fanconi anemia in children

Use of antipsychotics down among nursing home residents

Researchers develop ddPCR technology to quantify rejection biomarker in organ transplant injury

Study shows ABL kinases have enhanced expression and activity in CML

Infant rotavirus vaccination reduced severe gastroenteritis among U.S. children

UTHealth researchers find cause for rare type of bleeding disorder

Viewpoints: Sen. Cruz's strategy and a looming deadline; Michigan republicans face key test

Memorial Sloan-Kettering Cancer Center announces new on-site broadcast studio and pressroom

Dr. Cecilia Lindgren receives the first Leena Peltonen Prize for Excellence in Human Genetics

UW researchers perform first noninvasive human-to-human brain interface

Research shows specific form of memory associations is encoded in cerebral cortex

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