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Groundbreaking research on type 1 congenital myotonic dystrophy

Each year, the parents of an estimated one in 20,000 newborns are shocked to learn their child has type 1 congenital myotonic dystrophy (CDM1), a progressive and crippling genetic disorder.

24 May 2007

Brca2 gene prevents medulloblastoma

Investigators at St. Jude Children's Research Hospital have gained some of the first major insights into how certain genes known to prevent cancer also guide the normal development of the nervous system before birth and during infancy by repairing DNA damage.

22 May 2007

Parkin protein protects neurons from stress induced cell death

Parkinson’s disease, also known as shaking palsy, is one of the most frequent diseases of the nervous system.

22 May 2007

Treatment for enterotoxin B exposure

A research team led by the University of Illinois has developed a treatment for exposure to enterotoxin B, a noxious substance produced by the Staphylococcus aureus bacterium.

22 May 2007

Scientists develop method to track immune system enzyme in live animals

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.

18 May 2007

Computer science sheds light on animal development

By applying the techniques of computer engineering to a mechanistic diagram describing the development of the Nematode C. elegans, a group of researchers in Switzerland has been able to tease out what laboratory experiments have not how and when the crucial cross-talk between cellular signaling pathways takes place in order to determine the fates of individual cells.

18 May 2007

Promoter hypermethylation is common in breast cancer

Cancer epidemiologists at the University at Buffalo have identified specific genes that are most likely to become cancer promoters when exposed to a process called DNA promoter hypermethylation.

17 May 2007

Gene p53 thought to assist chemotherapy may help cancer thrive

A gene thought to be essential in helping chemotherapy kill cancer cells, may actually help them thrive.

16 May 2007

Cells that cause Ewing's sarcoma identified

Inserm researchers at the Institut Curie have identified the cells that cause Ewing’s sarcoma.

16 May 2007

Indonesia demands 'a fair go' for poor countries over bird flu vaccines

Indonesia has taken the lead in demanding that poor countries have equal access to bird flu vaccines.

15 May 2007

Specific genes identified that are most likely to become cancer promoters when exposed to DNA promoter hypermethylation

Hypermethylation is a process that causes genes that promote normal cell growth to produce proteins that cause malignant behavior, or unregulated cell growth. Until now, data has been very limited regarding the mechanism and causes of hypermethylation, especially for hypermethylation in breast cancer.

15 May 2007

Bird flu strikes again in Indonesia - death toll now 76

Health officials say two sets of tests have confirmed the woman died of bird flu, she was hospitalised in Medan, North Sumatra on May 8th with fever and respiratory problems and died four days later.

15 May 2007

Oncolytic viruses deliver a knockout punch to cancers

New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers.

11 May 2007

Adult bone marrow stem cells may help cure certain genetic eye diseases

Scientists have completed a study using mice which showed that bone marrow stem cells can switch roles and produce keratocan, a natural protein involved in the growth of the cornea, the transparent, outer layer of the eyeball.

11 May 2007

New understanding of ubiquitylation

It turns out there's more than one way to skin a gene. New research from Rockefeller University suggests that two closely related DNA unpackaging mechanisms may not work the way scientists thought.

10 May 2007

Opossum DNA provides new insight into natural selection

Study of the DNA of a South American marsupial called the opossum has revealed that a gene's location influences whether or not it is likely to gather changes that could lead to disease.

10 May 2007

Low frequency of resistance to Tamiflu confirmed

New data published by the World Health Organisation (WHO) has confirmed a low frequency of resistance to Tamiflu (oseltamivir) over 3 influenza seasons (2003:2006).

10 May 2007

Researchers discover genetic 'shut down' trigger in healthy immune cells

A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers.

10 May 2007

Researchers watch repair proteins arrive around DNA breaks

Investigators at St. Jude Children's Research Hospital had a molecule's eye view of the human cell's DNA repair kit as it assembled on a double-strand break to link together the broken ends.

10 May 2007

Bristol-Myers Squibb collaborates with Isis Pharmaceuticals

Bristol-Myers Squibb Company and Isis Pharmaceuticals have announced a collaboration to discover, develop and commercialize novel antisense drugs targeting proprotein convertase subtilisin kexin 9 (PCSK9) for the prevention and treatment of cardiovascular disease.

10 May 2007