Antigen News and Research

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New insights into how the circadian clock influences T cell responses to vaccination

Research by RCSI University of Medicine and Health Sciences has provided new insights into the mechanism behind how our circadian 24-hour body clock influences our immune response to vaccines, depending on the time of day.

5 Dec 2022

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Researchers developed an mRNA technology-based vaccine candidate against the monkeypox virus and evaluated its immunogenicity in animal models.

5 Dec 2022

Hepatitis B virus haplotype number is a predictive marker of functional cure during antiviral therapies

Patients with a lower hepatitis B virus haplotype number are more likely to achieve a functional cure with chronic hepatitis B treatment.

4 Dec 2022

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

Lipid nanoparticle (LNP)-based messenger ribonucleic acid (mRNA) vaccines have recently emerged as a promising strategy for the prevention and treatment of cancers, as well as infectious diseases.

4 Dec 2022

SARS-CoV-2 Omicron infections pose long-COVID risks despite reduced severity

researchers compared the post-coronavirus disease complaints and symptoms in individuals infected with the SARS-CoV-2 Omicron variant with those in individuals with Delta variant infections to understand whether the long-term complaints after Omicron infections are similar to those in infections with other SARS-CoV-2 variants.

2 Dec 2022

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

In this special supplement to the Journal of Parkinson's Disease, "The Immune System in Parkinson's Disease," experts highlight the latest research breakthroughs on the links between immune activation and neuroinflammation and Parkinson's disease (PD) and discuss the challenges and novel therapeutic strategies targeting the immune system with the hope of reducing or reversing neurodegeneration.

1 Dec 2022

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Scientists at Scripps Research have reported success in initial tests of a new, nanotech-based strategy against autoimmune diseases.

1 Dec 2022

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers mutated the SARS-CoV-2 spike protein's trimeric structure to design a novel prefusion S antigen, S2D14.

1 Dec 2022

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, has globally infected more than 639 million individuals and claimed over 6.6 million lives. Despite the rapid commencement of COVID-19 vaccination programs in most countries across the world, the virus has remained in circulation.

30 Nov 2022

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Researchers elucidated pan-sarbecovirus immune protection mechanisms by utilizing a Venezuelan equine encephalitis virus-vectored vaccine panel that covered bat strains to human strains.

30 Nov 2022

Study identifies risk factors that increase Black men's susceptibility to early-onset prostate cancer

A family history of cancer and genetic variants that might be inherited appear to be important risk factors for Black men diagnosed with early-onset prostate cancer, a study involving Duke Health researchers has found.

29 Nov 2022

What genes are associated with asthma exacerbations?

In a new study, researchers reviewed the genomics, transcriptomics, and epigenetics of asthma exacerbations (AEs).

29 Nov 2022

Small CDC study looks at SARS-CoV-2 viral shedding in vaccinated and unvaccinated

A new Centers for Disease Control and Prevention (CDC) study published in the Vaccine journal aimed to analyze the viral shedding and conversion timeline of SARS-CoV-2 infected people from exposure to infection and onset of symptoms during a period of Delta outbreak in a federal prison in Texas.

28 Nov 2022

Antigen News and Research

New insights into how the circadian clock influences T cell responses to vaccination

Researchers develop a polyvalent lipid nanoparticle mRNA vaccine against Monkeypox virus

Hepatitis B virus haplotype number is a predictive marker of functional cure during antiviral therapies

Researchers develop potent yet low-inflammatory mRNA cancer vaccine vectors

SARS-CoV-2 Omicron infections pose long-COVID risks despite reduced severity

New evidence on the links between immune activation and neuroinflammation and Parkinson's disease

New, nanotech-based strategy could enable safe, long-term treatment for autoimmune diseases

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Fragment crystallizable receptor-effector functions as a key correlate for pan-sarbecovirus vaccine development

Study identifies risk factors that increase Black men's susceptibility to early-onset prostate cancer

What genes are associated with asthma exacerbations?

Small CDC study looks at SARS-CoV-2 viral shedding in vaccinated and unvaccinated

Could mRNA vaccines triumph over other viral infections in humans and domestic animals?

Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

The frequency, magnitude, and longevity of natural antibody responses against nine P. vivax vaccine candidate proteins

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

Glycan signatures in rheumatic diseases and their associated functional implications

New technologies and recent advances in the study of T cells and T-cell epitope discovery in food allergy research

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