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Elevated uric acid levels may contribute to severe malaria outcomes in children

Indiana University School of Medicine researchers and their collaborators in Uganda at the Makerere University School of Medicine have uncovered a significant connection between elevated uric acid levels and life-threatening outcomes in children with severe malaria.

27 Jan 2025

Researchers discover link between protein aggregation and bacterial dormancy

Researchers at the VIB-KU Leuven Center for Microbiology and the VIB-KU Leuven Center for Brain & Disease Research revealed a mechanism involving protein aggregation that allows bacteria to enter a dormant state, a phenomenon that is associated with the persistence of infections and the challenge of antibiotic resistance.

27 Jan 2025

Mapping the human virome to improve disease prevention and treatment

You, my friend, are what scientists call a "holobiont"- an organism made up of human cells and the multiplicity of microscopic species living inside you and on your body.

24 Jan 2025

New compound V-161 offers hope in the fight against antibiotic-resistant bacteria

V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.

23 Jan 2025

Lean red meat in balanced diet supports gut and heart health, study reveals

A recent study from Purdue University scientists reveals following a consistent dietary pattern that features lean red meat can contribute to gut microbiota balance and support cardiovascular health.

23 Jan 2025

New discovery sheds light on how bacteria use plasmids to build resistance

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs.

23 Jan 2025

New $20 million NIH grant aims to uncover the secrets of the human virome

Unlocking knowledge about the vast and varied collection of viruses that live in and on our bodies is the goal of a $20 million grant from the Common Fund of the National Institutes of Health (NIH) to researchers, including a team at UTHealth Houston.

23 Jan 2025

Non-industrialized diet improves health and reduces disease risk

Researchers have found that a newly developed diet inspired by the eating habits of non-industrialised societies can significantly reduce the risk of a number of chronic diseases – and are to share recipes with the public.

23 Jan 2025

Study reveals how gut bacteria influence immune cell training and inflammation

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes-modifications that alter gene activity without affecting DNA sequence-in the stem cells that give rise to immune cells.

22 Jan 2025

How gut microbiota impacts childhood obesity

Gut microbiota plays a critical role in childhood obesity by influencing energy metabolism, inflammation, and appetite regulation, with emerging therapeutic strategies like probiotics, dietary interventions, and fecal microbiota transplantation showing promise.

21 Jan 2025

Study reveals biotin’s potential to mitigate manganese-induced brain damage

While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues.

21 Jan 2025

The science of silk fibroin and chitosan: Techniques for biomaterials analysis

An interview on how advanced techniques can be used to enhance silk fibroin and chitosan for drug delivery applications.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 21 Jan 2025

Symbiosis and horizontal gene transfer shape leaf beetle evolution

With more than 50,000 described species, the leaf beetle family is distributed worldwide and represents about a quarter of the species diversity of all herbivores.

20 Jan 2025

Inflammation in the gut could explain gastrointestinal problems in psoriasis patients

People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research at Uppsala University.

20 Jan 2025

Manuka vs. Ohia Lehua honey: Study reveals key antioxidant differences and health benefits

Study compares the antioxidant properties of Manuka honey (MH) and Ohia Lehua honey (OLH), revealing that MH contains ten times more phenolic content, while OLH demonstrates superior in vivo antioxidant activity by reducing oxidative stress and enhancing antioxidant capacity.

19 Jan 2025

Cigarette smoke alters immune cell function in the lungs

Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory illnesses is incomplete, which has severely hampered the development of effective treatments.

17 Jan 2025

The diverse immunological functions of megakaryocytes

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts.

17 Jan 2025

New study links cervicovaginal microbiome to increased risk of Chlamydia infections

The cervicovaginal microbiome's role in Chlamydia infections underscores the need for molecular classification to enhance prevention and treatment strategies.

17 Jan 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025

Study reveals high prevalence of Lyme disease bacteria in Northeast ticks

Across most of the Northeast, getting bitten by a blacklegged tick- also called a deer tick - is a risk during spring, summer, and fall. A new Dartmouth study, published in Parasites and Vectors, finds that 50% of adult blacklegged ticks carry the bacteria that causes Lyme disease while 20% to 25% of the younger (nymph) blacklegged ticks carry the bacteria.

17 Jan 2025