Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Celgene announces positive data from its apremilast Phase IIb study for plaque-type psoriasis

Celgene Corporation announced clinical data from an investigational Phase IIb, double-blind, placebo-controlled study of apremilast (CC-10004) in patients with moderate-to-severe plaque-type psoriasis (PSOR-005). This was a 352-patient, multi-center study in which patients received either 10mg, 20mg or 30mg of apremilast twice per day (BID), or placebo.

15 Dec 2009

ProChon Biotech announces expansion of BioCart Cartilage Regeneration System study

ProChon Biotech, Ltd., an innovator of tissue regenerative technologies that are being developed to relieve pain and restore the mobility and quality of life for sufferers of articular cartilage injuries, today announced a significant expansion of its clinical study of the BioCart™ Cartilage Regeneration System.

15 Dec 2009

Musical greeting cards can pose danger for children

While musical holiday cards are a lot of fun, Their batteries pose a danger to little ones. Kids swallow them and stick them in their ears and nose, A health problem this does pose. The Montreal Children's Hospital doesn't mean to preach But please keep these batteries out of reach.

14 Dec 2009

Genentech and Biogen Idec report positive outcome from ocrelizumab-MTX combination study in RA

Genentech, Inc. a wholly owned member of the Roche Group, and Biogen Idec announced today a Phase III study (STAGE) of the investigational humanized anti-CD20 monoclonal antibody ocrelizumab given in combination with methotrexate (MTX) met its primary endpoint of improving signs and symptoms (as measured by American College of Rheumatology or ACR20 response) in rheumatoid arthritis (RA) patients who had an inadequate response to MTX at both 24 and 48 weeks.

11 Dec 2009

Dermal stem cells may be useful for treating diabetic ulcers and neurological disorders

Scientists have discovered a new type of stem cell in the skin that acts surprisingly like certain stem cells found in embryos: both can generate fat, bone, cartilage, and even nerve cells.

10 Dec 2009

UC Davis receives NFL grant to study innovative ways for knee repair

NFL Charities, the charitable foundation of the National Football League, has awarded a grant of $125,000 to UC Davis for research on new ways to repair injured knees.

10 Dec 2009

Novo A/S implement 10b5-1 trading plan for open market purchases of BioMimetic common stock

BioMimetic Therapeutics, Inc. and Novo A/S announced that on December 8, 2009, Novo A/S implemented a 10b5-1 trading plan, providing for open market purchases of BioMimetic common stock. Any transactions involving the Company's securities under the plan will be reported and disclosed as required by applicable securities laws.

9 Dec 2009

Patients with recurrent shoulder dislocations may benefit from new surgical technique

The shoulder is the most commonly dislocated joint in the human body, occurring most often in young, athletic people. New research from the University of Michigan Health System shows patients who have recurrent shoulder dislocations may benefit from surgical reconstruction using cadaver bone and cartilage to essentially 'sculpt' a new shoulder.

8 Dec 2009

Biogen Idec's BG-12 achieves key milestones in clinical trials for MS and RA

Biogen Idec today announced that its oral compound BG-12 (dimethyl fumarate) achieved key milestones in clinical trials for multiple sclerosis (MS) and rheumatoid arthritis (RA).

8 Dec 2009

First patient treated in Carticept Medical's Cartiva SCI study

Carticept Medical, Inc., a developer of innovative products for the treatment of cartilage injuries and osteoarthritis, today announced that the first patient has been treated in an international, multi-center study of the Company's Cartiva Synthetic Cartilage Implant (SCI). The study aims to determine the effectiveness of Cartiva SCI in comparison to arthrodesis (joint fusion), the current standard of care, for reducing the debilitating pain associated with osteoarthritis of the first metatarsophalangeal (MTP) joint.

4 Dec 2009

Study on the genetics of osteoarthritis

Interleukin Genetics, Inc. and NYU Langone Medical Center announced findings from a study performed in collaboration with Duke University on the genetics of osteoarthritis have been published this week in the "Online First" version of the Annals of Rheumatic Diseases and is available at http://ard.bmj.com/cgi/rapidpdf/ard.2009.113043v1.pdf.

2 Dec 2009

European Patent Office grants patent EP1392642 for 4SC AG's lead auto-immune compound

4SC AG, a drug discovery and development company, today announced that the European Patent Office has granted patent EP1392642, which covers its lead auto-immune compound 4SC-101.

1 Dec 2009

CCII capsules offer safe and effective treatment for rheumatoid arthritis

Chicken collagen can provide relief from rheumatoid arthritis (RA) symptoms. A randomised, controlled trial, published in BioMed Central's open access journal Arthritis Research & Therapy, has found that Chicken type II collagen (CCII), a protein extracted from the cartilage of chicken breast, is a safe and effective treatment for RA.

1 Dec 2009

$Stem cell technology for rapid healing of complicated bone fractures$

Stem cell technology for rapid healing of complicated bone fractures

A novel technology involving use of stem cells, developed by Hebrew University of Jerusalem researchers, has been applied to provide better and rapid healing for patients suffering from complicated bone fractures.

30 Nov 2009

Prevalence of osteoarthritis continues to rise; OA expenses nearly 100% higher for women than men

Osteoarthritis (OA), a highly prevalent disease, raised aggregate annual medical care expenditures in the U.S. by $185.5 billion according to researchers from Stony Brook University. Insurers footed $149.4 billion of the total medical spend and out-of-pocket (OOP) expenditures were $36.1 billion (2007 dollars). Results of the cost analysis study are published in the December issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology.

30 Nov 2009

High levels of physical activity may damage knees and increase risk for osteoarthritis

Middle-aged men and women who engage in high levels of physical activity may be unknowingly causing damage to their knees and increasing their risk for osteoarthritis, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

30 Nov 2009

Researchers find causes for patellofemoral pain syndrome

From professional athletes to weekend warriors, the condition known as "runner's knee" is a painful and potentially debilitating injury suffered by millions of people - although until now, it has been unclear just what causes it.

24 Nov 2009

Canadian Arthritis Network to host 2009 Annual Scientific Conference in Vancouver

People with arthritis and leading Canadian and international researchers will share the stage under the theme "Decoding Arthritis - A Joint Effort" when the Canadian Arthritis Network (CAN) hosts its 2009 Annual Scientific Conference beginning tonight, in Vancouver, BC.

19 Nov 2009

OA panel develops a consensus of the optimal exogenous HA treatment using BioRestorative Profiling

A panel of osteoarthritis (OA) key opinion leaders has developed a consensus of the optimal exogenous hyaluronic acid (HA) treatment. This consensus was achieved by utilizing what the experts referred to as BioRestorative(TM) Profiling. This profiling examines HAs on the basis of their mimicking the body's natural HA.

19 Nov 2009

Pre-clinical data of GM1485 to be presented by GliaMed

GliaMed, Inc., a development stage biopharmaceutical company, today announced that Dr. David Weinstein, chief scientific officer and company founder, will present pre-clinical data demonstrating acceleration of wound healing through the in vivo induction and recruitment of stem cells at the Stem Cells USA & Regenerative Medicine Congress in Washington, D.C.

18 Nov 2009

Cartilage News and Research

Further Reading

Celgene announces positive data from its apremilast Phase IIb study for plaque-type psoriasis

ProChon Biotech announces expansion of BioCart Cartilage Regeneration System study

Musical greeting cards can pose danger for children

Genentech and Biogen Idec report positive outcome from ocrelizumab-MTX combination study in RA

Dermal stem cells may be useful for treating diabetic ulcers and neurological disorders

UC Davis receives NFL grant to study innovative ways for knee repair

Novo A/S implement 10b5-1 trading plan for open market purchases of BioMimetic common stock

Patients with recurrent shoulder dislocations may benefit from new surgical technique

Biogen Idec's BG-12 achieves key milestones in clinical trials for MS and RA

First patient treated in Carticept Medical's Cartiva SCI study

Study on the genetics of osteoarthritis

European Patent Office grants patent EP1392642 for 4SC AG's lead auto-immune compound

CCII capsules offer safe and effective treatment for rheumatoid arthritis

Stem cell technology for rapid healing of complicated bone fractures

Prevalence of osteoarthritis continues to rise; OA expenses nearly 100% higher for women than men

High levels of physical activity may damage knees and increase risk for osteoarthritis

Researchers find causes for patellofemoral pain syndrome

Canadian Arthritis Network to host 2009 Annual Scientific Conference in Vancouver

OA panel develops a consensus of the optimal exogenous HA treatment using BioRestorative Profiling

Pre-clinical data of GM1485 to be presented by GliaMed

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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