Clinical Trial News and Research

RSS

Electronic alerts could improve survival for patients with severe aortic stenosis

A new method of alerting clinical care providers holds promise for increasing treatment and improving survival for patients with severe aortic stenosis (AS), a valvular heart condition that can be deadly when left untreated.

23 Apr 2025

New vaccine targets sugar shield to protect against multiple coronaviruses

Sugar coatings aren't only for candies; they also help viruses, like the ones that cause COVID-19, hide from their hosts' immune system.

23 Apr 2025

Varenicline found to help teens and young adults quit vaping

A new study by investigators from Mass General Brigham showed that teens and young adults who took varenicline-an FDA-approved, twice-daily smoking cessation pill for adults-are more than three times as likely to successfully quit vaping compared to those who received only behavioral counseling. Results are published in JAMA.

23 Apr 2025

UCLA launches trial of wearable ADHD therapy for children exposed to alcohol in the womb

Researchers at UCLA Health are launching the first clinical trial to test whether a wearable device that delivers gentle nerve stimulation during sleep could ease ADHD symptoms in children with prenatal alcohol exposure.

22 Apr 2025

Walnut consumption linked to reduced inflammation and lower colon cancer risk

There are new findings out about the benefits of eating walnuts. Results from a UConn School of Medicine clinical trial on the cover of the April edition of the journal Cancer Prevention Research show walnuts improve systemic inflammation while also reducing colon cancer risk.

22 Apr 2025

Single psychedelic dose boosts long-term cognitive flexibility in mice

University of Michigan researchers have found that certain psychedelic compounds improve the brain’s ability to adapt and flexibly learn new concepts over long periods.

22 Apr 2025

New noninvasive method for early diabetes risk detection

The highs and lows of blood glucose aren't just an energy rollercoaster; they could be a key to detecting diabetes risk early and spare you a needle prick or two.

22 Apr 2025

New RNA-based blood test offers insight into cancer and tissue damage

Stanford Medicine researchers have developed a blood test capable of detecting cancers, the ways cancer resists treatments and tissue injury caused by non-cancerous conditions.

21 Apr 2025

iPS cell transplants show early promise for treating Parkinson's disease safely

In a first-of-its-kind human trial, researchers transplanted iPS-cell-derived dopaminergic progenitors into patients with Parkinson’s disease and observed promising motor improvements with no serious safety concerns over 24 months. The therapy showed increased dopamine synthesis without tumor formation or graft-induced dyskinesia.

21 Apr 2025

Hospitals can play key role in treating alcohol use disorder

Nearly 30 million adults in the United States experience alcohol use disorder (AUD), but the vast majority of people with this condition do not receive treatment.

21 Apr 2025

EEG monitoring helps reduce anesthesia use and improves pediatric recovery

Newly published results of a randomized, controlled clinical trial in Japan among more than 170 children aged 1 to 6 who underwent surgery, show that by using EEG readings of brain waves to monitor unconsciousness, an anesthesiologist can significantly reduce the amount of the anesthesia administered to safely induce and sustain each patient's anesthetized state.

21 Apr 2025

Natural supplement linked to slower biological aging and improved health

A new research paper was published in Aging (Aging-US) Volume 17, Issue 3, on March 14, 2025, titled "Effects of a natural ingredients-based intervention targeting the hallmarks of aging on epigenetic clocks, physical function, and body composition: a single-arm clinical trial."

21 Apr 2025

Muscle building unaffected by vegan or animal-based protein sources

A new study asked three questions about muscle protein synthesis in response to a nine-day diet and weight training regimen: First, does the source of protein - plant or animal-based - make any difference to muscle gain? Second, does it matter if total daily protein intake is evenly distributed throughout the day? And third, does a moderate but sufficient daily protein intake influence any of these variables? The answer to all three questions is "no," the researchers found.

21 Apr 2025

Monell study offers renewed hope for people living with Bardet-Biedl Syndrome

A Monell Chemical Senses Center study published this week in the Journal of Clinical Investigation offers renewed hope for individuals living with Bardet-Biedl Syndrome (BBS), a rare genetic disorder characterized by early-onset obesity, compulsive eating, and cognitive impairments.

18 Apr 2025

Beyond Ivy League, RFK Jr.’s NIH slashed science funding across states that backed Trump

The National Institutes of Health's sweeping cuts of grants that fund scientific research are inflicting pain almost universally across the U.S., including in most states that backed President Donald Trump in the 2024 election.

17 Apr 2025

Many stroke patients with carotid artery narrowing may avoid surgery, research shows

European research led by University College London (UCL), together with Amsterdam UMC and the University of Basel shows that a significant proportion of patients who suffer a stroke due to carotid artery narrowing can be treated with medication only.

16 Apr 2025

Transcranial magnetic stimulation and speech therapy boost language skills in stroke patients

Lucy Mulloor woke up one morning and realized something was terribly wrong. The 45-year-old single-mom could hear her two daughters in the kitchen but couldn't call out to them.

16 Apr 2025

New scoring system predicts stroke risk and reduces need for surgery

Researchers at UCL have tested a new scoring system to measure the risk of stroke in patients with narrowed arteries due to atherosclerosis, which could prevent unnecessary surgeries and stents.

16 Apr 2025

Stem cell therapy shows promise for treating advanced Parkinson's disease

A stem cell–based therapy initially developed at Memorial Sloan Kettering Cancer Center (MSK) may lead to a new treatment for advanced Parkinson's disease, according to results from a phase 1 clinical trial reported in Nature.

16 Apr 2025

Breakthrough method allows stem cell treatment for critically ill patients on ECMO

A multidisciplinary clinical team led by Professor Bernat Soria from the Institute of Bioengineering at the Miguel Hernández University of Elche (UMH, Spain) has developed a new method to deliver cell therapies in patients on extracorporeal membrane oxygenation (ECMO), a life support system used in cases of severe lung failure.

16 Apr 2025