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Scientists open door to significantly improved treatments for multiple sclerosis

A team of basic and clinical scientists led by the University of Montreal Hospital* Research Centre's Dr. Nathalie Arbour has opened the door to significantly improved treatments for the symptoms of Multiple Sclerosis.

20 Mar 2013

Researchers find white blood cells produce and eliminate RBCs

Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs).

18 Mar 2013

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Transplants of blood-forming stem cells from umbilical cord blood may be an effective alternative to transplants of matched donor bone marrow stem cells to treat children with a rare, debilitating disease known as Hurler's syndrome (HS), according to results of a study published online today in Blood, the Journal of the American Society of Hematology (ASH).

17 Mar 2013

Griffith University researchers discover critical weakness in leukaemic cells

Scientists at Griffith University's Institute for Glycomics and The Saban Research Institute of Children's Hospital Los Angeles have discovered a critical weakness in leukaemic cells, which may pave the way to new treatments.

14 Mar 2013

UNM scientists identify chemical compound that appears to control cell metastases

It's the spread of the original cancer tumor that kills most people. That's why cancer researchers vigorously search for drugs that can prevent metastases, the spread of cancer. The research team co-led by Angela Wandinger-Ness, PhD, and Larry Sklar, PhD, at the University of New Mexico Cancer Center has found a chemical compound that appears to control cell migration and adhesion, two important characteristics of metastatic cancer cells.

14 Mar 2013

Researchers determine way to predict and protect against new strains of flu virus

Researchers have determined a way to predict and protect against new strains of the flu virus, in the hope of improving immunity against the disease.

13 Mar 2013

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms.

13 Mar 2013

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013

APIC offers tips to stay infection-free

Beyond the obvious—steering clear of runny noses and hacking coughs—the Association for Professionals in Infection Control and Epidemiology (APIC) presents some other practical ways of staying infection-free.

8 Mar 2013

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Two brothers have been cured of their sickle cell disease at the University of Illinois Hospital & Health Sciences System using a relatively uncommon type of stem cell transplant that is performed without chemotherapy.

6 Mar 2013

Prompt antiretroviral therapy may help infants clear the HIV and achieve long-term remission

A team of researchers from Johns Hopkins Children's Center, the University of Mississippi Medical Center and the University of Massachusetts Medical School describe the first case of a so-called "functional cure" in an HIV-infected infant. The finding, the investigators say, may help pave the way to eliminating HIV infection in children.

4 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Women who are pregnant or using synthetic progesterone birth control injections have a conspicuous vulnerability to certain infections including malaria, Listeria, HIV, and herpes simplex virus.

2 Mar 2013

Early lymphoid progenitors thrive in an osteoblastic niche: Study

The Children's Medical Center Research Institute at UT Southwestern has deepened the understanding of the environment within bone marrow that nurtures stem cells, this time identifying the biological setting for specialized blood-forming cells that produce the infection-fighting white blood cells known as T cells and B cells.

25 Feb 2013

Distinct bone marrow niches can nurture different types of blood stem cells

In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells.

25 Feb 2013

International nonproprietary name “auriclosene” approved by WHO for NovaBay’s NVC-422

NovaBay® Pharmaceuticals, Inc. (NYSE MKT: NBY), a biotechnology company focused on addressing the large unmet therapeutic needs of the global anti-infective market with first-in-class compounds such as its proprietary Aganocides®, today announced that the World Health Organization (WHO) has approved the international nonproprietary name (INN) “auriclosene” (pronounced awr-rih-CLO-zeen) for the Company’s lead Aganocide® compound NVC-422.

21 Feb 2013

Imatinib can relieve and slow down progression of multiple sclerosis

A drug that is currently used for cancer can relieve and slow down the progression of the autoimmune disease multiple sclerosis (MS) in rats, according to a new study published in PLOS ONE.

21 Feb 2013

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.

20 Feb 2013

University of Louisville research team explores H1N1 outbreak

Just the mention of H1N1 can conjure up images of long lines of people waiting to be vaccinated, news reports of the severity of the pandemic and the count of the number of people who perished from the 2009-10 outbreak. However, some positives are coming forward.

20 Feb 2013

CCR1 and CCR5 receptors play a crucial role in atherosclerosis

Atherosclerosis is one of the commonest causes of death in modern societies. The condition is characterized by the build-up of fatty deposits called atherosclerotic plaques on the inner surfaces of arteries, which restrict, and may eventually cut off, blood flow. The deposits can also be dislodged from their site of origin and may then block major vessels in the heart or the brain, leading to life-threatening myocardial infarction or stroke.

20 Feb 2013

Leukocyte News and Research

Scientists open door to significantly improved treatments for multiple sclerosis

Researchers find white blood cells produce and eliminate RBCs

Umbilical cord blood stem cell transplants may be an effective alternative to treat Hurler's syndrome

Griffith University researchers discover critical weakness in leukaemic cells

UNM scientists identify chemical compound that appears to control cell metastases

Researchers determine way to predict and protect against new strains of flu virus

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

APIC offers tips to stay infection-free

Chemotherapy-free stem cell transplant shows promise for sickle cell disease

Prompt antiretroviral therapy may help infants clear the HIV and achieve long-term remission

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Synthetic progesterone birth control injections have vulnerability to certain infections: Research

Early lymphoid progenitors thrive in an osteoblastic niche: Study

Distinct bone marrow niches can nurture different types of blood stem cells

International nonproprietary name “auriclosene” approved by WHO for NovaBay’s NVC-422

Imatinib can relieve and slow down progression of multiple sclerosis

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

University of Louisville research team explores H1N1 outbreak

CCR1 and CCR5 receptors play a crucial role in atherosclerosis

Immunology eBook

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