Metabolites News and Research

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Researchers uncover a molecular mechanism to inhibit aggravation of colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system.

21 Sep 2021

COVID-19 and the gut-lung axis

A new study explores the hypothesis that stimulation of the gut could be responsible for the lung inflammation seen in COVID-19, triggered by SARS-CoV-2.

16 Sep 2021

Flavonoids can potentially help prevent COVID-19-induced diarrhea, study finds

A recent study published in Tropical Biomedicine determines whether flavonoids can help prevent diarrhea caused by SARS-CoV-2 infection.

15 Sep 2021

Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

Gut microbiome can help or confer resistance to weight loss

Gut microbiota influences the ability to lose weight in humans, according to new research. The findings were published this week in mSystems, an open-access journal of the American Society for Microbiology.

14 Sep 2021

Metabolic and immune markers as tools for risk stratification and monitoring in COVID-19

In a new study posted to the medRxiv* server scientists from Weil Cornell University and Stony Brook University in New York attempted to identify the metabolic and immune markers associated with severe COVID-19 disease using high-throughput targeted nuclear magnetic resonance (NMR) spectroscopy and high-dimensional flow cytometry. This will facilitate risk stratification, monitoring, and therapeutic interventions in COVID-19 patients.

14 Sep 2021

Study reveals blood metabolites associated with dementia

Scientists in Japan have identified metabolic compounds within the blood that are associated with dementia.

12 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

Study finds accumulation of common therapeutic drugs by gut bacteria

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the effectiveness of the drug.

8 Sep 2021

Researchers uncover underlying metabolic changes that are linked to COVID-19 severity

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

6 Sep 2021

New low-cost technique helps profile dynamic metabolic features from single isogenic cells

Researchers with the Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, have developed a fast, low-cost and high-throughput technique capable of profiling dynamic metabolic features from just one isogenic sample of cells.

1 Sep 2021

Discovery of new urinary biomarkers can boost the surveillance of synthetic drug abuse

A team of researchers from the National University of Singapore has come up with a new solution to boost the surveillance of designer drug abuse.

30 Aug 2021

Enzyme related to rattlesnake neurotoxin linked with COVID-19 infection severity

Study shows that an enzyme may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target.

25 Aug 2021

Study could provide a new therapeutic target to reduce COVID-19 mortality

An enzyme with an elusive role in severe inflammation may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target to reduce COVID-19 mortality, according to a study published in the Journal of Clinical Investigation.

25 Aug 2021

Study identifies a key molecular mechanism driving COVID-19 mortality

An enzyme with an elusive role in severe inflammation may be a key mechanism driving COVID-19 severity and could provide a new therapeutic target to reduce COVID-19 mortality.

24 Aug 2021

Researchers unravel pathomechanisms involved in Chronic Fatigue Syndrome

ME (Myalgic Encephalopathy), also known as Chronic Fatigue Syndrome (CFS), can be a debilitating disease. It frequently presents after an infection, and key features are long-lasting fatigue and worsening of symptoms after exertion.

23 Aug 2021

Researchers use residues in wastewater to study illicit drug consumption

At the start of the COVID-19 pandemic, stay-at-home orders and other restrictions drastically affected how people lived and worked, resulting in social isolation and economic instability. Now, researchers show that some people turned to a variety of drugs for relief. Using wastewater analysis, the team identified a spike in consumption of easily abused prescription opioids and anti-anxiety sedatives, while some illicit drug use plummeted, between March and June 2020.

23 Aug 2021

Study: Any form of exercise may not be the most effective prognostic tool for heart failure patients

While exercise therapy for heart failure (HF) patients with low heart function has been shown to be an effective prognostic tool, the level and format of exercise that yields optimal effects is still unclear.

19 Aug 2021

WVU researcher investigates inflammatory responses produced by exposure to chemical agents

Many of us face safety risks at work, but those serving in the military or working in law enforcement and industrial settings are at greater risk for dangerous chemical exposures.

18 Aug 2021

COVIDome Explorer online portal launched to accelerate COVID-19 research on a global scale

To further accelerate COVID-19 research on a global scale, investigators from the University of Colorado Anschutz Medical Campus have created a multidimensional dataset, known as the COVIDome dataset, derived from hospitalized COVID-19 patients versus negative controls.

17 Aug 2021