Neurodegenerative Diseases News and Research

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Novel biomarker effectively detects Alzheimer's disease before symptoms emerge

A newly developed radiotracer can measure increases in brain tau at least a year prior to the emergence of other symptoms.

15 Jun 2021

Researchers discover two new types of glial cells in the brain

Neurons, nerve cells in the brain, are central players in brain function. However, a key role for glia, long considered support cells, is emerging.

14 Jun 2021

DFG funds four collaborative research centers at Goethe University

Researching intricate geometric and arithmetic objects is the goal of the new Collaborative Research Centre Transregio 326 (TRR 326), coordinated by Goethe University.

11 Jun 2021

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

(BUSINESS WIRE)--QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reports.

9 Jun 2021

Weak brain signals may be an early warning sign of age-related neurodegenerative diseases

Weakened electrical signals in the brain may be an early warning sign of age-related neurodegenerative diseases such as Alzheimer's disease, suggests a study published today in eLife.

8 Jun 2021

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

Today's FDA approval of the monoclonal antibody Aduhelm (aducanumab) to treat patients with Alzheimer's disease reflects years of significant advances in Alzheimer's research. This is the first new Alzheimer's drug approved in 17 years and the first shown to modify the course of the disease, which FDA believes will lead to slowing of patients' cognitive decline.

8 Jun 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

The study findings reveal that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection results in abnormal modification of some lung proteins, which are subsequently transported to the brain via exosomes. In the brain, these modified lung proteins disrupt the normal functioning of proteins that are related to Parkinson’s disease.

7 Jun 2021

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

Researchers recently reviewed current knowledge on links between autophagy and coronaviruses and how this knowledge can be used to repurpose autophagy modulators as potential treatment options for COVID-19. The review is published in the journal Frontiers in Microbiology.

7 Jun 2021

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Our proteome is much bigger than our genome because one gene produces several variants of proteins called protein isoforms, whose disbalance is implicated in many diseases. c

5 Jun 2021

Newly identified protein could become a target for future cancer treatments

Researchers at the Francis Crick Institute have identified a protein that helps tumours evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

2 Jun 2021

Nanoscale coordination polymers show promise for efficient dopamine delivery in Parkinson's treatment

Parkinson's disease (PD) is a common neurodegenerative disorder caused by the death of dopaminergic neurons in a part of the brain (known as substantia nigra pars compacta), which leads to a deficit of dopamine (DA), one of the main neurotransmitters active in the central nervous system.

1 Jun 2021

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases, according to a study in fruit flies, and rat and human brain tissue, published today in eLife.

1 Jun 2021

New study to explore the health risks of nanoplastics

Nanoplastics--tiny plastic particles invisible to the naked eye--may exert an effect on nervous, immune, and reproductive systems of humans.

1 Jun 2021

Weaker association between brain activity and cerebrospinal fluid flow increases the likelihood of Alzheimer's disease

New imaging research shows that brain activity during sleep was less connected with cerebrospinal fluid flow in patients with Alzheimer's disease.

1 Jun 2021

Researchers use new technique to visualize brain tissue noninvasively

The way the human brain works remains, to a great extent, a topic of controversy. One reason is our limited ability to study neuronal processes at the level of single cells and capillaries across the entire living brain without employing highly invasive surgical methods. This limitation is now on the brink of change.

28 May 2021

Researchers identify structure of agent that causes Alzheimer's and Parkinson's diseases

Alzheimer's disease - also called dementia - where memory and cognitive functions gradually decline due to deformation and death of neurons, and Parkinson's disease that causes tremors in hands and arms impeding normal movement are major neurodegenerative diseases.

26 May 2021

Neurodegenerative Diseases News and Research

Novel biomarker effectively detects Alzheimer's disease before symptoms emerge

Researchers discover two new types of glial cells in the brain

DFG funds four collaborative research centers at Goethe University

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

Weak brain signals may be an early warning sign of age-related neurodegenerative diseases

FDA approves monoclonal antibody aducanumab for treating Alzheimer's patients

A single blood-based biomarker can help indicate underlying neurodegeneration

Researchers uncover molecular mechanism linking Parkinson’s disease with COVID-19

Study explores therapeutic potential of exploiting autophagy cascade against COVID-19

New bioengineered reporter system allows to follow protein isoform expression over time in live cells

Newly identified protein could become a target for future cancer treatments

Nanoscale coordination polymers show promise for efficient dopamine delivery in Parkinson's treatment

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

New study to explore the health risks of nanoplastics

Weaker association between brain activity and cerebrospinal fluid flow increases the likelihood of Alzheimer's disease

Researchers use new technique to visualize brain tissue noninvasively

Researchers identify structure of agent that causes Alzheimer's and Parkinson's diseases

New technology makes it easier to diagnose neurodegenerative diseases

New gel could be used as nasal spray for treating Parkinson's patients

Study demonstrates the negative effects of HERV activation on human brain development

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