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Hop supplements used by menopausal women are not likely to cause drug interactions

Hop-based dietary supplements that many women use to ease the night sweats and hot flashes commonly reported during menopause aren't likely to cause drug interactions, new research from Oregon State University's Linus Pauling Institute and College of Pharmacy shows.

19 May 2020

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

X-ray experiments demonstrate a new way to block the entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

19 May 2020

A minimally invasive approach to managing pain without opioids

Researchers at the University of Wisconsin (UW) are adopting a minimally invasive, safer approach to electrically treating pain directly at the source as part of the NIH Helping to End Addiction Long-term (HEAL) Initiative.

19 May 2020

Study highlights need to focus on medications that address clot formation

Earlier this week, the BBC reported that one-third of COVID-19 patients developed dangerous blood clots.

19 May 2020

Multi-institutional clinical trial sheds new light on non-responsive tumors

Over the last decade, enzalutamide and similar drugs have led to significant tumor control and increased survival time for men who have metastatic prostate cancer that continues to grow despite treatments to reduce male hormone levels.

19 May 2020

Study reports on clinical course of COVID-19 and risk factors in IBD patients

In an upcoming study to be published in Gastroenterology, researchers at the Icahn School of Medicine at Mount Sinai and the University of North Carolina School of Medicine report on the clinical course of COVID-19 and risk factors for adverse outcomes in a large cohort of patients with IBD collected through an international registry.

18 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

18 May 2020

Roswell Park team proposes possible new strategy for treating pancreatic cancer

A possible new strategy for treating pancreatic cancer highlights the promise of collaboration between experts in both precision medicine and immunology.

18 May 2020

Drugmakers tout COVID-19 vaccines to refurbish their public image

Johnson & Johnson researchers working on a vaccine against the coronavirus are "just like the heroes in the hospitals" fighting to save patients, J&J CEO Alex Gorsky said on the "Today" show a few weeks ago.

18 May 2020

COVID-19 may lead to thrombosis in the lungs and subsequently multi organ failure

COVID-19, the disease caused by SARS-CoV-2, not only may lead to severe pneumonia but also to thrombosis in the lungs and, subsequently, to multi organ failure involving kidneys, liver and pancreas.

18 May 2020

Avacta's SARS-COV-2 neutralizing Affimer reagents show therapeutic potential for COVID-19

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that several of the Affimer reagents recently generated for development of a point-of-care COVID-19 antigen saliva test have now also been shown to block the interaction between the virus’ spike protein and ACE2, a receptor on human cells that is key to the virus infection pathway.

From Avacta Life Sciences Ltd. 18 May 2020

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Boehringer Ingelheim today announced the acquisition of Northern Biologics Inc., a wholly owned subsidiary of Northern LP. By acquiring this entity, which focuses on therapeutic antibodies targeting the tumor microenvironment, Boehringer Ingelheim is now positioned at the forefront of the stromal biology space - an emerging area in cancer immunology.

From Boehringer Ingelheim International GmbH 18 May 2020

Research explores how human enzymes could be used to exacerbate COVID-19

Centenary Institute researchers have examined the critical role of human enzymes and the coronavirus in a newly published scientific review article that explores potential strategies for COVID-19 disease treatment and management.

18 May 2020

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

Takeda Pharmaceutical Company Limited today announced that the company will present data from its expanding oncology pipeline and established product portfolio at two upcoming virtual scientific congresses: the 56th Annual Meeting of the American Society of Clinical Oncology, May 29-31 and the 25th Virtual Congress of the European Hematology Association, June 11-14.

18 May 2020

A novel approach to predict heart damage in COVID-19 patients

Johns Hopkins researchers recently received a $195,000 Rapid Response Research grant from the National Science Foundation to, using machine learning, identify which COVID-19 patients are at risk of adverse cardiac events such as heart failure, sustained abnormal heartbeats, heart attacks, cardiogenic shock and death.

18 May 2020

Researchers investigate safety of convalescent plasma for COVID-19

The current pandemic of COVID-19 seems to be slowing down in various parts of the world, but is far from controlled, as incidence rates rise in new regions. In the absence of an effective vaccine or therapeutic drug, scientists have relied on supportive medical care to treat the sick.

17 May 2020

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

US researchers have published a proof of concept on the efficacy of human monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in laboratory conditions, as well as their pioneering use in a mouse model. The study is available on the preprint server bioRxiv*.

17 May 2020

COVID-19 patients at high risk for developing complications associated with blood clots

When researchers from the University of Colorado Anschutz Medical Campus, Aurora, used a combination of two specific blood-clotting tests, they found critically ill patients infected with Coronavirus Disease 2019 (COVID-19) who were at high risk for developing renal failure, venous blood clots, and other complications associated with blood clots, such as stroke.

15 May 2020

Therapy News and Research

Hop supplements used by menopausal women are not likely to cause drug interactions

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

X-ray experiments demonstrate a new way to block the entry of SARS-CoV-2

A minimally invasive approach to managing pain without opioids

Study highlights need to focus on medications that address clot formation

Multi-institutional clinical trial sheds new light on non-responsive tumors

Study reports on clinical course of COVID-19 and risk factors in IBD patients

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

Roswell Park team proposes possible new strategy for treating pancreatic cancer

Drugmakers tout COVID-19 vaccines to refurbish their public image

COVID-19 may lead to thrombosis in the lungs and subsequently multi organ failure

Avacta's SARS-COV-2 neutralizing Affimer reagents show therapeutic potential for COVID-19

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Research explores how human enzymes could be used to exacerbate COVID-19

Takeda to present oncology pipeline data at upcoming virtual scientific congresses

A novel approach to predict heart damage in COVID-19 patients

Researchers investigate safety of convalescent plasma for COVID-19

Study shows human monoclonal antibodies can effectively neutralize SARS-CoV-2

COVID-19 patients at high risk for developing complications associated with blood clots

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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