Genetic News and Research

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NETRF announces $3.5 million in research grants to improve neuroendocrine tumor treatment

The Neuroendocrine Tumor Research Foundation, Boston, MA, today announced $3.5 million in neuroendocrine tumor research grants to fund 12 projects around the world in pursuit of more precise treatments for this uncommon cancer affecting an estimated 171,000 Americans.

12 Feb 2020

Study provides new details about therapy-associated polyposis in childhood cancer survivors

In a paper published online today, Dana-Farber Cancer Institute researchers provide new details about a recently discovered condition in which childhood cancer survivors develop numerous colorectal growths called polyps despite not having a hereditary susceptibility to the condition.

12 Feb 2020

High testosterone in women ups risk for cancer, diabetes, and metabolic disease

Testosterone is a steroid hormone that triggers the development of male secondary sex characteristics. Though found mainly in men, the ovaries in women release small amounts of testosterone. When combined with estrogen, testosterone aids in the growth and repair of a woman's reproductive tissues.

12 Feb 2020

Unexpected findings could lead to new therapeutic intervention for ALS

A therapeutic intervention for amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, could be on the horizon thanks to unexpected findings by University of Arizona researchers.

11 Feb 2020

Age of puberty in girls the world over becoming lower

A new study on the age of initial breast development as the first sign of puberty in girls shows that over the last 40 years, this has come down by an average of 3 months per decade. The study is published in the journal Pediatrics.

11 Feb 2020

Accumulated brain protein affects genes in Alzheimer's disease

A new study published in February 2020 in the journal Cell Reports shows how the build-up of specific brain cell proteins are linked to altered gene expression that causes the symptoms of Alzheimer's disease (AD).

11 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020

DNA misfolding linked to heightened risk for Type 1 diabetes

It's known that genetics, or an inherited genome, is a major determinant of one's risk for autoimmune diseases, like Type 1 diabetes. In human cells, a person's genome--about six feet of DNA--is compressed into the micrometer space of the nucleus via a three-dimensional folding process.

11 Feb 2020

Major breakthrough in understanding how malaria parasite grows and multiplies

Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital clue in discovering how it has evolved, and how it can be stopped.

11 Feb 2020

UC research could help identify organ donors at risk of developing kidney disease

Kidney transplantation is the gold standard treatment for end-stage kidney disease and is associated with an advantage over dialysis in both survival and quality of life.

11 Feb 2020

A protein that plays key role in endometrial cancer growth discovered

The hormone estrogen plays many critical roles in men and women, in both healthy tissues and in cancer. In breast and gynecologic cancers, estrogen sends signals to tumors instructing the cancer cells to grow out of control.

11 Feb 2020

PolyU develops fully automated, rapid diagnostic platform for detecting respiratory infectious diseases

The Hong Kong Polytechnic University today announced the development of the world's most comprehensive automated multiplex diagnostic system (the System) which includes a fully automated machine and a multiplex full-screening panel for the point-of-care genetic testing of respiratory infectious disease including the 2019-nCoV.

11 Feb 2020

Study evaluates feasibility of using T'ai Chi to improve chronic low back pain in older adults

A new study evaluated the feasibility and acceptability of using T'ai Chi to improve chronic low back pain in adults over 65 years of age compared to health education and usual care.

11 Feb 2020

Taller body height in young men linked to lower risk of dementia in old age

Men who are taller in young adulthood, as an indicator of early-life circumstances, may have a lower risk of dementia in old age, suggests a study published today in eLife.

11 Feb 2020

Pioneering project on genomic edition through CRISPR/Cas9 to study early embryonic development

Characterization studies of early embryonic development are limited, mainly due to the lack of samples and the obvious legal and ethical limitations.

11 Feb 2020

Free radicals from immune cells linked to salt-sensitive hypertension

In salt-sensitive hypertension, immune cells gather in the kidneys and shoot out free radicals, heightening blood pressure and damaging this pair of vital organs, scientists report.

11 Feb 2020

Addressing the complexity of nasal tip contouring

The dramatic shift in how nasal tip surgery is being performed given changes in the intended goals and evolving techniques is highlighted in a Special Communication by and interview with Dean Toriumi, MD, published in the Official Journal of the American Academy of Facial Plastic and Reconstructive Surgery, Facial Plastic Surgery & Aesthetic Medicine, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

11 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

First artificial enzyme with non-biological catalytic sites created

A new study published in the journal Nature Catalysis on February 10, 2020, reports the creation of a new artificial enzyme from two components, both non-biological in origin. This event marks the first such successful biological catalyst to contain a non-biological active site. The study shows that this type of synergistic combination of an amino acid not found in nature with a copper-based catalyst is capable of powerful catalytic action, unlike most other artificial enzymes.

10 Feb 2020

New summary report highlights advances and challenges in small cell lung cancer research

In 2017, a group of lung cancer experts posed the question: "Can recent advances in tumor biology that have led to progress treating non-small cell lung cancer translate into improved outcomes for small cell lung cancer?"

10 Feb 2020

Genetic News and Research

NETRF announces $3.5 million in research grants to improve neuroendocrine tumor treatment

Study provides new details about therapy-associated polyposis in childhood cancer survivors

High testosterone in women ups risk for cancer, diabetes, and metabolic disease

Unexpected findings could lead to new therapeutic intervention for ALS

Age of puberty in girls the world over becoming lower

Accumulated brain protein affects genes in Alzheimer's disease

Macrophages migrate from the blood to attack brain tissue shortly after stroke

DNA misfolding linked to heightened risk for Type 1 diabetes

Major breakthrough in understanding how malaria parasite grows and multiplies

UC research could help identify organ donors at risk of developing kidney disease

A protein that plays key role in endometrial cancer growth discovered

PolyU develops fully automated, rapid diagnostic platform for detecting respiratory infectious diseases

Study evaluates feasibility of using T'ai Chi to improve chronic low back pain in older adults

Taller body height in young men linked to lower risk of dementia in old age

Pioneering project on genomic edition through CRISPR/Cas9 to study early embryonic development

Free radicals from immune cells linked to salt-sensitive hypertension

Addressing the complexity of nasal tip contouring

Finding a cure for canine gliomas may help find treatment for human brain cancer

First artificial enzyme with non-biological catalytic sites created

New summary report highlights advances and challenges in small cell lung cancer research

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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