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FDA approves Twinrix

GlaxoSmithKline has announced that the U.S. Food and Drug Administration (FDA) has approved Twinrix [Hepatitis A Vaccine (Inactivated) and Hepatitis B (Recombinant) Vaccine], for an accelerated dosing schedule that consists of three doses given within three weeks followed by a booster dose at 12 months.

4 Apr 2007

Effects of changing Paracetamol pack size regulations in UK

Fatal poisonings involving paracetamol (acetaminophen) fell after a law introduced in the UK restricted the number of tablets that could be sold across the counter.

4 Apr 2007

Cost-effectiveness analysis of variceal ligation vs. beta-blockers for primary prevention of variceal bleeding

Endoscopic variceal ligation is cost-effective relative to beta-blockers for the prevention of variceal bleeding in cirrhotic patients if quality of life-years are considered.

4 Apr 2007

NAFLD fibrosis score helps predict advanced fibrosis in patients with nonalcoholic fatty liver disease

Certain routine demographic, clinical, and laboratory values can be used to identify advanced fibrosis in patients with nonalcoholic fatty liver disease (NAFLD).

4 Apr 2007

Voluntary living liver donors should undergo a careful, but quick, workup

...and their desire for altruism should not be hampered by negativism from the transplant community, say the authors of a new study in the April issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS).

4 Apr 2007

Recognition for cancer researchers

World-class cancer researchers whose science has significantly contributed to progress in the fight against cancer will be recognized April 14-18, 2007, by the American Association for Cancer Research (AACR) at its 2007 Annual Meeting in Los Angeles, Calif.

3 Apr 2007

Researchers discover factor that controls blood sugar's manufacture in a novel way

Researchers have discovered a factor that controls blood sugar's manufacture in a novel way: by limiting the supply of its building blocks. The findings are reported in the April issue of the journal Cell Metabolism, published by Cell Press.

3 Apr 2007

H63D genetic defect linked to increased risk of stroke

One of the most common genetic defects passed on through families significantly increases a person's chance of having a stroke, according to a study published in the March 27, 2007, issue of Neurology?, the scientific journal of the American Academy of Neurology.

2 Apr 2007

$Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock$

Drug that mimics HDL does not reduce risk of death for heart attack patients with refractory shock

Patients with acute coronary syndromes (ACS), such as heart attack and recent-onset chest pain, remain at considerable risk of experiencing further serious cardiovascular problems despite improvements in care.

2 Apr 2007

Critical receptor in liver regeneration identified

In studies in mouse models, researchers at the University of California, San Diego (UCSD) School of Medicine have found that a cellular receptor involved in triggering cell death is also a necessary component of tissue repair and regeneration immediately following liver injury.

2 Apr 2007

Synthetic molecule helps detect heart attack in the making

A new bright spot in heart disease research may soon allow physicians to peer directly into patients' blood vessels and find dangerous cholesterol-filled plaques before they rupture and cause a heart attack.

2 Apr 2007

MIT MEMS device provides precise way to physically arrange cells

Now MIT researchers led by Sangeeta Bhatia, associate professor of electrical engineering and computer science at the Harvard-MIT Division of Health Sciences and Technology (HST) and Brigham and Women's Hospital, have solved the problem with a novel device.

2 Apr 2007

Reconstituted HDL may have some benefit in coronary atherosclerosis

Preliminary research suggests that use of reconstituted HDL may have some benefit in coronary atherosclerosis, according to a JAMA study published online March 26.

2 Apr 2007

New target for removing unwanted ammonia from the body

Thousands of people with liver and kidney disease die every year from too much ammonia in their blood, and scientists from the United States and Japan have found a possible solution.

2 Apr 2007

Regenerative medicine project taps into human stem cells

Researchers at the McKnight Brain Institute of the University of Florida have initiated a project to treat human brain and other diseases by plundering the secrets of regeneration from creatures with remarkable powers of self-renewal, such as salamanders, newts, starfish and flatworms.

2 Apr 2007

Estrogen improves host response after traumatic injury

Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage.

2 Apr 2007

Bone marrow stem cells used to regenerate healthy human liver tissue

For the first time, researchers have used adult bone marrow stem cells to regenerate healthy human liver tissue, according to a study published in the April issue of the journal Radiology.

1 Apr 2007

FDA approves Ceprotin to treat severe congenital protein C deficiency

The U.S. Food and Drug Administration (FDA) today licensed Ceprotin, the first biologic treatment for patients with a rare genetic defect that can cause a potentially life-threatening clotting disorder.

30 Mar 2007

Blueprint for cell, tissue and organ donation and transplantation

This week, at the second Global Consultation on Transplantation the World Health Organization (WHO) presented countries and other stakeholders with a blueprint for updated global guiding principles on cell, tissue and organ donation and transplantation.

30 Mar 2007

Cryoablation for kidney tumor patients shows promise

Mayo Clinic researchers report that freezing kidney tumors through percutaneous cryoablation shows promise for patients who are not good candidates for surgery.

30 Mar 2007