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Molecular mechanism in nerve fibers ensures rapid conductance of nervous system impulses

New research from the University of North Carolina at Chapel Hill School of Medicine describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses.

27 Jan 2011

AB Science initiates recruitment in masitinib phase 3 study in severe persistent asthma

AB Science SA, a pharmaceutical company specialising in the research, development and commercialisation of protein kinase inhibitors (PKIs), announced today the recruitment of the first patient in the phase 3 study evaluating masitinib in severe persistent asthma.

27 Jan 2011

Pfenex receives $3.1 million SAIC sub-contract to develop malaria antigen

Pfenex today announced that Science Applications International Corporation has awarded Pfenex a sub-contract valued at $3.1 million to help develop a robust, scalable, cGMP ready production process for large scale production of full length Circumsporozoite protein from Plasmodium falciparum.

27 Jan 2011

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

For 60 years, scientists have puzzled over the possibility of a hepatic osmoreceptor that influences blood pressure regulation. Now, researchers of the Max Delbr-ck Center for Molecular Medicine Berlin-Buch, the Experimental and Clinical Research Center of the MDC and Charit- and the Hannover Medical School appear to have made a breakthrough discovery.

27 Jan 2011

Avantra begins shipment of new Q400 Biomarker Workstation and Angio Qx BioChip Immunoassay

Avantra® Biosciences, a leading innovator in protein diagnostics, announced today their first shipments of the new Q400 Biomarker Workstation and the innovative Angio Qx™ BioChip Immunoassay.

27 Jan 2011

MGH investigators develop novel system to deliver growth factors to chronic wounds

Massachusetts General Hospital investigators have developed a novel system for delivery of growth factors to chronic wounds such as pressure sores and diabetic foot ulcers.

27 Jan 2011

Potential therapy to enhance memory and prevent loss of long-term memory

Researchers from Mount Sinai School of Medicine have identified a therapy that may enhance memory and prevent the loss of long-term memory. The research is published in the January 27th issue of Nature.

27 Jan 2011

Researchers develop anti-HIV gene therapy for rendering T-cells resistant to infection

An innovative genetic strategy for rendering T-cells resistant to HIV infection without affecting their normal growth and activity is described in a paper published in Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. The paper is available free online.

26 Jan 2011

Emergent BioSolutions initiates TRU-016 Phase Ib/II study for chronic lymphocytic leukemia

Emergent BioSolutions Inc. today announced the initiation of a Phase Ib/II study (16201) of TRU-016 for chronic lymphocytic leukemia (CLL). TRU-016 is a CD37-directed Small Modular ImmunoPharmaceutical (SMIP™) protein therapeutic in development for the treatment of B-cell malignancies. TRU-016 is being developed in collaboration with Abbott.

25 Jan 2011

NINDS awards AndroScience $3.8M cooperative translational research grant for Kennedy's Disease

AndroScience Corp., based in San Diego, California, announced receiving a $3.8 Million, 3-year milestone-driven, cooperative translational research grant from the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH).

25 Jan 2011

Octapharma supports development of 'Diagnosis and Management of von Willebrand Disease' CE supplement

An unrestricted grant from Octapharma USA supported the development of a Continuing Education (CE) initiative entitled the "The Diagnosis and Management of von Willebrand Disease," a program of the National Home Infusion Association (NHIA).

25 Jan 2011

Sanofi-aventis acquires world-wide license for ADC products

Oxford BioTherapeutics today announces that sanofi-aventis has acquired an exclusive world-wide license to one of OBT's internal preclinical antibody programs.

25 Jan 2011

p38-targeted compounds hold promise for Alzheimer's disease treatment

Linda J. Van Eldik, director of the University of Kentucky Sanders-Brown Center on Aging, has been awarded a $750,000 grant to further her research into a possible treatment for Alzheimer's disease. The grant is from the Edward N. And Della L. Thome Memorial Foundation, and was one of only eight Awards in Alzheimer's Disease Drug Discovery Research to be given in the U.S. in 2010.

25 Jan 2011

Human model of rare genetic disease reveals new clues to aging process

Scientists from A*STAR's Institute of Medical Biology (IMB) in Singapore and the University of Hong Kong's Department of Medicine have produced the world's first human cell model of progeria, a disease resulting in severe premature ageing in one in four to eight million children worldwide. This model has allowed them to make new discoveries concerning the mechanism by which progeria works.

25 Jan 2011

Researchers design engineered organ study the use of nanoparticles in breast cancer detection

Purdue University researchers have reproduced portions of the female breast in a tiny slide-sized model dubbed "breast on-a-chip" that will be used to test nanomedical approaches for the detection and treatment of breast cancer.

25 Jan 2011

Simple means of improving binding affinity of synbodies

Antibodies are watchdogs of human health, continuously prowling the body and registering minute changes associated with infection or disease with astonishing acuity. They also serve as biochemical memory banks, faithfully recording information about pathogens they encounter and efficiently storing this data for later use.

25 Jan 2011

Bax factor that promotes cell death is also involved in regulating mitochondria behavior

New research led by UC Davis scientists provides insight into why some body organs are more susceptible to cell death than others and could eventually lead to advances in treating or preventing heart attack or stroke.

24 Jan 2011

Blocking rogue gene may stop cancer spread: Study

In a new breakthrough British scientists have discovered a “rogue gene” which helps cancer spread around the body and add that this could mean specific therapy, if developed against the gene, could stop cancer spread.

24 Jan 2011

Breakthrough in understanding mechanisms behind hereditary alpha-1-antitrypsin deficiency

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have made a breakthrough in understanding the mechanisms behind the most severe form of hereditary emphysema and how protein treatments can improve the condition. The findings of this study may also lead to new treatments for patients with smoker's emphysema.

24 Jan 2011

Mystery of 'inactive' defensin solved

Under standard laboratory conditions, the human beta-defensin 1 (hBD-1), a human antibiotic naturally produced in the body, had always shown only little activity against microbes. Nevertheless the human body produces it in remarkable quantities.

24 Jan 2011

G Protein News and Research

Molecular mechanism in nerve fibers ensures rapid conductance of nervous system impulses

AB Science initiates recruitment in masitinib phase 3 study in severe persistent asthma

Pfenex receives $3.1 million SAIC sub-contract to develop malaria antigen

Researchers discover new sensory neurons that mediate BP and metabolism regulation in liver

Avantra begins shipment of new Q400 Biomarker Workstation and Angio Qx BioChip Immunoassay

MGH investigators develop novel system to deliver growth factors to chronic wounds

Potential therapy to enhance memory and prevent loss of long-term memory

Researchers develop anti-HIV gene therapy for rendering T-cells resistant to infection

Emergent BioSolutions initiates TRU-016 Phase Ib/II study for chronic lymphocytic leukemia

NINDS awards AndroScience $3.8M cooperative translational research grant for Kennedy's Disease

Octapharma supports development of 'Diagnosis and Management of von Willebrand Disease' CE supplement

Sanofi-aventis acquires world-wide license for ADC products

p38-targeted compounds hold promise for Alzheimer's disease treatment

Human model of rare genetic disease reveals new clues to aging process

Researchers design engineered organ study the use of nanoparticles in breast cancer detection

Simple means of improving binding affinity of synbodies

Bax factor that promotes cell death is also involved in regulating mitochondria behavior

Blocking rogue gene may stop cancer spread: Study

Breakthrough in understanding mechanisms behind hereditary alpha-1-antitrypsin deficiency

Mystery of 'inactive' defensin solved

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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