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Research reveals that large non-coding RNA in mammals play an important role in telomere maintenance

A team of researchers from The Wistar Institute have shown that a large non-coding RNA in mammals and yeast plays a central role in helping maintain telomeres, the tips of chromosomes that contain important genetic information and help regulate cell division. Since this RNA also facilitates the formation of DNA at telomeres-a process that can protect aging cells and destabilize tumor cells-manipulating its expression may be useful in treating cancer and other diseases.

1 Sep 2009

Tel Aviv University researcher devises mathematical formula for protecting the genetic privacy

Last year, after a published paper found serious security holes in the way DNA data is made publicly available, health institutes in the United States and across the world removed all genetic data from public access.

1 Sep 2009

Illumina delivers its first individual genome sequence to Dr. Hermann Hauser

Illumina, Inc. today announced that it has delivered Hermann Hauser’s genome sequence. Dr. Hauser, Partner, Amadeus Capital Partners Ltd, is the first consumer to purchase Illumina’s individual genome sequencing service working with his physician, Michael Nova, MD, of Pathway Genomics.

From Illumina, Inc. 31 Aug 2009

DSG finds place in the Inc. 500 list

The Inc. 500, which ranks the fastest growing U.S. privately held companies, announced that DSG reached No. 82 in the nation, making it the fastest growing privately held company in the Philadelphia area. As an Inc. 500 honoree, DSG shares a prestigious pedigree with such notable companies as Intuit, Microsoft, and Oracle.

31 Aug 2009

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing's sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene.

31 Aug 2009

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

Investigators at Hospital for Special Surgery, collaborating with researchers from other institutions, have contributed to the discovery that a gene called interferon regulator factor-8 (IRF-8) is involved in the development of diseases such as periodontitis (gum disease), rheumatoid arthritis and osteoporosis. The study, which will be published online August 30, ahead of print, in the journal Nature Medicine, could lead to new treatments in the future.

31 Aug 2009

Genetic variants on chromosome 9q may influence asthma development in Mexican children

Genetic variants in a region on chromosome 9q may influence asthma development in Mexican children, according to research published in the August 28 issue of the open-access journal PLoS Genetics.

28 Aug 2009

Albert Einstein College of Medicine receives $11.2 million NIH grant to study genes associated with longevity

The National Institutes of Health (NIH) has awarded Albert Einstein College of Medicine of Yeshiva University a five-year, $11.2 million grant to study the impact of damage to DNA on aging and disease. Research funded by this grant, and conducted by a consortium of scientists, could reveal the role of genome maintenance systems in delaying aging and will begin to explore novel interventions to maintain health in old age.

28 Aug 2009

NIH panel releases report on the pertinence of family health history information in improving health

Though most Americans are familiar with completing a questionnaire about their family health history when visiting health care providers, an independent panel was convened by the National Institutes of Health this week to critically assess exactly what we know and what we need to learn about how this process relates to improving health.

28 Aug 2009

Lakewood-Amedex to speed up development of its broad spectrum anti-influenza product into clinical studies

Lakewood-Amedex Inc., (L-A), the anti-infectives biopharmaceutical company developing a unique portfolio of anti-bacterial and anti-viral products including NuBiotics, a novel family of synthetic anti-bacterial compounds, and anti-viral products against hepatitis, HIV and influenza, announced today that it is accelerating development of its broad spectrum anti-influenza product into clinical studies.

27 Aug 2009

$201,339 grant offered to a professor for developing a database on enzyme functions

Since the advent of the Human Genome Project an explosion of data has sent the science world scrambling. There is a growing demand to fine-tune genomic codes, which list the "ingredients for life," but do not adequately explain how those ingredients function. A Rutgers University-Camden biochemist is addressing this knowledge gap through the creation of a database for quick "background checks" on all known enzyme functions. Thanks to a National Institute of Health grant, Peter Palenchar, an assistant professor of chemistry at Rutgers-Camden, will categorize decades-worth of scholarship on enzymes into a database, beginning with those that bind to molecules that contain adenosine.

27 Aug 2009

Mutations associated with prion diseases are sufficient to cause transmissible neurodegenerative disease

For the first time, Whitehead Institute researchers have shown definitively that mutations associated with prion diseases are sufficient to cause a transmissible neurodegenerative disease.

26 Aug 2009

University of Maryland researchers perform a genome-wide association study of ADP-stimulated platelet aggregation

Patients with a certain genetic variation who received the antiplatelet drug clopidogrel had a decreased platelet response to treatment and among those who had percutaneous coronary intervention (procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries) had an increased risk of having a cardiovascular event in the following year than patients who did not have this variant, according to a study in the August 26 issue of JAMA.

25 Aug 2009

Genome BC's research projects to determine efficient methods of liberating fermentable sugars from dead pine

In order to reduce the Province's greenhouse gas emissions, the BC Bioenergy Strategy is calling for greatly increased production of renewable biofuels such as ethanol, from biomass grown in BC. Two new research projects, largely funded by Genome BC, will help to answer these questions and unlock the valuable green energy found within BC's forests.

25 Aug 2009

Malaysian biotechnology industry expected to grow by revenue at an average rate of 15 percent per year

Malaysia's plans for its biotechnology sector remain ambitious even with the recent global meltdown. By 2020 the government envisages this sector will employ up to 160,000 people and will contribute to 5% of Malaysia's GDP.

25 Aug 2009

New technique developed to identify gene copy number variations

A research team led by Associate Professor Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL) has developed a sensitive and accurate way of identifying gene copy number variations (CNVs).

25 Aug 2009

Complete Genomics raises $45 million in private equity financing

Complete Genomics Inc., a third-generation human genome sequencing company, announced that it has raised $45 million in private equity financing and closed its Series D funding round with two new investors — Essex Woodlands Health Ventures and OrbiMed Advisors, LLC.

24 Aug 2009

Two key circuits for controlling the cell's ability identified by UCSF researchers

UCSF researchers have identified the two key circuits that control a cell's ability to adapt to changes in its environment, a finding that could have applications ranging from diabetes and autoimmune research to targeted drug development for complex diseases.

24 Aug 2009

More evidence that genes increase a smokers' risk of lung cancer

Cancer Research UK funded scientists have confirmed that inherited changes in certain regions of the genome can increase a smokers' risk of developing lung cancer lung cancer, and determine the type of lung cancer that develops. Their results were published in this week's edition of the journal Cancer Research*.

21 Aug 2009

Helicos Genetic Analysis System to aid Ontario Institute for Cancer Research scientists in the study of cancer genomics

Helicos BioSciences Corporation (NASDAQ: HLCS), a life science company focused on innovative genetic analysis technologies, today announced the placement of a Helicos™ Genetic Analysis System at the Ontario Institute for Cancer Research (OICR) with Drs. Tom Hudson and John McPherson.

20 Aug 2009

Genome News and Research

Research reveals that large non-coding RNA in mammals play an important role in telomere maintenance

Tel Aviv University researcher devises mathematical formula for protecting the genetic privacy

Illumina delivers its first individual genome sequence to Dr. Hermann Hauser

DSG finds place in the Inc. 500 list

Research reveals the reason why some patients with Ewing's sarcoma do not respond to chemotherapy

Study reveals that downregulation of IRF-8 gene causes gum diseases, arthritis and osteoporosis

Genetic variants on chromosome 9q may influence asthma development in Mexican children

Albert Einstein College of Medicine receives $11.2 million NIH grant to study genes associated with longevity

NIH panel releases report on the pertinence of family health history information in improving health

Lakewood-Amedex to speed up development of its broad spectrum anti-influenza product into clinical studies

$201,339 grant offered to a professor for developing a database on enzyme functions

Mutations associated with prion diseases are sufficient to cause transmissible neurodegenerative disease

University of Maryland researchers perform a genome-wide association study of ADP-stimulated platelet aggregation

Genome BC's research projects to determine efficient methods of liberating fermentable sugars from dead pine

Malaysian biotechnology industry expected to grow by revenue at an average rate of 15 percent per year

New technique developed to identify gene copy number variations

Complete Genomics raises $45 million in private equity financing

Two key circuits for controlling the cell's ability identified by UCSF researchers

More evidence that genes increase a smokers' risk of lung cancer

Helicos Genetic Analysis System to aid Ontario Institute for Cancer Research scientists in the study of cancer genomics

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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