Lungs News and Research

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Texas Heart Institute receives $4.1 million to determine the effect of pulseless blood flow on bodily functions

The National Institutes of Health (NIH) has awarded a $4.1 million grant to the Texas Heart Institute at St. Luke’s Episcopal Hospital (THI at SLEH) to determine the effect of pulseless blood flow on bodily functions. This knowledge will be used in the development of a total artificial heart (TAH) that produces continuous, pulseless blood flow.

18 Aug 2009

Disrupting the DNA-repair process

Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing themselves.

18 Aug 2009

Novel genome-analysis strategy to speed search for gene-disease links

University of Washington (UW) researchers have successfully developed a novel genome-analysis strategy for more rapid, lower cost discovery of possible gene-disease links. By saving time and lowering expenses, the approach makes it feasible for scientists to search for disease-causing genes in people with the same inherited disorder but without any family ties to each other.

18 Aug 2009

Genentech announces Phase III study results for Avastin (bevacizumab) in combination with chemo in HER2-negative breast cancer

Genentech, Inc. today announced that a Phase III study (RIBBON 2) of Avastin (bevacizumab) in combination with chemotherapy increased the time women with metastatic HER2-negative breast cancer whose initial chemotherapy had stopped working lived without the disease worsening (progression-free survival or PFS), compared to chemotherapy alone.

18 Aug 2009

Sleep apnea increases chances of dying

Nightly bouts of interrupted, oxygen-deprived sleep from a collapsed airway in the upper neck raises the chances of dying in middle-aged to elderly people by as much as 46 percent in the most severe cases, according to a landmark study on sleep apnea by lung experts at Johns Hopkins and six other U.S. medical centers.

18 Aug 2009

Keeping asthma under control

A new nationwide telephone survey of 1,001 asthma patients, conducted by AstraZeneca, found that while most patients with asthma understand the risks associated with uncontrolled asthma, they don't always act accordingly.

16 Aug 2009

Scientists create new method to detect genetic causes of complex diseases

Computational biologists at Carnegie Mellon University have developed an analytical technique to detect the multiple genetic variations that contribute to complex disease syndromes such as diabetes, asthma and cancer, which are characterized by multiple clinical and molecular traits.

14 Aug 2009

Researchers tackle aggressive cancer cells head on

A multi-institutional team of Boston-area researchers has discovered a chemical that works in mice to kill the rare but aggressive cells within breast cancers that have the ability to seed new tumors.

13 Aug 2009

Oncothyreon reports Q2 2009 financials

Oncothyreon Inc. (NASDAQ: ONTY) (TSX: ONY) today reported a net loss of $6.3 million, or $0.30 per basic and diluted share, for the three months ended June 30, 2009, compared with a net loss of $4.9 million, or $0.25 per basic and diluted share, for the comparable period in 2008.

12 Aug 2009

Tiotropium - corticosteroid combination improves lung disease survival

Sufferers of chronic obstructive pulmonary disease have a greater chance of survival when treated with a combination of drugs that includes tiotropium, according to research at the University of Illinois at Chicago.

12 Aug 2009

Assisted ventilation in cardiac arrest rescue may lower chances of survival

Arizona researchers have added another piece to the mounting body of evidence that suggests during resuscitation efforts to treat patients in cardiac arrest, "passive ventilation" significantly increases survival rates, compared to the widely practiced "assisted ventilation."

12 Aug 2009

Cannabis Science reports on future plans for cannabis drug trials

Cannabis Science, Inc. (OTCBB: CBIS) has announced that it has completed its review of the FDA licensing requirements and has made key progress with mapping out its initial cannabis drug medicines for FDA clinical trials.

12 Aug 2009

Outdoor air pollutants at high levels

Higher summertime levels of outdoor ground-level ozone, microscopic particle pollution like smoke and smog, as well as other air pollutants may cause anyone who is sensitive to these airborne contaminants to experience shortness of breath, wheezing and coughing, and may also trigger asthma attacks and cause lung irritation.

12 Aug 2009

Anti-psychotic drugs could help treat some major cancers

The observation that people taking medication for schizophrenia have lower cancer rates than other people has prompted new research revealing that anti-psychotic drugs could help treat some major cancers.

12 Aug 2009

Endocyte announces results from study of EC145 in patients with advanced non-small cell lung cancer

Results were presented at the 13th World Conference on Lung Cancer in San Francisco. The single arm Phase II study evaluated the therapeutic agent EC145 and the molecular imaging agent EC20 in 42 patients with advanced adenocarcinoma of the lung. Forty percent of patients involved in the clinical trial had already failed at least four chemotherapy regimens prior to enrollment in the study.

12 Aug 2009

New tool for virtual surgery simulates blood flow - helps plan child's delicate heart surgery

Researchers at the Georgia Institute of Technology, collaborating with pediatric cardiologists and surgeons at The Children's Hospital of Philadelphia, have developed a tool for virtual surgery that allows heart surgeons to view the predicted effects of different surgical approaches. By manipulating three-dimensional cardiac magnetic resonance images of a patient's specific anatomy, physicians can compare how alternative approaches affect blood flow and expected outcomes, and can select the best approach for each patient before entering the operating room.

12 Aug 2009

Aldose reductase inhibition shows promise for asthma

University of Texas Medical Branch at Galveston researchers have found that a single enzyme is apparently critical to most allergen-provoked asthma attacks - and that activity of the enzyme, known as aldose reductase, can be significantly reduced by compounds that have already undergone clinical trials as treatments for complications of diabetes.

11 Aug 2009

New type of anti-clotting drug called Apixaban

The dean of the University of Oklahoma College of Public Health and a team of scientists worldwide have found a better way to prevent deadly blood clots after joint replacement surgery - a major problem that results in thousands of unnecessary deaths each year. The research appears this week in the New England Journal of Medicine.

11 Aug 2009

New method for neonatal icus reduces infection and lung distress in preemies

A new method for improving quality of care can reduce hospital-acquired infections and chronic respiratory distress with oxygen dependency in premature infants in neonatal ICUs, according to a new study in CMAJ (Canadian Medical Association Journal).

11 Aug 2009

Researchers launch study into search-and-destroy antigen for deadly skin cancer

UT Southwestern Medical Center researchers are studying a new antigen to see whether it can track down and kill cancer cells in patients with recurring melanoma, the leading cause of skin cancer deaths.

11 Aug 2009