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Scientists unveil novel coronavirus variants in India

The global coronavirus disease COVID-19 pandemic is ravaging the world, affecting 185 countries and territories and infecting 2.4 million people. Now, a team of scientists aims to shed light on the variants of the novel coronavirus strains in India, showing how changes correspond to its transmission and how it causes disease.

19 Apr 2020

Research suggests Nelfinavir and Cepharanthine as potential anti-SARS-CoV-2 agents

A new study published in the journal bioRxiv in April 2020 reports the identification of a promising multidrug treatment against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for causing COVID-19 disease. The team predicts that this combination will prevent the virus from reproducing, hence both halting the transmission and progress of the disease.

19 Apr 2020

Scientists estimate fatality ratio across full spectrum of COVID-19 disease

A team of researchers from Imperial College London has conducted a study aimed at calculating a reasonably accurate case fatality ratio and infection fatality ratio, which is based on Chinese data as well as international reports. The research is published on the pre-print server MedRxiv.

19 Apr 2020

Hydroxychloroquine and azithromycin treatment in 80 COVID-19 patients: short-term outcomes

The COVID-19 pandemic is still spreading around the world and affecting nearly 2.4 million people, with over 164,000 dead so far. With neither vaccine nor proven therapeutic drug being available so far, the need of the hour is for effective treatment. Now, a new study reports the potential usefulness of a combination of hydroxychloroquine and azithromycin as a treatment in mild cases of COVID-19 infection and urges the need for further evaluation and widespread use if its findings are confirmed.

19 Apr 2020

West Virginia University creates aerosol-blocking intubation boxes to prevent COVID-19 spread

Boxes, barriers, and shields of various types and designs are making their appearance the world around to protect vulnerable healthcare professionals and allied staff from picking up COVID-19 while undertaking their duties. One such new device is the intubation box from West Virginia University (WVU).

19 Apr 2020

Computer simulations yield promising vaccine candidate against SARS-CoV-2

In a recent study that appeared on a preprint server bioRxiv, scientists from India designed a multi-epitope peptide-based vaccine that predicted high immunogenic response in the population.

19 Apr 2020

Salk scientists uncover surprising role of tuft cells in pancreatitis

Persistent inflammation of the pancreas (chronic pancreatitis) is a known risk factor for developing pancreatic cancer, the third-deadliest cancer in the United States.

18 Apr 2020

Researchers identify a promising model for testing COVID-19 therapeutics

After comparing how infections from SARS-CoV-2 (which causes COVID-19) and two other human coronaviruses develop in cynomolgus macaques, researchers report that SARS-CoV-2 gives the animals a mild COVID-19-like disease.

18 Apr 2020

McMaster researchers to study why some people are more susceptible to SARS-CoV-2

Two McMaster University professors have received research funding to boost their work to identify COVID-19 infection rates and to understand why some people are more susceptible to the virus.

17 Apr 2020

Study identifies two new viruses in Brazilian patients with suspected dengue

Two new species of viruses have been identified in blood samples taken from patients in Brazil's northern region who had similar symptoms to those of dengue or Zika, such as high fever, severe headache, rash and red skin spots.

17 Apr 2020

Greater occurrence of infections correlates with future cancer diagnosis

Patients experienced a greater occurrence of infections in the years preceding a cancer diagnosis.

17 Apr 2020

A promising antiviral drug to fight COVID-19 pandemic

COVID-19 patients in a clinical trial at Houston Methodist Hospital are responding quickly to the antiviral drug Remdesivir. The trial's criteria allows for the treatment of patients early in their clinical course and, in some cases, at times where they might have otherwise been intubated.

17 Apr 2020

Researchers develop COVID-19 guide for primary care health workers

Primary care health workers now have a guide for conducting remote consultation of suspected COVID-19 patients, developed by a team of researchers from Singapore and the UK.

17 Apr 2020

URMC launches new coronavirus study to examine immune response

The University of Rochester Medical Center is launching a new study to understand how the body's immune system responds to COVID-19, including if and when a person could be re-infected with the virus and whether some people have pre-existing immunity.

17 Apr 2020

Elderly patients underestimate the danger of pneumonia

Elderly patients who are hospitalised with pneumonia are twice as likely to die as those hospitalised with hip fractures.

17 Apr 2020

Scientists predict how the novel coronavirus spreads in a typical household

A team of scientists recently carried out a study on the transmissibility of the virus in households. Simply put, they’re trying to predict how the virus spreads in a typical family: if one person gets sick, how many others get sick? How sick? How long would it take the family to recover? These are the practical questions this study tries to answer.

17 Apr 2020

Gimsilumab trial starts in first US patient with ARDS and COVID-19

The first American patient with COVID-19 and acute respiratory distress syndrome (ARDS) has been put on the drug gimsilumab at Temple University Hospital, as part of the BREATHE clinical trial. The trial, sponsored by Roivant Sciences, will evaluate the effectiveness of intravenous gimsilumab in preventing death in patients with COVID-19 and ARDS.

16 Apr 2020

Random testing key to a safe exit from COVID-19 lockdown

The coronavirus disease (COVID019) global pandemic has placed many countries and regions in lockdown. There are thousands of cases reported daily, with the global infection toll topping 2.15 million. How can nations shift from lockdown back to normal daily routines while ensuring there won’t be a second wave of viral infection?

16 Apr 2020

On and off social distancing may be needed until 2022

Lockdown and social distancing measures are in place in many countries across the world, intended to stem the rapid spread of the coronavirus disease (COVID-19) global pandemic. These measures work by reducing the risk of viral transmission in communities, reducing the burden of the healthcare system in dealing with the surge of patients, overwhelming its resources and workforce. Now, experts warn that these social distancing measures may still be needed until 2022.

16 Apr 2020

Experts explain how to decontaminate N95 masks from SARS-CoV-2

Amid the coronavirus global pandemic, the world is facing a shortage of medical supplies, especially those intended to protect health workers. With the high demand for personal protective equipment (PPE), including surgical masks and N95 masks, many people are left with no choice but to try and decontaminate this equipment for extended use. Now, a new study by experts shows how N95 masks can be adequately decontaminated for further use.

16 Apr 2020