Blood Clot News and Research

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A Blood Clot is a mass of blood that forms when blood platelets, proteins, and cells stick together. When a blood clot is attached to the wall of a blood vessel, it is called a thrombus. When it moves through the bloodstream and blocks the flow of blood in another part of the body, it is called an embolus.

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Eli Lilly and Company and Bristol-Myers Squibb Company announced today that they have stopped enrollment in one of their two global Phase III studies evaluating necitumumab, an investigational anti-cancer agent, as a first-line treatment for advanced non-small cell lung cancer (NSCLC).

3 Feb 2011

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

People who follow a vegan lifestyle - strict vegetarians who try to eat no meat or animal products of any kind - may increase their risk of developing blood clots and atherosclerosis or "hardening of the arteries," which are conditions that can lead to heart attacks and stroke. That's the conclusion of a review of dozens of articles published on the biochemistry of vegetarianism during the past 30 years.

3 Feb 2011

Isis commences ISIS-FXIRx Phase 1 study for treatment of clotting disorders

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 1 study of ISIS-FXIRx, an antisense drug designed to treat clotting disorders. ISIS-FXIRx inhibits the production of Factor XI, a clotting factor that is an important component of the coagulation pathway. Because of its role in the intrinsic coagulation pathway, inhibition of Factor XI could offer an effective approach for preventing the formation of blood clots with a lower risk of bleeding.

2 Feb 2011

Scientist identifies natural signaling molecule that can prevent Hemophilia A

A scientist from The Scripps Research Institute has identified a new role for a natural signaling molecule in preventing blood clot formation. The molecule could become a target for the development of novel and cost-effective treatments for blood clotting diseases such as Hemophilia A.

1 Feb 2011

GATTEX Phase 3 pivotal study reaches primary efficacy endpoint of reducing PN in patients with SBS

NPS Pharmaceuticals, a specialty pharmaceutical company developing innovative therapeutics for rare gastrointestinal and endocrine disorders, today announced that its Phase 3 pivotal study of GATTEX met the primary efficacy endpoint of reducing parenteral nutrition dependence in patients with adult short bowel syndrome.

31 Jan 2011

Patients unaware of stroke risk with irregular heart beat conditions

Thousand of people who suffer from irregular heartbeats or conditions termed as arrhythmias are unaware they are at high risk of suffering a stroke. A new survey found that two of three people do not know the warning signs of shortness of breath and palpitations. Experts estimate that more than 4,000 strokes a year could be prevented by better awareness among the general public and doctors of the heart condition atrial fibrillation (AF) this manifests as palpitations and irregular heart beat.

31 Jan 2011

How estrogen decreases risk and delays onset and progression of Alzheimer's disease

An influential article in the journal Progress in Neurobiology provided one of the first comprehensive reviews of how estrogen potentially can protect against Alzheimer's disease and other neurological disorders.

27 Jan 2011

Microvisk secures £6 million to launch world's first diagnostic SmartStrip

Microvisk Technologies, the developer of a handheld system to monitor the blood clotting status of patients taking the drug Warfarin, has raised £6 million through a rights issue to existing investors in an oversubscribed round. This is the third successful funding round for Microvisk, which has secured £10.5m in the past 12 months - the largest amount raised by a UK life science company**.

26 Jan 2011

FDA approves On-X AAP with Vascutek Gelweave Valsalva Graft

On-X Life Technologies, announced today that it has received approval from the U.S. Food and Drug Administration to market the On-X Ascending Aortic Prosthesis with the Vascutek Gelweave Valsalva Graft.

23 Jan 2011

Pervasis to present PVS-10200 interim data from Phase 1/2 PAD clinical study at IC3D

Pervasis Therapeutics, Inc. today announced it will present interim data from the company's Phase 1/2 clinical study of PVS-10200, an investigational cell-based therapy under development to prevent restenosis in patients with peripheral arterial disease (PAD) who undergo an angioplasty and stent procedure in the superficial femoral artery.

21 Jan 2011

Ultrasound device shows promise in breaking up pulmonary embolisms: Research

A tiny ultrasound device that helps dissolve blood clots is showing promise in breaking up potentially deadly pulmonary embolisms, blockages of blood vessels in the lungs that can occur after long plane rides, surgery and extended bed rest.

20 Jan 2011

New research: HIV individuals are more likely to have stroke

New research suggests that people infected with human immunodeficiency virus may be up to three times more likely to have a stroke compared to those not affected with HIV. The study is published in the January 19, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Jan 2011

Boston Scientific announces merger agreement to acquire Atritech

Boston Scientific Corporation today announced the signing of a definitive merger agreement, under which the Company will acquire Atritech, a privately held company based in Plymouth, Minnesota.

19 Jan 2011

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

A complex sugar may someday become one of the most effective weapons to stop the spread of cholera, a disease that has claimed thousands of lives in Haiti since the devastating earthquake last year.

19 Jan 2011

MD Anderson experts create plan to guide women on healthy behaviors

"A woman's life changes at every decade and so does her body," says Therese Bevers, M.D., medical director of MD Anderson's Cancer Prevention Center. "And, just as a woman sets personal and work-related milestones, she also should set health goals for every stage of life."

19 Jan 2011

Study reports warfarin users may face risk of death after traumatic injuries

Warfarin use may be associated with a significant increase in the risk of death after traumatic injuries, according to a report posted online today that will appear in the May print issue of Archives of Surgery, one of the JAMA/Archives journals.

18 Jan 2011

Kaneka, Atrium Medical introduce FDA-approved Xpress-Way RX Extraction Catheter

Atrium Medical Corporation and Kaneka Corporation are proud to announce the introduction of the Xpress-Way RX Extraction Catheter. Xpress-Way RX has recently received FDA 510K clearance and is indicated for the removal of fresh, soft emboli and thrombi from vessels in the coronary and peripheral vasculature.

13 Jan 2011

Researchers launch estrogen therapy trial to study depression, cardiovascular illness in women

Researchers at the University of North Carolina at Chapel Hill have launched a new clinical trial to determine if estrogen replacement therapy may help prevent depression and cardiovascular illness in women between the ages of 45 and 55.

13 Jan 2011

Apixaban drug raises hope for DVT prevention in patients undergoing hip replacement surgery

A worldwide research consortium that includes the University of Oklahoma Health Sciences Center has proven that a new drug is more effective and easier to use than current medicines in the prevention of blood clots following hip replacement surgery.

12 Jan 2011

MSU researcher believes pregnancy unmasks predispositions to cardiovascular disease

As the rate of preterm delivery rises - accounting for 12.5 percent of all U.S. births - a Michigan State University epidemiologist is using a $3.7 million federal grant to uncover why some mothers who deliver babies early are at an increased risk of developing cardiovascular disease.

11 Jan 2011

Blood Clot News and Research

Further Reading

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Vegetarians, vegans need to increase omega-3 fatty acids and vitamin B12 to reduce heart disease risk

Isis commences ISIS-FXIRx Phase 1 study for treatment of clotting disorders

Scientist identifies natural signaling molecule that can prevent Hemophilia A

GATTEX Phase 3 pivotal study reaches primary efficacy endpoint of reducing PN in patients with SBS

Patients unaware of stroke risk with irregular heart beat conditions

How estrogen decreases risk and delays onset and progression of Alzheimer's disease

Microvisk secures £6 million to launch world's first diagnostic SmartStrip

FDA approves On-X AAP with Vascutek Gelweave Valsalva Graft

Pervasis to present PVS-10200 interim data from Phase 1/2 PAD clinical study at IC3D

Ultrasound device shows promise in breaking up pulmonary embolisms: Research

New research: HIV individuals are more likely to have stroke

Boston Scientific announces merger agreement to acquire Atritech

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

MD Anderson experts create plan to guide women on healthy behaviors

Study reports warfarin users may face risk of death after traumatic injuries

Kaneka, Atrium Medical introduce FDA-approved Xpress-Way RX Extraction Catheter

Researchers launch estrogen therapy trial to study depression, cardiovascular illness in women

Apixaban drug raises hope for DVT prevention in patients undergoing hip replacement surgery

MSU researcher believes pregnancy unmasks predispositions to cardiovascular disease

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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