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Low-dose aspirin enhances fecal occult blood test performance for detecting colorectal cancer

Use of low-dose aspirin prior to a newer type of fecal occult blood test is associated with a higher sensitivity for detecting advanced colorectal tumors, compared to no aspirin use, according to a study in the December 8 issue of JAMA.

8 Dec 2010

Expansion of newborn screening throws some families on a journey of great uncertainty

Mandatory genetic screening of newborns for rare diseases is creating unexpected upheaval for families whose infants test positive for risk factors but show no immediate signs of the diseases, a new UCLA study warns.

7 Dec 2010

Medication and blood transfusion reduce risk of recurrent strokes in young patients with sickle cell anemia

St. Jude Children's Research Hospital investigators discuss results of research into managing iron overload associated with stroke prevention in young sickle cell patients and the search for genetic predictors of stroke risk.

7 Dec 2010

Telik announces positive results from Phase 2 trial of ezatiostat in patients with MDS

Telik, Inc. today announced positive results from a Phase 2 multicenter trial of oral ezatiostat hydrochloride (TELINTRA, TLK199) in patients with an International Prognostic System Score of low to intermediate-1 risk myelodysplastic syndrome.

6 Dec 2010

Research highlighting treatment for pediatric SCD, malaria presented at ASH 2010

Red blood cells have the very important role of carrying oxygen from the lungs to the rest of the body; therefore, disorders that affect RBCs can have a significant impact on quality of life. Sickle cell disease and malaria are two common RBC diseases that affect a significant portion of the U.S. and global populations. Sickle cell disease, a genetic blood disorder that causes deformed and dysfunctional red blood cells, affects an estimated 70,000 to 100,000 Americans, while malaria affects approximately 1,500 Americans annually and 190 to 311 million people worldwide.

6 Dec 2010

Study compares efficacy of two treatments for iron overload caused by chronic transfusion therapy

Monthly blood transfusions combined with daily medication to remove the resulting excess iron remains the best approach for reducing the risk of recurrent strokes in young patients with sickle cell anemia, according to a preliminary analysis of a multicenter trial that includes St. Jude Children's Research Hospital.

6 Dec 2010

UIC scientist focuses on potential targets to inhibit malaria transmission

University of Illinois at Chicago researcher Dr. John Quigley will describe a promising new approach to blocking malaria transmission during the American Society of Hematology's annual meeting in Orlando, Fla.

6 Dec 2010

ASH to host annual meeting for blood disorders at Orange Convention Center

The American Society of Hematology (ASH) will host its 52nd annual meeting at the Orange County Convention Center in Orlando, FL, December 4-7. More than 20,000 attendees are expected for this event, which will highlight emerging research trends in the diagnosis, treatment, and understanding of blood disorders.

1 Dec 2010

Photoacoustic tomography and gold nanobeacons help researchers view blood vessel formation

See it for yourself: a new breakthrough in imaging technology using a combination of light and sound will allow health care providers to see microscopic details inside the body. Access to this level of detail potentially eliminates the need for some invasive biopsies, but it also has the potential to help health care providers make diagnoses earlier than ever before-even before symptoms arise. Details describing this advance are published online in the FASEB Journal (http://www.fasebj.org/content/early/2010/11/19/fj.10-171728.abstract).

23 Nov 2010

Racial and socioeconomic disparities exist in kidney transplantation

Research shows that people with low incomes are more likely to develop kidney failure and less likely to receive a living donor kidney transplant than people of other socioeconomic classes.

22 Nov 2010

Data from Rockwell Medical's Phase IIb study of SFP presented at ASN meeting

Rockwell Medical, a fully-integrated biopharmaceutical company offering innovative products and services targeting end-stage renal disease, chronic kidney disease, and iron deficiency anemia, announced today that the Company will present new data at the American Society of Nephrology meeting being held in Denver, Colorado, on its late-stage investigational drug Soluble Ferric Pyrophosphate, which is being studied for the treatment of iron-deficiency anemia in ESRD patients.

20 Nov 2010

FibroGen to present FG-4592 phase 2a study of patients with stage 3-4 Chronic Kidney Disease and anemia

FibroGen, Inc., today announced that new data from a phase 2a study of patients with stage 3-4 Chronic Kidney Disease and anemia will be presented demonstrating that its first-in-class, investigational oral anemia therapy FG-4592 works differently than erythropoiesis stimulating agents (ESAs) to increase hemoglobin.

19 Nov 2010

ENERCA network organizes European Symposium on rare anemias

It is estimated that rare diseases -those whose frequency is under 5 cases / 10,000 people- affect about 6% of the European population. In the field of anemia, 1% of couples are at risk of having a newborn with a severe syndrome of hemoglobin. More than 330,000 children are born worldwide each year affected by one of these diseases, being the most common disorders sickle cell anemia and thalassemia syndromes.

19 Nov 2010

DCR to present data on DaVita Cathaway program at ASN Annual Meeting

DaVita Clinical Research, a provider of clinical research and diagnostic laboratory services, announced today that 56 posters and five oral presentations will be presented by the Company's unsurpassed renal experts at the 43rd American Society of Nephrology (ASN) Annual Meeting and Scientific Exposition from November 16 - 21, 2010, at the Colorado Convention Center located in Denver, Colorado.

19 Nov 2010

BMEYE ccNexfin receives FDA clearance

BMEYE B.V., the innovators of combined totally noninvasive, beat-to-beat blood pressure and cardiac output monitoring announces FDA clearance and the United States launch of the BMEYE ccNexfin-the first totally noninvasive cardiovascular monitor with blood pressure, cardiac output, and Masimo rainbow SET Pulse CO-Oximetry measurements.

19 Nov 2010

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

Exelixis, Inc. today reported interim data from the cohort of patients with metastatic castration-resistant prostate cancer (CRPC) treated with XL184 in an ongoing phase 2 adaptive randomized discontinuation trial (RDT).

18 Nov 2010

Sangart's MP4CO receives orphan drug designation for acute pain in sickle cell disease

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen and other gas delivery, today announced that its investigational biopharmaceutical product, MP4CO, has been awarded orphan drug designation by the U.S. Food and Drug Administration (FDA) for use in treating acute painful sickling crises in patients with sickle cell disease.

15 Nov 2010

New mathematical model may help predict anemia risk

A collaboration between a physician-researcher at Massachusetts General Hospital (MGH) and a mathematician from Harvard University has led to development of a mathematical model reflecting how red blood cells change in size and hemoglobin content during their four-month lifespan.

15 Nov 2010

Incyte presents data on INCB28050 Phase IIa trial for rheumatoid arthritis at ACR/ARHP Meeting

Incyte Corporation announced the presentation of final six-month clinical data from the dose ranging, placebo-controlled Phase IIa trial of its orally available janus kinase (JAK) inhibitor INCB28050 in patients with active rheumatoid arthritis (RA).

11 Nov 2010

Researchers use near-infrared spectroscopy to study facial expressions in infants

Japanese research group led by Prof. Ryusuke Kakigi and Dr. Emi Nakato (National Institute for Physiological Sciences: NIPS) and Prof. Masami K Yamaguchi (Chuo University) found that the hemispheric differences in the temporal area overlying superior temporal sulcus (STS) when processing positive (happy) and negative (angry) facial expressions in infants.

9 Nov 2010

Hemoglobin News and Research

Low-dose aspirin enhances fecal occult blood test performance for detecting colorectal cancer

Expansion of newborn screening throws some families on a journey of great uncertainty

Medication and blood transfusion reduce risk of recurrent strokes in young patients with sickle cell anemia

Telik announces positive results from Phase 2 trial of ezatiostat in patients with MDS

Research highlighting treatment for pediatric SCD, malaria presented at ASH 2010

Study compares efficacy of two treatments for iron overload caused by chronic transfusion therapy

UIC scientist focuses on potential targets to inhibit malaria transmission

ASH to host annual meeting for blood disorders at Orange Convention Center

Photoacoustic tomography and gold nanobeacons help researchers view blood vessel formation

Racial and socioeconomic disparities exist in kidney transplantation

Data from Rockwell Medical's Phase IIb study of SFP presented at ASN meeting

FibroGen to present FG-4592 phase 2a study of patients with stage 3-4 Chronic Kidney Disease and anemia

ENERCA network organizes European Symposium on rare anemias

DCR to present data on DaVita Cathaway program at ASN Annual Meeting

BMEYE ccNexfin receives FDA clearance

Exelixis reports interim data of XL184 for metastatic castration-resistant prostate cancer

Sangart's MP4CO receives orphan drug designation for acute pain in sickle cell disease

New mathematical model may help predict anemia risk

Incyte presents data on INCB28050 Phase IIa trial for rheumatoid arthritis at ACR/ARHP Meeting

Researchers use near-infrared spectroscopy to study facial expressions in infants

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Expanding research and clinical options for children with cancer

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