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Full schedule of CoronaVac vaccine shown to be highly effective in children

A recent study on vaccine effectiveness showed that a complete primary immunization with CoronaVac effectively protects against severe coronavirus disease 2019 (COVID-19) for children and adolescents between 6 and 16 years of age – consistent with the results from phase 2 clinical trials. The paper is currently available on the Preprints with The Lancet* server while it undergoes peer review.

20 Feb 2022

Four times as many children hospitalized during Omicron COVID wave compared to Delta

The emergence of the SARS-CoV-2 Delta and Omicron variants caused severe disease and hospitalizations among children and adolescents.

20 Feb 2022

Trial of early antiviral therapy for COVID-19 shows no significant benefit

A new preprint research paper examines the efficacy of using three antivirals in various combinations in early infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

17 Feb 2022

Pediatric study links neighborhood-level factors to timely surgical care access

A new study from Ann & Robert H. Lurie Children's Hospital of Chicago found that children from less resourced neighborhoods were at increased odds of presenting with complicated appendicitis, an indicator of delayed access to surgical care.

16 Feb 2022

Study finds higher mortality rates among African children and adolescents hospitalized with COVID-19

African children and adolescents hospitalized with COVID-19 experience much higher mortality rates than Europeans or North Americans of the same age, according to a recently published study conducted by researchers from the Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) and the Institute of Human Virology Nigeria (IHVN).

16 Feb 2022

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

A new study evaluated the pregnancy outcomes of pregnant women in the third trimester who were infected by SARS-CoV-2 for the detection of the virus in the placenta and different samples of the newborn as well as detection of antibodies in the cord blood.

16 Feb 2022

Canadian study estimates incidence rate of reinfection in healthcare workers

Researchers from various Canadian institutions document all cases of reinfection discovered during the first year of the project.

15 Feb 2022

Cardiac MRI shows a similar injury pattern for vaccine-associated myocarditis

Vaccine-associated myocarditis shows a similar injury pattern on cardiac MRI compared to other causes of myocarditis, but abnormalities are less severe, according to a new study published in the journal Radiology.

15 Feb 2022

Estimates of COVID-19 hospitalization and ICU burden from existing severe acute respiratory infections surveillance

Researchers estimated SARS-CoV-2 hospitalization and ICU treatment during the first three waves of the COVID-19 pandemic.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

High mortality associated with acute kidney injury increases the urgency for new treatments

One in four patients who developed a serious complication called acute kidney injury (AKI) in the hospital will die within one year, heightening the urgency for new treatment options to improve patients' survival, according to a Henry Ford Health System study.

11 Feb 2022

The serious risks COVID-19 may pose during pregnancy

Researchers report on the potential for serious maternal illness or death during or following a pregnancy complicated by COVID-19.

9 Feb 2022

Study suggests people with COVID-19 exhibit increased risks and 12-month burdens of incident cardiovascular diseases

Researchers estimated the risk and one-year burden of a set of pre-specified cardiovascular outcomes in a cohort of COVID-19-infected patients who survived the acute phase of illness.

9 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Study explores SARS-CoV-2 manifestations and related hospitalizations in infants

A new study examined the clinical manifestations of SARS-CoV-2 infections, disease severity, and related hospitalization in infants in Canada.

8 Feb 2022

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

In a new study, a team of researchers assessed the differences in risk of hospitalization in adults after infection with SARS-CoV-2 Omicron and Delta variants.

8 Feb 2022

The impact of SARS-CoV-2 variants on clinical trajectory and outcome

The current study describes the results of examining a patient database to understand just how Omicron affected the clinical outcome.

8 Feb 2022

Impact of SARS-CoV-2 infection in pregnant women on maternal and perinatal outcomes

Researchers conducted a retrospective cohort analysis by reviewing medical records of pregnant women to examine the impact of SARS-CoV-2 maternal infection on maternal and perinatal outcomes.

8 Feb 2022

$Spinal anesthesia not superior to general anesthesia for hip-fracture surgery in older adults$

Spinal anesthesia not superior to general anesthesia for hip-fracture surgery in older adults

Spinal anesthesia is not safer or more effective than general anesthesia in patients who undergo surgery for hip fractures, according to a major study.

7 Feb 2022

Investigating the immunology of COVID-19 infected children

Researchers published a new study that focused on the key principles of developmental immunology associated with immunobiology and the clinical impacts of COVID-19 infections in children and adults.

7 Feb 2022

Intensive Care News and Research

Full schedule of CoronaVac vaccine shown to be highly effective in children

Four times as many children hospitalized during Omicron COVID wave compared to Delta

Trial of early antiviral therapy for COVID-19 shows no significant benefit

Pediatric study links neighborhood-level factors to timely surgical care access

Study finds higher mortality rates among African children and adolescents hospitalized with COVID-19

Pregnancy outcomes of pregnant women infected by SARS-CoV-2

Canadian study estimates incidence rate of reinfection in healthcare workers

Cardiac MRI shows a similar injury pattern for vaccine-associated myocarditis

Estimates of COVID-19 hospitalization and ICU burden from existing severe acute respiratory infections surveillance

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

High mortality associated with acute kidney injury increases the urgency for new treatments

The serious risks COVID-19 may pose during pregnancy

Study suggests people with COVID-19 exhibit increased risks and 12-month burdens of incident cardiovascular diseases

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Study explores SARS-CoV-2 manifestations and related hospitalizations in infants

Impact of SARS-CoV-2 Omicron and Delta variants on serious hospital events

The impact of SARS-CoV-2 variants on clinical trajectory and outcome

Impact of SARS-CoV-2 infection in pregnant women on maternal and perinatal outcomes

Spinal anesthesia not superior to general anesthesia for hip-fracture surgery in older adults

Investigating the immunology of COVID-19 infected children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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