Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

7 Feb 2022

Study looks at rapid antigen vs. PCR tests in the emergency department triage

In a recent study posted to the Lancet preprint* server, researchers assessed the utility of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) rapid antigen testing (RAT) for patient triage in the hospital emergency department (ED).

7 Feb 2022

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

A recent study posted to the Research Square* preprint server and under consideration for inclusion in the journal Scientific Reports assessed the epidemiology of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) reinfections.

6 Feb 2022

First case of avian influenza A(H5N1) in asymptomatic flock owner in Europe

Following an outbreak of highly pathogenic avian influenza A(H5N1) in a flock of around 125 Muscovy ducks in a domestic setting in South West England on 22 December 2021, the virus was later also confirmed in the asymptomatic flock owner.

6 Feb 2022

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

The first published case describing the Delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a domestic cat in the United States highlights the realistic scenario of spillover infections with emerging viral variants that threaten human and animal health.

6 Feb 2022

Greater neutralizing titers observed in vaccinated individuals with breakthrough Omicron infection

Researchers assess the neutralizing power of plasma samples collected from Omicron convalescent individuals who were either vaccinated or unvaccinated.

6 Feb 2022

Many COVID-19 patients still contagious after five days

A new study shows that a high proportion of individuals still test positive for SARS-CoV-2 infection using RATs after five days of quarantine.

6 Feb 2022

Exploring the comparative efficacy of booster vaccines against SARS-CoV-2 Omicron and Delta variants

In a new study, researchers assessed the effectiveness of SARS-CoV-2 Omicron and Delta variants.

4 Feb 2022

Investigation of SARS-CoV-2 outbreak in UK office highlights the need for a site-specific COVID-19 prevention strategy

In a new study, researchers comprehensively investigated a public-facing office in England where a SARS-CoV-2 outbreak occurred during August-September 2021 to identify workplace and worker-related risk factors.

4 Feb 2022

Researchers suggest that visible blue light is a safe and variant-agnostic therapy against SARS-CoV-2

In a new study, researchers showed that 425 nm blue light can inactivate all major SARS CoV 2 variants.

4 Feb 2022

Study shows SARS-CoV-2 infection can change nasopharyngeal microbiota composition in pregnancy

A recent study from Spain showed that the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can change the overall structure and diversity of the nasopharyngeal microbiota in pregnant women – which persists even weeks after clinical infection. The paper is currently available on Research Square preprint* server.

3 Feb 2022

Understanding public responses to UK's COVID test, trace and isolate measures

Researchers investigate the public behaviors in response to the United Kingdom test, trace, and isolate (TTI) policy in July 2021.

3 Feb 2022

SARS-CoV-2 human challenge study offers novel insights into viral kinetics

Researchers discuss the results of a human challenge study to provide novel insights into the early dynamics of SARS-CoV-2 infection.

3 Feb 2022

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

In a new study, researchers explored the systemic immune responses during the acute and convalescent phases of SARS-CoV-2 in children and adults with the same disease severity.

3 Feb 2022

Studying the efficacy of a SARS-CoV-2 vaccine booster dose

In a new study, a team of researchers assessed the efficacy of booster doses of Ad26.COV2.S (Jansen) SARS-CoV-2 vaccine.

3 Feb 2022

Protocol for a systematic review to evaluate the role of viral cultures for assessing airborne transmission of SARS-CoV-2

Researchers presented the protocol for a systematic review assessing viral cultures for airborne transmission of SARS-CoV-2.

3 Feb 2022

Polymerase Chain Reaction News and Research

Further Reading

USP22 crucial for type III interferon signaling and SARS-CoV-2 infection

Study looks at rapid antigen vs. PCR tests in the emergency department triage

Vaccine-induced immunity and prior infection effective in reducing COVID severity in reinfections

First case of avian influenza A(H5N1) in asymptomatic flock owner in Europe

Detection of SARS-CoV-2 Delta variant infection in a domestic cat

Greater neutralizing titers observed in vaccinated individuals with breakthrough Omicron infection

Many COVID-19 patients still contagious after five days

Exploring the comparative efficacy of booster vaccines against SARS-CoV-2 Omicron and Delta variants

Investigation of SARS-CoV-2 outbreak in UK office highlights the need for a site-specific COVID-19 prevention strategy

Researchers suggest that visible blue light is a safe and variant-agnostic therapy against SARS-CoV-2

Study shows SARS-CoV-2 infection can change nasopharyngeal microbiota composition in pregnancy

Understanding public responses to UK's COVID test, trace and isolate measures

SARS-CoV-2 human challenge study offers novel insights into viral kinetics

Innate and adaptive immune responses to SARS-CoV-2 in convalescent children and adults

Studying the efficacy of a SARS-CoV-2 vaccine booster dose

Protocol for a systematic review to evaluate the role of viral cultures for assessing airborne transmission of SARS-CoV-2

Evaluating vaccine effectiveness and determining differences across demographic and clinical risk factors of COVID-19

Analysis of SARS-CoV-2 Omicron variant-associated travel restrictions worldwide

Exploring protection via a 4th dose of BNT162b2 against SARS-CoV-2 Omicron variant in Israel

Rapid antigen test for SARS-CoV-2 shows lower sensitivity

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