Precision Medicine News and Research

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Pitt researchers to contribute to building an atlas of cellular senescence

Most cells throughout the body can divide and multiply to replace old cells and repair damaged tissue, but in response to certain stresses, cells can lose their ability to proliferate. These so-called senescent cells accumulate with age and may contribute to cancer and age-related disorders, such as chronic lung disease, cardiovascular disease, frailty and dementia, by pumping out signals that damage neighboring tissues.

21 Oct 2021

New ESMO Clinical Practice Guideline for managing metastatic breast cancer released

The much-anticipated ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer has been published today in Annals of Oncology.

19 Oct 2021

High levels of cancer-fighting immune cells could indicate a better chance of survival

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment.

18 Oct 2021

Scientists identify gene responsible for food-dependent form of Cushing's Syndrome

A team of scientists in Montreal and Paris has succeeded in identifying the gene responsible for the development of a food-dependent form of Cushing's Syndrome, a rare disease affecting both adrenal glands.

15 Oct 2021

Qatar genomics study reveals key historical and social insights into Arab populations

Researchers in Qatar have unveiled a high-resolution map of the genetic structure of Arab and Middle Eastern populations, providing new insights into human history in the region and ancestral patterns that may help to explain local human traits and disease risks.

15 Oct 2021

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

13 Oct 2021

CAST brings advancements in genomic medicine to admixed individuals

One way to make health care more personalized is to use a person's DNA sequence — or genome — to predict their risk of disease. But as the field of precision medicine grows, so have concerns that we may be leaving a large fraction of Americans out.

12 Oct 2021

New federated analytics system can act as a game-changer towards personalized medicine

Predictive, preventive, personalized and participatory medicine, known as P4, is the healthcare of the future. To both accelerate its adoption and maximize its potential, clinical data on large numbers of individuals must be efficiently shared between all stakeholders.

11 Oct 2021

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

11 Oct 2021

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

A recently released paper from the Department of Physiology and Sanders-Brown Center on Aging (SBCoA) at the University of Kentucky College of Medicine suggests that your genetics can influence your response to Alzheimer's disease pathology.

8 Oct 2021

New Maternal and Child Health Research Institute launched to improve national health in Singapore

The SingHealth Duke-NUS Maternal and Child Health Research Institute was launched at KK Women's and Children's Hospital (KKH) today by Masagos Zulkifli, Singapore's Minister for Social and Family Development and Second Minister for Health.

8 Oct 2021

Deadly subtype of T-cell lymphoma harbors unique mutations

An especially deadly subtype of T-cell lymphoma is distinguished by unique mutations in a specific protein signaling pathway, according to a study published in the journal Blood.

7 Oct 2021

Collins’ skillful piloting helped NIH steer clear of political minefields

It's remarkable that the reputation of the National Institutes of Health has remained mostly intact through the covid-19 pandemic, even as other federal science agencies, including the Food and Drug Administration and Centers for Disease Control and Prevention, have come under partisan fire.

6 Oct 2021

UD chemical engineer aims to improve the delivery of therapeutic medicines to the body

The human body has built-in protections to keep pathogens out. That sneezing fit or stuffy nose when you have a cold? That's your body leveraging mucosal linings in your respiratory system to expel the offending virus.

5 Oct 2021

Novel mouse model uncovers resistance mechanism in human breast cancers

Scientists at the Medical College of Wisconsin Cancer Center and an international team of collaborators have generated mice with an improved hormone profile that supports growth and metastatic spread of implanted human breast tumors.

5 Oct 2021

On-demand brain stimulation alleviates severe depression

The study, which appears in the Oct. 4, 2021, issue of Nature Medicine, represents a landmark success in the years-long effort to apply advances in neuroscience to the treatment of psychiatric disorders.

4 Oct 2021

Additional supportive care services benefit older adults receiving chemotherapy, study finds

A clinical trial led by researchers at City of Hope, a world-renowned cancer research and treatment organization, showed that patients over 65 receiving chemotherapy experienced significantly fewer treatment-related side effects when a multidisciplinary team of experts analyzed each case and introduced personalized interventions.

30 Sep 2021

Research points the way to identifying new precision treatments for cancer

Researchers at University of California San Diego and University of California San Francisco have mapped out how hundreds of mutations involved in two types of cancer affect the activity of discrete groups of proteins that are the ultimate actors behind the disease.

30 Sep 2021

New drug combination effectively suppresses SARS-CoV-2 infection

More countries with greater resources are opening up for a more normal life. But COVID-19 and the SARS-CoV-2 virus are still a significant threat in large parts of the world.

30 Sep 2021

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

The University of Texas MD Anderson Cancer Center and BostonGene Corporation today announced a strategic alliance to advance the development and clinical integration of multiplatform biomarker signatures.

28 Sep 2021

Precision Medicine News and Research

Pitt researchers to contribute to building an atlas of cellular senescence

New ESMO Clinical Practice Guideline for managing metastatic breast cancer released

High levels of cancer-fighting immune cells could indicate a better chance of survival

Scientists identify gene responsible for food-dependent form of Cushing's Syndrome

Qatar genomics study reveals key historical and social insights into Arab populations

Study shows how tissue-derived T cells can damage other organs in stem cell transplant patients

CAST brings advancements in genomic medicine to admixed individuals

New federated analytics system can act as a game-changer towards personalized medicine

Common oral diuretic pill may be a potential candidate for Alzheimer's treatment

Genetics can influence a person's response to Alzheimer's disease pathology, research suggests

New Maternal and Child Health Research Institute launched to improve national health in Singapore

Deadly subtype of T-cell lymphoma harbors unique mutations

Collins’ skillful piloting helped NIH steer clear of political minefields

UD chemical engineer aims to improve the delivery of therapeutic medicines to the body

Novel mouse model uncovers resistance mechanism in human breast cancers

On-demand brain stimulation alleviates severe depression

Additional supportive care services benefit older adults receiving chemotherapy, study finds

Research points the way to identifying new precision treatments for cancer

New drug combination effectively suppresses SARS-CoV-2 infection

BostonGene and MD Anderson collaborate to advance the development of multiplatform biomarker signatures

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