Protein C News and Research

RSS

Interval between doses of Oxford COVID-19 vaccine can be safely extended to 3 months, suggests study

A 3-month interval between doses of the Oxford COVID-19 vaccine results in higher vaccine efficacy than a 6-week interval, with the first dose offering 76% protection in the 3 months between doses.

20 Feb 2021

Antimicrobial resistance to critical drugs spirals in low- and middle-income countries

As antibiotic use grows in lower-income countries so does antibiotic resistance, says report.

20 Feb 2021

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

20 Feb 2021

Study: Longevity gene protects brain stem cells from the harmful effects of stress

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators.

20 Feb 2021

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Scientists have discovered the first evidence of protein folding driven by liquid-liquid phase separation, a phenomenon in which fluids form into microscopic droplets and separate inside cells -- like drops of oil in water.

20 Feb 2021

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

A new study reports the development of nanoantibodies (nAbs) – also called or nanobodiesTM or single-domain antibodies – that effectively bind the SARS-CoV-2 spike protein from the ancestral Wuhan variant as well as the recently detected UK and South African variants.

19 Feb 2021

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

Researchers report on a Chicken-derived antibody against SARS-CoV-2, offering preliminary data on a potential therapeutic for COVID-19 warranting further research.

19 Feb 2021

COVID-19 and lung cancer have a common pathway, say researchers

A new preprint on the bioRxiv* server describes the common features COVID-19 shares with lung cancer.

19 Feb 2021

Juvenile inflammatory rheumatic disease associated with higher antibody responses to seasonal coronaviruses

A new study released on the bioRxiv* server compared the antibodies produced in young patients with these three conditions against the two immunodominant coronavirus antigens, the spike and the nucleocapsid antigens.

19 Feb 2021

Scientists use computer simulations to identify future targets for treatment of Covid-19

University of Warwick scientists model movements of nearly 300 protein structures in Covid-19. Scientists can use the simulations to identify potential targets to test with existing drugs, and even check effectiveness with future Covid variants.

19 Feb 2021

Domestic dogs unlikely to transmit SARS-CoV-2, say researchers

Researchers in Spain and Germany have conducted a study showing that domestic dogs are unlikely to contribute to the transmission and community spread of SARS-CoV-2 – the agent that causes COVID-19.

19 Feb 2021

Developing Biochemically Sensitive Membranes with Electrochemistry

In this interview, News-Medical Life Sciences talks to Lane Baker, Professor of Chemistry at Indiana University Bloomington about the role of electrochemistry in developing biochemically sensitive membranes as well the work ongoing at the Baker lab.

From Pittcon 19 Feb 2021

How does the SARS-CoV-2 E484K mutation increase viral fitness?

How do mutations benefit SARS-CoV-2? To explore this, a team of researchers from China took a closer look at the physical interactions that occur between the proteins after viral mutation.

19 Feb 2021

Molecular modeling helps identify the binding site of antidepressantss

The effects of selective serotonin reuptake inhibitors (SSRIs) and other conventional antidepressants are believed to be based on their increasing the levels of serotonin and noradrenalin in synapses, while ketamine, a new rapid-acting antidepressant, is thought to function by inhibiting receptors for the neurotransmitter glutamate.

19 Feb 2021

Trispecific antibody targets cancer cells, natural killer cells

Several treatments for cancer have been devised by science, but unfortunately none of them are completely efficient or foolproof.

19 Feb 2021

Inhibitors to target SARS-CoV-2 viral protein display strong antiviral activity in transgenic mouse model

Inhibitors based on approved drugs and designed to disrupt the SARS-CoV-2 viral protein Mpro display strong antiviral activity both in vitro and in a transgenic mouse model, a new study reports.

18 Feb 2021

Immune response to SARS-CoV-2 may be limited by a set of genes

Neutralizing antibodies develop within two weeks of a SARS-CoV-2 infection, but their durability and intensity can vary by individual, prompting concerns about the prospects of long-lasting immunity and efficacy of COVID-19 vaccines.

18 Feb 2021

Novel gel electrophoresis method for MS-based quantification of protein biomarkers

Mass spectrometry (MS) is a powerful method for biomarker analysis because it enables highly sensitive and accurate measurement of target molecules in clinical samples.

18 Feb 2021

O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines

The mapping of O-glycosites requires instruments that can support electron transfer dissociation (ETD) fragmentation. In a new study published on the bioRxiv preprint server, researchers report their results on whether O-glycosylation patterns affect immunogens for vaccine development.

18 Feb 2021

Could measles virus vectors be used for a new COVID-19 vaccine?

A research team at the Institut Pasteur in France describes the successful development of such a vaccine utilizing a measles virus vector.

18 Feb 2021

Protein C News and Research

Interval between doses of Oxford COVID-19 vaccine can be safely extended to 3 months, suggests study

Antimicrobial resistance to critical drugs spirals in low- and middle-income countries

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

Study: Longevity gene protects brain stem cells from the harmful effects of stress

Researchers discover first evidence of protein folding driven by liquid-liquid phase separation

Llama-derived nanobodies show neutralizing activity against SARS-CoV-2 variants of concern in vitro

Chicken-derived antibody shows potent neutralizing capacity against SARS-CoV-2 in vitro

COVID-19 and lung cancer have a common pathway, say researchers

Juvenile inflammatory rheumatic disease associated with higher antibody responses to seasonal coronaviruses

Scientists use computer simulations to identify future targets for treatment of Covid-19

Domestic dogs unlikely to transmit SARS-CoV-2, say researchers

Developing Biochemically Sensitive Membranes with Electrochemistry

How does the SARS-CoV-2 E484K mutation increase viral fitness?

Molecular modeling helps identify the binding site of antidepressantss

Trispecific antibody targets cancer cells, natural killer cells

Inhibitors to target SARS-CoV-2 viral protein display strong antiviral activity in transgenic mouse model

Immune response to SARS-CoV-2 may be limited by a set of genes

Novel gel electrophoresis method for MS-based quantification of protein biomarkers

O-glycosylation of SARS-CoV-2 spike protein in insect and human cell lines

Could measles virus vectors be used for a new COVID-19 vaccine?

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News