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Investigational drug may hold benefit for patients with lung and ovarian cancers

In a first-time disclosure of IPN60090, a small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), researchers from The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Ipsen Biopharmaceuticals reported the preclinical discovery and early-stage clinical development of this novel drug. IPN60090, now under investigation in a Phase I trial, may hold benefit for certain patients with lung and ovarian cancers.

27 Apr 2020

Artificial intelligence: A backup and excellent benefit for radiologists

Diagnosing emphysema and classifying its severity have long been more art than science.

27 Apr 2020

Study: Combination of melanoma drugs prevents cancer from growing or spreading

A first-of-its-kind randomized clinical trial offers strong and perhaps surprising evidence that a combination of two targeted melanoma drugs when given continuously keeps patients' cancer from growing or spreading longer when compared with intermittent treatment, according to study results to be presented at the 2020 virtual annual meeting of the American Association for Cancer Research.

27 Apr 2020

Talazoparib did not show overall survival benefit in patients with advanced BRCA-mutated breast cancer

New data from the Phase III EMBRACA trial led by researchers at The University of Texas MD Anderson Cancer Center found the PARP inhibitor talazoparib did not demonstrate a statistically significant overall survival (OS) benefit for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

27 Apr 2020

Researchers are closer to developing fast, flexible, and powerful bioelectronic devices

Dion Khodagholy, assistant professor of electrical engineering, is focused on developing bioelectronic devices that are not only fast, sensitive, biocompatible, soft, and flexible, but also have long-term stability in physiological environments such as the human body.

27 Apr 2020

Early Heparin therapy improves hypoxia in COVID-19 patients

The systemic use of heparin for treating severe coronavirus disease (COVID-19) showed significant improvements in oxygen exchange and overall clinical presentation of patients, as reported by a study from Brazil available on a preprint server medRxiv.

26 Apr 2020

UCLA scientists receive awards to pursue treatments and vaccines for COVID-19

Three researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards to pursue treatments and vaccines for COVID-19 from the California Institute for Regenerative Medicine, the state's stem cell agency.

25 Apr 2020

New study indicates novel therapies for Duchenne muscular dystrophy

When an actor is unable to perform in the theatre, an understudy--ideally one with some practice in the role--can take her place on stage.

25 Apr 2020

CBT found to be effective in treating binge eating disorders in adolescents

A study published in Psychotherapy and Psychosomatics found cognitive behavioral therapy to be effective, in treating binge eating disorder in adolescence, with lasting results.

24 Apr 2020

FAU scientists aim to develop a passive vaccine against COVID-19

Nothing less than the development of a passive vaccine against Covid-19 has been undertaken by a team of scientists from Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinkum Erlangen and their partners from the Fraunhofer Institute for Cell Therapy and Immunology in Leipzig and the German Primate Centre in Göttingen.

24 Apr 2020

Global healthy living foundation launches autoimmune patient COVID-19 research project

Today the Global Healthy Living Foundation (GHLF) and CreakyJoints®, its digital patient community for people with all forms of arthritis, announced the launch of the Autoimmune COVID-19 Project.

24 Apr 2020

Therapeutic antibody successfully prevents metastases in mice with breast or lung cancer

A receptor in the cell layer that lines the blood vessels from the inside stimulates both the formation of new blood vessels in tumors and metastasis.

24 Apr 2020

Biosero and Scripps Research Institute offer automated lab screening for COVID-19 drug therapy candidates

Biosero has designed and implemented an automated lab workflow for Scripps Research Institute so researchers can accelerate the screening of COVID-19 drug therapy candidates.

24 Apr 2020

Scientists are developing synthetic COVID-19 antibody to treat sick patients

A team of researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with GenScript, is developing a synthetic antibody to SARS-CoV-2, the virus that causes coronavirus disease (COVID-19). This antibody is intended to block the virus from entering human lung cells, and would be another potential treatment option for COVID-19.

24 Apr 2020

Novela Neurotech joins INCF's Industry Advisory Council to help guide efforts in neuroscience

Novela Neurotech, a medtech company at the forefront of accelerating novel neurological therapies through neural data curation, collaboration and sharing, is excited to join INCF's Industry Advisory Council to help guide efforts at industry and academic collaborations in the neuroscience, data science and neurotech sphere.

24 Apr 2020

Australian researchers develop world’s first ultrasound biosensor

Australian researchers have made a world-first breakthrough that has the potential to monitor the changes in pH levels and other responses to therapy in stroke and cancer patients.

24 Apr 2020

Combination therapy boosts the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

Research looks at best ways to tackle coronavirus crisis

A new study published in the journal Frontiers in Microbiology in April 2020 discusses the most attractive approaches among the broad spectrum of experimental and theoretical strategies being worked on to counter the COVID-19 pandemic.

24 Apr 2020

Graphene-based nanomedicine enables targeted cancer treatment at molecular level

"Three" kinds of regalia such as crown, orb, and sward are often necessary to be a high king for conquering the world. For fighting off cancerous diseases, what do we need? This "triple" chemical modified nanomaterial might be save the patient.

23 Apr 2020

New report highlights blood clot dangers in patients with COVID-19

A special report published today in the journal Radiology outlines prevention, diagnosis and treatment of complications stemming from blood clots in patients with COVID-19. The journal also published two research letters and a case study on this topic.

23 Apr 2020

Therapy News and Research

Investigational drug may hold benefit for patients with lung and ovarian cancers

Artificial intelligence: A backup and excellent benefit for radiologists

Study: Combination of melanoma drugs prevents cancer from growing or spreading

Talazoparib did not show overall survival benefit in patients with advanced BRCA-mutated breast cancer

Researchers are closer to developing fast, flexible, and powerful bioelectronic devices

Early Heparin therapy improves hypoxia in COVID-19 patients

UCLA scientists receive awards to pursue treatments and vaccines for COVID-19

New study indicates novel therapies for Duchenne muscular dystrophy

CBT found to be effective in treating binge eating disorders in adolescents

FAU scientists aim to develop a passive vaccine against COVID-19

Global healthy living foundation launches autoimmune patient COVID-19 research project

Therapeutic antibody successfully prevents metastases in mice with breast or lung cancer

Biosero and Scripps Research Institute offer automated lab screening for COVID-19 drug therapy candidates

Scientists are developing synthetic COVID-19 antibody to treat sick patients

Novela Neurotech joins INCF's Industry Advisory Council to help guide efforts in neuroscience

Australian researchers develop world’s first ultrasound biosensor

Combination therapy boosts the immune system's appetite for cancer

Research looks at best ways to tackle coronavirus crisis

Graphene-based nanomedicine enables targeted cancer treatment at molecular level

New report highlights blood clot dangers in patients with COVID-19

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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