Infectious Diseases News and Research

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Thailand threatens big pharma companies

Thailand's minister for health has reportedly threatened to override international patents on even more drugs if the big pharmaceutical manufacturers do not significantly cut their prices.

19 Feb 2007

Scientists discover vulnerable area on HIV that could lead to development of HIV/AIDS vaccine

Scientists on Wednesday announced they had identified a vulnerable area on HIV that might be susceptible to antibodies and could prevent the virus from infecting human cells, Reuters Health reports. The findings are published in the Feb. 15 issue of the journal Nature.

19 Feb 2007

Mathematical model predicts cholera outbreaks

In research done over the past seven years, Pascual and colleagues have found evidence that a phenomenon known as the El Nino-Southern Oscillation (ENSO), a major source of climate variability from year to year, influences cycles of cholera in Bangladesh.

18 Feb 2007

Study shows PanK2 enzyme within mitochondria is triggered by the first step in fatty acid breakdown

Just as homes have smoke detectors, cells have an enzyme that responds to a buildup of fatty acids by triggering the production of a key molecule in the biochemical pathway that breaks them down, according to investigators at St. Jude Children's Research Hospital. This provides the cell energy while reducing the chance that excess fatty acids will accumulate.

15 Feb 2007

Maraviroc to receive accelerated review in U.S. and Europe

Pfizer announced today that marketing authorization applications for maraviroc will receive accelerated review in both the United States and Europe. Accelerated reviews are granted to potential medicines that, if approved, would represent significant improvements over current therapies.

13 Feb 2007

Seasonal flu vaccine offers some protection from H5N1

The yearly influenza vaccine that health officials urge people to get each fall might also offer certain individuals some cross protection against the H5N1 virus commonly known as bird flu, according to investigators at St. Jude Children's Research Hospital.

13 Feb 2007

New patented technology for next generation of DNA and RNA microarrays

A novel invention developed by a scientist from New York Institute of Technology (NYIT) could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer's, diabetes, and genetic and infectious diseases.

13 Feb 2007

South Africa starts major HIV/AIDS vaccine trial

The launch of the first large-scale study to evaluate a candidate HIV vaccine on the African continent was announced today by study collaborators in the United States and South Africa. The trial will involve up to 3,000 participants at five sites throughout South Africa and is expected to continue for four years.

11 Feb 2007

Scientists find connection between nerve cells and immune system

A direct connection exists between the brain and the immune system – at least in mice. Scientists at the Helmholtz Centre for Infection Research in Braunschweig conducted a comprehensive study of mice intestine and the surrounding blood and lymph vessels using special microscopy and marking techniques.

11 Feb 2007

Fighting influenza with 40,000 blood samples

Four million people die every year from respiratory diseases such as viral influenza. For elderly people in particular, an infection can be dangerous. What is more, the flu vaccine is not as effective with this risk group as it is with younger people.

7 Feb 2007

Different treatments may be needed for chronic asthma, depending on whether it results from allergies or lung infections

Researchers have now identified a particular gene that influences how severe a M. pneumoniae infection may be, which in turn suggests that a different strategy might be needed for treating asthma resulting from this and similar lung infections rather than allergies.

31 Jan 2007

Merck lobbying States to mandate Gardasil for school girls

Merck recently has been providing lobbyists throughout the country with information about its human papillomavirus vaccine Gardasil in an effort to encourage states to mandate that middle-school age girls receive it, the Baltimore Sun reports.

30 Jan 2007

Startling results from first study of HIV dementia on the Africa

An international study led by Johns Hopkins suggests that the rate of HIV-associated dementia is so high in sub-Saharan Africa that HIV dementia along with Alzheimer's disease and dementia from strokes may be among the most common forms of dementia in the world.

30 Jan 2007

Number of Parkinson's sufferers will double in next 25 years

The study highlights the significant challenge facing countries with rapidly growing economies, particularly in Asia, many of which are ill prepared to meet this impending public health threat.

29 Jan 2007

Public standards for world medications to treat neglected infectious diseases

The United States Pharmacopeia (USP) has released free documentary standards for medicines used outside the United States to treat neglected infectious diseases.

29 Jan 2007

A plasminogen-activating protease specifically controls the development of primary pneumonic plague

The deadly attack of the bacterium that causes pneumonic plague is significantly slowed when it can't make use of a key protein, scientists at Washington University School of Medicine in St. Louis report in Science.

28 Jan 2007

Antiretroviral resistance testing in HIV infected patients improves health and saves costs

In a newly published study Swiss researchers document that antiretroviral resistance testing in HIV infected patients with treatment failure not only leads to better health but also saves costs to society.

25 Jan 2007

AstraZeneca makes $100 million investment in Boston

AstraZeneca has announced a $100 million research investment to strategically boost work in the infectious disease area and continue its incremental growth in cancer research at its research center near Boston, Massachusetts.

22 Jan 2007

Sequella receives FDA fast track status for pulmonary tuberculosis drug

Sequella, Inc. has announced it has received Fast Track designation from the U.S. Food and Drug Administration (FDA) for SQ109, the company's proprietary lead drug candidate for treatment of pulmonary tuberculosis (TB).

22 Jan 2007

More aid required for chronic conditions in developed world

In an article published in the January 18, 2007, issue of the New England Journal of Medicine, Gerard Anderson, PhD, professor in the Department of Health Policy and Management at the Johns Hopkins Bloomberg School of Public Health, highlights the need for more international assistance to address chronic non-communicable conditions affecting people living in low and middle income countries.

18 Jan 2007