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New findings reveal long-term influences of infant formula composition

New findings from the Monell Center reveal that weight gain of formula-fed infants is influenced by the type of formula the infant is consuming. The findings have implications related to the infant's risk for the development of obesity, diabetes and other diseases later in life.

27 Dec 2010

Researchers develop microfluidic device to orient hundreds of embryos for research

Researchers have developed a microfluidic device that automatically orients hundreds of fruit fly and other embryos to prepare them for research. The device could facilitate the study of such issues as how organisms develop their complex structures from single cells -- one of the most fascinating aspects of biology.

27 Dec 2010

Pros and cons of apps for common New Year's resolutions

With about 400,000 apps available for Smartphones and news ones added daily, there is an app for almost everything, from losing weight to finding a job.

24 Dec 2010

Near-complete data sets from fruit fly and roundworm genomes

An Ontario researcher has played a key role in the development of a new resource that will help genomics researchers around the world find new ways to prevent and treat cancer.

24 Dec 2010

AMPK activates autophagy by activating ATG1 enzyme

Researchers at the Salk Institute for Biological Studies have discovered how AMPK, a metabolic master switch that springs into gear when cells run low on energy, revs up a cellular recycling program to free up essential molecular building blocks in times of need.

24 Dec 2010

Quercetin and resveratrol may play an important role in inflammation and insulin resistance

A study was carried out to examine the extent to which quercetin and trans-resveratrol (RSV) prevented inflammation or insulin resistance in primary cultures of human adipocytes treated with tumor necrosis factor-a (TNF-a)-an inflammatory cytokine elevated in the plasma and adipose tissue of obese, diabetic individuals. Cultures of human adipocytes were pretreated with quercetin and trans-RSV followed by treatment with TNF-a. Subsequently, gene and protein markers of inflammation and insulin resistance were measured.

24 Dec 2010

Scientists tweak gene to mimick heart-strengthening effects of endurance training in sedentary mice

By tweaking a single gene, scientists have mimicked in sedentary mice the heart-strengthening effects of two weeks of endurance training, according to a report from Dana-Farber Cancer Institute and Beth Israel Deaconess Medical Center (BIDMC).

24 Dec 2010

Sequestering GSK3 enzyme leads to stabilization of proteins in cells

The cell signaling pathway known as Wnt, commonly activated in cancers, causes internal membranes within a healthy cell to imprison an enzyme that is vital in degrading proteins, preventing the enzyme from doing its job and affecting the stability of many proteins within the cell, researchers at UCLA's Jonsson Comprehensive Cancer Center have found.

24 Dec 2010

American Regent initiates voluntary recall of Sodium Bicarbonate Injection, USP 7.5% and 8.4%

American Regent is conducting a nationwide voluntary recall to the consumer and user level of ALL unexpired lots of the following products: Sodium Bicarbonate Injection, USP, 7.5%, 44.6 mEq/50 mL, Single Dose Vial

24 Dec 2010

Paternal diet affects lipid metabolizing genes in offspring

Scientists at the University of Massachusetts Medical School and the University of Texas at Austin have uncovered evidence that environmental influences experienced by a father can be passed down to the next generation, "reprogramming" how genes function in offspring. A new study published this week in Cell shows that environmental cues-in this case, diet-influence genes in mammals from one generation to the next, evidence that until now has been sparse.

24 Dec 2010

Researchers study relationship between MITF, ATF2 in melanoma development

Melanoma is one of the least common types of skin cancer, but it is also the most deadly. Melanocytes (pigment-producing skin cells) lose the genetic regulatory mechanisms that normally limit their number, allowing them to divide and proliferate out of control. One such regulator, called MITF, controls an array of genes that influence melanocyte development, function and survival.

24 Dec 2010

Study shows vegetarian diet lowers blood, urine phosphorous levels

Phosphorous levels plummet in kidney disease patients who stick to a vegetarian diet, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology. The results suggest that eating vegetables rather than meat can help kidney disease patients avoid accumulating toxic levels of this mineral in their bodies.

24 Dec 2010

MCP-1 protein may contribute to failure of AV fistulas created for vascular access in dialysis patients

A protein implicated in the development of vascular diseases may also contribute to the failure of arteriovenous (AV) fistulas created for vascular access in dialysis patients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

23 Dec 2010

Catalogs of fruit fly and roundworm's functional genomic elements

Scientists today published catalogs of the fruit fly and roundworm's functional genomic elements: DNA sequences in the genome that carry the instructions and determine which genes are turned on and off at various times in different cells.

23 Dec 2010

Researchers discover recycling mechanism of signaling receptors

An international team of researchers led by Carnegie Mellon University's Manojkumar Puthenveedu has discovered the mechanism by which signaling receptors recycle, a critical piece in understanding signaling receptor function. Writing in the journal Cell, the team for the first time describes how a signaling receptor travels back to the cell membrane after it has been activated and internalized.

23 Dec 2010

Earlier diagnosis in Cowden syndrome patients predisposed to breast and kidney cancer

Researchers at Cleveland Clinic's Genomic Medicine Institute have revealed multiple genetic discoveries that may permit easier diagnosis and disease management for Cowden syndrome patients who are predisposed to breast and kidney cancer.

23 Dec 2010

Scientist discovers molecular switch controlling synthesis of ribosomes

A scientist from the Florida campus of The Scripps Research Institute has discovered a molecular switch that controls the synthesis of ribosomes. Ribosomes are the large machineries inside all living cells that produce proteins, the basic working units of any cell. These new findings offer a novel target for potential treatments for a range of diseases, including cancer.

23 Dec 2010

Key to long-term weight-loss success is finding unique individual level of carbohydrate tolerance

Recent media coverage suggests that the reported wedding diet of Carole Middleton, mother of future British princess Kate Middleton, is something brand new. Yet the Dukan Diet is just another variation of the Atkins Diet™, but with some nutritional recommendations that simply don't make sense or are guaranteed to fail.

23 Dec 2010

Discovery highlights potential to combat HIV/AIDS

Researchers at the University of Minnesota have discovered how HIV binds to and destroys a specific human antiviral protein called APOBEC3F. The results suggest that a simple chemical change can convert APOBEC3F to a more effective antiviral agent and that shielding of a common feature shared by related proteins may yield a similar outcome.

23 Dec 2010

Immunization with VLP vaccine results in functional, protective immune responses against RSV

Novavax, and scientists at the University of Massachusetts Medical School, led by Dr. Trudy Morrison, published in the January 2011 issue of The Journal of Virology, a report indicating that a novel virus-like particle vaccine candidate against respiratory syncytial virus (RSV) protects mice from a live virus challenge.

23 Dec 2010

G Protein News and Research

New findings reveal long-term influences of infant formula composition

Researchers develop microfluidic device to orient hundreds of embryos for research

Pros and cons of apps for common New Year's resolutions

Near-complete data sets from fruit fly and roundworm genomes

AMPK activates autophagy by activating ATG1 enzyme

Quercetin and resveratrol may play an important role in inflammation and insulin resistance

Scientists tweak gene to mimick heart-strengthening effects of endurance training in sedentary mice

Sequestering GSK3 enzyme leads to stabilization of proteins in cells

American Regent initiates voluntary recall of Sodium Bicarbonate Injection, USP 7.5% and 8.4%

Paternal diet affects lipid metabolizing genes in offspring

Researchers study relationship between MITF, ATF2 in melanoma development

Study shows vegetarian diet lowers blood, urine phosphorous levels

MCP-1 protein may contribute to failure of AV fistulas created for vascular access in dialysis patients

Catalogs of fruit fly and roundworm's functional genomic elements

Researchers discover recycling mechanism of signaling receptors

Earlier diagnosis in Cowden syndrome patients predisposed to breast and kidney cancer

Scientist discovers molecular switch controlling synthesis of ribosomes

Key to long-term weight-loss success is finding unique individual level of carbohydrate tolerance

Discovery highlights potential to combat HIV/AIDS

Immunization with VLP vaccine results in functional, protective immune responses against RSV

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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