Protein C News and Research

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Immune system directly links personality to long-term mortality risk, study reveals

Ground-breaking research led by University of Limerick has revealed for the first time that the immune system directly links personality to long-term risk of death.

17 Feb 2021

Nanotherapy shows potential for treating severe Crohn's disease

Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn's disease.

17 Feb 2021

Novel hydrogel slowly releases RNA nanovaccines to shrink tumors

Messenger RNA (mRNA) vaccines to prevent COVID-19 have made headlines around the world recently, but scientists have also been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer.

17 Feb 2021

Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

17 Feb 2021

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

A team of researchers used several assays, atomic force microscopy, and simulations to determine that the N501Y mutation in the virus’s receptor-binding domain (RBD) increased the interaction of the virus with the angiotensin-converting enzyme 2 (ACE2) receptor.

17 Feb 2021

SARS-CoV-2 nucleoprotein increases infectivity of spike-based pseudoviruses

In a recent study conducted at the Indian Institute of Science Education and Research, India, a team of scientists screened specific genes of SARS-CoV-2 to identify factors that may contribute to viral infectivity.

17 Feb 2021

The origin of SARS-CoV-2 furin cleavage site remains a mystery

A new study discusses the origin of the furin cleavage site on the SARS-CoV-2 spike protein, which is responsible for the virus’s relatively high infectivity compared to relatives in the betacoronavirus subgenus.

17 Feb 2021

What are the main food safety concerns associated with the COVID-19 pandemic?

A new study deals with the main food safety concerns associated with the COVID-19 pandemic.

17 Feb 2021

China's SARS and SARS-CoV-2 outbreak management in comparative perspective

A new study compares the current SARS-CoV-2 outbreak with the earlier SARS-CoV epidemic to understand the best way to respond to it sensitively and flexibly. This involves early detection, using multiple screening tests, followed by management of the clinical features as required, in order to prevent disease-related injury.

17 Feb 2021

Researchers identify molecular link between inflammatory signaling molecule and a main oncogene

A team of MedUni Vienna researchers led by Johannes A. Schmid at the Center for Physiology and Pharmacology, Institute of Vascular Biology and Thrombosis Research, has managed to identify a previously unknown molecular connection between an inflammatory signaling molecule and one of the main oncogenes.

17 Feb 2021

Probiotics may be beneficial in COVID-19 treatment

A new study explores the role of common probiotics in managing the disease, which could prove to be of great value, given the emergence of new variants and the broad spectrum of clinical disease in COVID-19.

17 Feb 2021

Understanding stroke and heart disease in women remains a major research priority

Understanding the sex differences in cardiovascular disease presentation and outcomes remains a major research priority demonstrated by the record number of submissions for this year's Go Red for Women® special issue of the American Heart Association's flagship journal Circulation, published online today.

17 Feb 2021

Lewy body dementia may share similar genetic profiles with Alzheimer's disease

In a study led by National Institutes of Health (NIH) researchers, scientists found that five genes may play a critical role in determining whether a person will suffer from Lewy body dementia, a devastating disorder that riddles the brain with clumps of abnormal protein deposits called Lewy bodies.

17 Feb 2021

Key protein in cholera-causing bacteria enables them to adapt to temperature changes

Scientists have discovered an essential protein in cholera-causing bacteria that allows them to adapt to changes in temperature, according to a study published today in eLife.

17 Feb 2021

Composition of protein solution plays a decisive role in cataract formation

Cataracts are the most common eye ailment in humans. However, the exact processes leading to this condition are not fully understood.

17 Feb 2021

Nsp1 protein could provide new treatments for COVID-19

A study that identifies how a coronavirus protein called Nsp1 blocks the activity of genes that promote viral replication provides hope for new COVID-19 treatments.

16 Feb 2021

Changes to gut microbiome help melanoma patients respond to immunotherapy

Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients' gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.

16 Feb 2021

Detection of emerging SARS-CoV-2 variant in New York

Researchers at the California Institute of Technology in Pasadena have developed a software tool called "Variant Database" that has detected an emerging lineage of severe acute respiratory coronavirus 2 (SARS-CoV-2) isolates in New York.

16 Feb 2021

Mice study suggests novel approach to treat a type of common glioma

Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health, researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas--a type of slow-growing glioma--and found tumor regression in 60 percent of the mice treated.

16 Feb 2021

Biodegradable microcapsules loaded with nerve growth factor can guide neuronal development

Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in vitro experiment.

16 Feb 2021