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Common genetic defect in prostate cancer associated with worse prognosis

Like security screening to make sure nothing harmful makes its way into a crowded area, cells in the human body use checkpoints to control their growth and prevent harmful mutations from making their way into new cell populations and causing trouble.

9 Jan 2020

Scientists identify 'modifier gene' that determines severity of inherited kidney disease

Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalised treatments.

9 Jan 2020

Scientists find way to combine two main coding languages into single 'bilingual' molecule

The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes underlying all of life.

9 Jan 2020

Targeting VEGFA signaling in the epidermis can prevent psoriasis development

Psoriasis is a frequent skin inflammatory disorder affecting 3% of the population. Psoriasis is characterized by hyperproliferation and defect of epidermal differentiation, leading to the scaly appearance of the skin. The psoriasis skin also presents an increase in blood vessels, leading to the redness of the skin lesions and is associated with immune infiltration.

9 Jan 2020

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

Researchers at Osaka University have developed a computer method that uses magnetic resonance imaging (MRI) and machine learning to rapidly forecast genetic mutations in glioma tumors, which occur in the brain or spine. The work may help glioma patients to receive more suitable treatment faster, giving better outcomes.

9 Jan 2020

Smoking dormant HIV virus out into the open to develop a cure

Ever since antiretroviral treatments against HIV infection were introduced in 1996, scientists have eagerly been hunting for a cure for the disease.

9 Jan 2020

Poor early life environment leaves permanent mark on adult brain

A severely deprived child may never really recover from the impact of deprivation early in life, finds a new study.

9 Jan 2020

Researchers discover genes that could explain the Browning ability of white fat

Our fat cells, technically referred to as adipocytes, play an essential role in regulating energy balance in our body.

9 Jan 2020

PCORI announces new research funding opportunities to improve patient-centered outcomes

Following congressional reauthorization of its funding in December 2019, the Patient-Centered Outcomes Research Institute (PCORI) began accepting new proposals for research designed to help patients and those who care for them to weigh their options and make better-informed healthcare decisions.

9 Jan 2020

Researchers identify synergistic cellular pathways that considerably amplify lifespan

Scientists at the MDI Biological Laboratory, in collaboration with scientists from the Buck Institute for Research on Aging in Novato, Calif., and Nanjing University in China, have identified synergistic cellular pathways for longevity that amplify lifespan fivefold in C. elegans, a nematode worm used as a model in aging research.

9 Jan 2020

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Pathios Therapeutics Limited, an innovative biotech company focused on the development of first-in-class therapies for autoimmune diseases and cancer, today announced a US$8.8M Series A financing round with leading international healthcare investors Canaan and Australia’s Medical Research Commercialization Fund managed by Brandon Capital.

9 Jan 2020

Diabetes drug could be repurposed as new treatment to prevent miscarriage

A drug designed to tackle diabetes could also be repurposed as the first treatment to prevent miscarriage by targeting the lining of the womb itself, according to a clinical trial led by the University of Warwick.

9 Jan 2020

Researchers identify new mechanism associated with p53 mutation

More than half of cancer cases worldwide are associated with genetic mutations in p53, the protein responsible for protecting DNA from changes that can lead to cancer.

9 Jan 2020

SVC112 molecule acts specifically against head and neck cancer stem cells

The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds.

8 Jan 2020

Post-mortem genetic testing used to find underlying cause of sudden deaths in Amish families

Researchers used post-mortem genetic testing to find the underlying cause of multiple sudden deaths in young people and sudden cardiac arrests in two large Amish families.

8 Jan 2020

Researchers use single cell genome sequencing to study malaria transmission

New technology employing single cell genome sequencing of the parasite that causes malaria has yielded some surprising results and helps pave the way for possible new intervention strategies for this deadly infectious disease, according to Texas Biomedical Research Institute Assistant Professor Ian Cheeseman, Ph.D. Dr. Cheeseman was Principal Investigator of a three-year study published in the January 2020 edition of Cell Host & Microbe, a high-impact peer-reviewed publication.

8 Jan 2020

Cystic fibrosis carriers have higher risk for all CF-related conditions

Conventional wisdom says that having just one mutated copy of the cystic fibrosis gene has no effects on a person's health--the disease occurs when both copies of the gene are mutated. But a new study from the University of Iowa suggests that may not be the case.

8 Jan 2020

Genetic News and Research

Common genetic defect in prostate cancer associated with worse prognosis

Scientists identify 'modifier gene' that determines severity of inherited kidney disease

Scientists find way to combine two main coding languages into single 'bilingual' molecule

Targeting VEGFA signaling in the epidermis can prevent psoriasis development

New method uses MRI, machine learning to forecast genetic mutations in glioma tumors

Smoking dormant HIV virus out into the open to develop a cure

Poor early life environment leaves permanent mark on adult brain

Researchers discover genes that could explain the Browning ability of white fat

PCORI announces new research funding opportunities to improve patient-centered outcomes

Researchers identify synergistic cellular pathways that considerably amplify lifespan

Pathios appoints Stuart Hughes as CEO and announces US$8.8M Series A financing round

Diabetes drug could be repurposed as new treatment to prevent miscarriage

Researchers identify new mechanism associated with p53 mutation

SVC112 molecule acts specifically against head and neck cancer stem cells

Post-mortem genetic testing used to find underlying cause of sudden deaths in Amish families

Researchers use single cell genome sequencing to study malaria transmission

Cystic fibrosis carriers have higher risk for all CF-related conditions

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Research adds definitive evidence about how the body's earliest immune cells are formed

Study finds no significant link between using talc and ovarian cancer risk

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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