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Discovery of novel genetic markers linked to increased risk of heart attack

An international team of researchers including scientists of Helmholtz Zentrum München has succeeded in identifying new gene variants associated with an increased risk for myocardial infarction (MI), or heart attack.

17 Feb 2009

Braconid parasite wasps have practiced gene therapy for a hundred million years

Braconid parasite wasps and their caterpillar hosts form a unique host-parasite model: the wasps lay their eggs inside the caterpillars and simultaneously inject some viral particles to get around the host's defenses and control its physiology.

17 Feb 2009

Researcher presents evolutionary history of modern humans in Africa

Sarah A. Tishkoff, PhD, David and Lyn Silfen University Associate Professor, will present "Evolutionary History of Modern Humans in Africa," at the 2009 American Association for the Advancement of Science (AAAS) annual meeting in Chicago, as a part of the Sunday, February 15th session, "Studying Vertebrate Genomes: Reading Evolution's Notebooks."

16 Feb 2009

Jumping genes play significant role in gene regulatory networks

Research performed in the Center for Biomolecular Science & Engineering (CBSE) at the University of California, Santa Cruz, suggests that mobile repetitive elements--also known as transposons or "jumping genes"--do indeed affect the evolution of gene regulatory networks.

16 Feb 2009

Novel blood test for hepatitis C

A novel blood test could bring a breakthrough in the battle against the dangerous hepatitis-C virus.

15 Feb 2009

From the works of Shakespeare to the genomes of viruses

What does uncovering the true authorship of plays attributed to Shakespeare have to do with identifying our genetic ancestors or classifying new life forms?

11 Feb 2009

Volcanoes in the genome, blowing out pieces of DNA

Roughly 10 million years ago, a major genetic change occurred in a common ancestor of gorillas, chimpanzees, and humans.

11 Feb 2009

New understanding of how leukemia develops

In a collaborative study published Feb. 9, 2009, in the Proceedings of the National Academy of Sciences (PNAS), scientists performed a genome-wide expression analysis comparing highly enriched normal blood stem cells and leukemic stem cells, and identified several new pathways that have a key role in cancer development.

9 Feb 2009

Camouflaging of viral DNA could be crucial step in progression of cancers

An estimated 15% of cancer cases can be linked to a viral infection, however the biological changes that cause some asymptomatic carriers of a virus to develop full-blown tumors are not well understood.

9 Feb 2009

Study identifies gene variants associated with early-onset myocardial infarction

The largest study ever completed of genetic factors associated with heart attacks has identified nine genetic regions - three not previously described - that appear to increase the risk for early-onset myocardial infarction.

8 Feb 2009

FDA approves orphan drug ATryn anticoagulant

The U.S. Food and Drug Administration has issued its first approval for a biological product produced by genetically engineered (GE) animals.

8 Feb 2009

Breakthrough in thyroid cancer may enable more targeted risk assessment and earlier intervention

Scientists at deCODE genetics presented the discovery of two single letter variations in the sequence of the human genome (SNPs) conferring substantial increased risk of thyroid cancer.

8 Feb 2009

Extra copies of LIS1 gene carry extra risk

Is more of a good thing better? A gene known as LIS1 is crucial for ensuring the proper placement of neurons in the developing brain.

5 Feb 2009

Scientists discover missing link in the way cells protect themselves against cancer

Cancer Research UK scientists have discovered a missing link in the way cells protect themselves against cancer, according to research published in Genes & Development.

5 Feb 2009

Novel gene may cause restless legs syndrome in a large family

In 2005, a woman who had trouble sleeping asked Siong-Chi Lin, M.D., for help. Dr. Lin, a sleep disorders specialist at the Mayo Clinic campus in Florida, diagnosed restless legs syndrome.

3 Feb 2009

Scientists unlock secrets of gene regulatory networks

A quartet of studies by researchers at the California Institute of Technology (Caltech) highlight a special feature on gene regulatory networks recently published in the Proceedings of the National Academy of Sciences ( PNAS ).

3 Feb 2009

Discovery fleshes out metabolism of key environmental and energy bacteria

An international collaboration of researchers has discovered a new enzyme in a species of bacteria with potential environmental cleanup and energy roles.

2 Feb 2009

New genetic clues on molecular evolution of Q fever pathogen

Scientists from the National Institute of Allergy and Infectious Diseases, Texas A&M Health Center, and the Virginia Bioinformatics Institute at Virginia Tech have uncovered genetic clues about why some strains of the pathogen Coxiella burnetii are more virulent than others.

2 Feb 2009

Single gene lets bacteria jump from host to host

All life - plants, animals, people - depends on peaceful coexistence with a swarm of microbial life that performs vital services from helping to convert food to energy to protection from disease.

2 Feb 2009

Discovery of new class of non-protein coding genes in mammals with key functions

A research team at the Broad Institute of Harvard and MIT and Beth Israel Deaconess Medical Center has uncovered a vast new class of previously unrecognized mammalian genes that do not encode proteins, but instead function as long RNA molecules.

2 Feb 2009