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Nighttime intensivists have no effect on ICU length of stay, find researchers

With little evidence to guide them, many hospital intensive care units have been employing critical care physicians at night with the notion it would improve patients' outcomes. However, new results from a one-year randomized trial from researchers at Penn Medicine involving nearly 1,600 patients admitted to the Hospital of the University Pennsylvania Medical ICU suggest otherwise: Having a nighttime intensivist had no clear benefit on length of stay or mortality for these patients, not even patients admitted at night or those with the most critical illnesses at the time of admission.

21 May 2013

Childhood maltreatment linked to increased risk of obesity in adult life

Children who have suffered maltreatment are 36% more likely to be obese in adulthood compared to non-maltreated children, according to a new study by King's College London. The authors estimate that the prevention or effective treatment of 7 cases of child maltreatment could avoid 1 case of adult obesity.

21 May 2013

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression in the weeks after giving birth, and an opportunity to intervene before symptoms become debilitating.

21 May 2013

Biogen Idec seeks FDA BLA approval for PLEGRIDY to treat multiple sclerosis

Today Biogen Idec announced it has submitted a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for approval of PLEGRIDY (peginterferon beta-1a), the company's pegylated subcutaneous injectable candidate for relapsing forms of multiple sclerosis (RMS).

21 May 2013

State rejections of Medicaid expansion likely to widen health disparities

The Los Angeles Times reports that states opting against expanded eligibility -- among them, some of the nation's unhealthiest -- could fall even further behind as the Affordable Care Act is implemented. News outlets also offer reports from Arizona, Michigan, Wisconsin, Ohio, California, Florida and Virginia.

21 May 2013

LBDA launches nationwide Lewy body dementia awareness movement

This year marks the tenth anniversary of the Lewy Body Dementia Association (LBDA), the only nonprofit organization in the United States dedicated to supporting LBD families through outreach, education and research.

21 May 2013

Blind people have potential to use echolocation to locate objects, new research shows

New research from the University of Southampton has shown that blind and visually impaired people have the potential to use echolocation, similar to that used by bats and dolphins, to determine the location of an object.

21 May 2013

UIC researchers to study gender differences in how the heart uses and stores fat

Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat -- its main energy source -- and how changes in fat metabolism play a role in heart disease, under a new $2 million, 4-year grant from the National Heart, Lung and Blood Institute.

21 May 2013

Viewpoints: Sebelius' 'ethical line'; As tricky phase of health law approaches, concerns about exchanges opening on time

One of the biggest questions hanging over the health-care system is how many young Americans will sign up for coverage once the Affordable Care Act begins to phase in this October. If too few buy insurance on the markets that the government is creating, insurance companies would be stuck covering primarily the old and the sick. They would have to pay out more per customer.

21 May 2013

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day.

21 May 2013

Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Disruption of brain developmental processes caused by premature birth can affect cognitive function

Researchers from King's College London have for the first time used a novel form of MRI to identify crucial developmental processes in the brain that are vulnerable to the effects of premature birth.

21 May 2013

IRS scandal, HHS fundraising stir the health law political pot

The Obama administration's efforts to raise money from private sources for the health law have led some likely donors to become "skittish." Meanwhile, as GOP lawmakers seek to link the Internal Revenue Service issues to the health law, media outlets examine the IRS's reach in this regard.

21 May 2013

Groundbreaking germ-fighting vaccine research to be presented at National Biotechnology Conference

A novel vaccine study from South Dakota State University will headline the groundbreaking research that will be unveiled at the American Association of Pharmaceutical Scientists' National Biotechnology Conference.

21 May 2013

Research explores pharmaceutical advances for IBS, hepatitis C

Research presented at Digestive Disease Week explores pharmaceutical advances for treating irritable bowel syndrome with diarrhea and hepatitis C.

21 May 2013

Health law's insurance exchanges are not mirror image of Mass. version

Some of the state's features that advocates say helped consumers make their insurance-purchasing decisions were not included in the the federal health law.

21 May 2013

New diagnostic test for lymphatic filariasis

A new diagnostic test for a worm infection that can lead to severe enlargement and deformities of the legs and genitals is far more sensitive than the currently used test, according to results of a field study in Liberia, in West Africa, where the infection is endemic.

21 May 2013

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

AbbVie announced today the initiation of a Phase 3 clinical study called SONAR (Study Of Diabetic Nephropathy with Atrasentan) to assess the effects of the investigational compound atrasentan - when added to standard of care - on progression of kidney disease in patients with stage 2 to 4 chronic kidney disease and type 2 diabetes.

21 May 2013

CBO: Obama's budget would reduce Medicare spending by $364B

The Congressional Budget Office estimated Friday that President Obama's budget would reduce Medicare spending by $364 billion over the next decade and would reduce future budget deficits. The White House and Congress will likely soon need to work on a long-term budget solution as the nation again approaches its debt limit.

21 May 2013

People exposed to wood and tobacco smoke are at greater risk for developing COPD

People who are consistently exposed to both wood smoke and tobacco smoke are at a greater risk for developing chronic obstructive pulmonary disease and for experiencing more frequent and severe symptoms of the disease, as well as more severe airflow obstruction, than those who are exposed to only one type of smoke, according to the results of a new population-based study conducted by researchers in Colombia.

21 May 2013

Research News and Research

Nighttime intensivists have no effect on ICU length of stay, find researchers

Childhood maltreatment linked to increased risk of obesity in adult life

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

Biogen Idec seeks FDA BLA approval for PLEGRIDY to treat multiple sclerosis

State rejections of Medicaid expansion likely to widen health disparities

LBDA launches nationwide Lewy body dementia awareness movement

Blind people have potential to use echolocation to locate objects, new research shows

UIC researchers to study gender differences in how the heart uses and stores fat

Viewpoints: Sebelius' 'ethical line'; As tricky phase of health law approaches, concerns about exchanges opening on time

Researchers say that receiving cancer radiation therapy late in the day may minimize hair loss

Researchers develop new mouse model to discover gene pathways that drive MPNST

Disruption of brain developmental processes caused by premature birth can affect cognitive function

IRS scandal, HHS fundraising stir the health law political pot

Groundbreaking germ-fighting vaccine research to be presented at National Biotechnology Conference

Research explores pharmaceutical advances for IBS, hepatitis C

Health law's insurance exchanges are not mirror image of Mass. version

New diagnostic test for lymphatic filariasis

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

CBO: Obama's budget would reduce Medicare spending by $364B

People exposed to wood and tobacco smoke are at greater risk for developing COPD

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