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Heart attack patients who follow more medical advice have greater long-term survival

Patients who followed more medical advice after a heart attack were more likely to survive years after their heart attack.

5 Mar 2020

Beating heart muscle tissues to be sent up to the microgravity environment of ISS

Launching no earlier than March 6 at 11:50 PM EST, the Johns Hopkins University will send heart muscle tissues, contained in a specially-designed tissue chip the size of a small cellphone, up to the microgravity environment of the International Space Station for one month of observation.

5 Mar 2020

Researchers identify mechanism that explains why women experience more pain than men

Imagine taking a pill to control your pain and, instead, the medication actually increases the pain you feel.

5 Mar 2020

New collapsible basket technology has big advantages for drug discovery, personalized medicine

A drug discovery scientist typically screens up to 10,000 compounds in the early stages of developing one FDA approved drug. During this high-throughput screening, candidate compounds are initially tested on cell and tissue samples.

4 Mar 2020

Respiratory antivirals and risk to breastfeeding women

Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.

4 Mar 2020

Smartphone users have more headaches, find less relief from the medication

A new study published in the March 2020 issue of the journal Neurology Clinical Practice reports that smartphone use by people who have headaches is associated with greater use of medication but less relief, compared to those who do not use smartphones when they have headaches. This does not prove that smartphone use is responsible for the increased need for drugs or the relative intractability of the headaches, but shows a linkage.

4 Mar 2020

Type 2 diabetes mellitus responds to weight loss surgery

Type 2 diabetes mellitus (T2DM) is a metabolic condition with close links to weight gain. Since weight loss is a proven way to control T2DM, it is to be expected that surgeries to achieve weight loss should result in better regulation of blood glucose levels.

4 Mar 2020

Nearly $4 million to fund drug discovery research for Alzheimer's, other dementia

The Alzheimer's Association and the Rainwater Charitable Foundation have joined forces again to fund drug discovery research towards finding therapies for Alzheimer's disease, frontotemporal degeneration, and other tauopathies.

4 Mar 2020

Biomaterials could soon create tissue like blood vessel structures

A group of researchers led by Professor Alvaro Mata from the University of Nottingham, along with others from Queen Mary University London, has successfully created a biomaterial that could be used for the creation of tissues that could form blood vessels. The study titled, “Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices,” was published in the latest issue of the journal Nature Communications.

4 Mar 2020

New report reveals damaging impact of poverty and exploitation on children

The damaging impact of poverty on children and their families and the growing problem of exploitation are revealed in a new report by researchers at the University of East Anglia and University of Warwick.

4 Mar 2020

Novel compounds show promise as potent new treatment for malaria

A novel class of antimalarial compounds that can effectively kill malaria parasites has been developed by Australian and US researchers.

4 Mar 2020

New experimental platform for cancer diagnostics, prognoses and testing drugs

Parts of tumor tissue, which is normally discarded in cancer surgery, bear information about the disease. So far, as studies at the University of Gothenburg show, this has been unexploited.

4 Mar 2020

A new, promising method for developing drugs that target, block macropinocytosis

With drug resistance a major challenge in the fight against cancer, a discovery by University of California, Irvine biologists could offer new approaches to overcoming the obstacle.

3 Mar 2020

Drug prices beat inflation all the way even with discounts

A new study published in the journal JAMA in March 2020 shows how prescription drug prices are rising faster than the rate of inflation. The decade-long trend reflects a threefold higher rise in brand-name drug prices compared to inflation if all drugs are lumped together.

3 Mar 2020

Novel drug to arrest antibiotic resistance by preventing micro-evolution

Desperate times need desperate measures. Accordingly, scientists, today published a new study in the journal Cell Host and Microbe in March 2020, showing that drugs that prevent the acquisition of DNA-borne antibiotic resistance traits from their surroundings by bacteria can stop mice from becoming resistant to the action of the antibiotics.

3 Mar 2020

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

Big Pharma more profitable than most other large public firms

A large study published in the journal JAMA in March 2020 reports that large pharmaceutical companies make a much larger profit from their products than other large public companies. This is important because it indicates the potential to reduce drug prices while sustaining competitive and innovative drug development and marketing.

3 Mar 2020

The research and development costs of a new drug

Many recent studies have focused on how much it costs to bring a new drug to market in the light of increasing drug prices. Estimates range from $314 million to $2.8 billion. Most of this was based on proprietary data and was, therefore, not verifiable independently, attracting much criticism.

3 Mar 2020

New step towards the development of non-addictive painkillers

Opioid-containing painkillers are virtually indispensable in clinical practice and are typically used in postoperative patients and patients undergoing cancer treatment.

3 Mar 2020

New method maps 3D forces exerted by tiny cell clusters

A team of researchers has developed a new technique to map the three-dimensional forces that clusters of human cells exert on their surrounding environment. The method could potentially help scientists better understand how tissue forms, how wounds heal or how tumors spread.

3 Mar 2020