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Scientists decipher the molecular blueprint for important receptor

In order for a drug to be effective at the right places in the body, it helps if scientists can predict as accurately as possible how the molecules of that drug will interact with human cells.

10 Feb 2021

Exposure to seasonal coronaviruses does not produce antibodies that protect against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2021

Second dose of Pfizer-BioNTech COVID-19 vaccine may not benefit previously infected individuals

Researchers at the NYU Grossman School of Medicine have shown that a second dose of the Pfizer-BioNTech BNT162b2 vaccine may not offer any additional protection against coronavirus disease 2019 (COVID-19) over one dose among individuals previously infected with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

10 Feb 2021

Substrain of SARS-CoV-2 variant in UK may resist antibody neutralization

Researchers at the Polish Academy of Sciences in Warsaw have identified a substrain of the recently emerged B.1.1.7 variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may confer resistance to antibody neutralization.

10 Feb 2021

Freiburg immunologists decipher anti-cancer drug's mode of operation

Rituximab, an anti-cancer drug targeting the membrane protein CD20, was the first approved therapeutic antibody against B tumor cells. Immunologists at the University of Freiburg have now solved a mystery about how it works.

10 Feb 2021

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Researchers have measured the galectin-3 levels in the sera of hospitalized patients. They found initial high levels indicate patients will become severely ill, suggesting it could be used as a predictor of severe disease.

10 Feb 2021

Study shows local topological free energy as determinant of SARS-CoV-2 spike stability

A recent study conducted by US scientists has demonstrated that the distribution of local topological free energy along the spike protein domains of SARS-CoV-2 is associated with their activity in protein rearrangement.

10 Feb 2021

Some COVID-19 patients experience persistent chronic fatigue six months after infection, finds study

Scientists from Germany recently revealed that almost 50% of patients present with moderate to severe chronic fatigue syndrome six months after SARS-CoV-2 infection.

10 Feb 2021

Taking Advantage of Measuring Molecular Collisional Cross-Sections in Pharma

News-Medical talks to Mike Greig, Director of Pharma at Bruker, about why measuring collisional cross-sections is beneficial to developing new drugs.

From Bruker Daltonics 10 Feb 2021

Could a SARS-CoV-2 accessory protein be responsible for certain COVID-19 symptoms?

Researchers highlight the potential causes of some COVID-19 symptoms. Early in the pandemic, the hallmark symptoms of COVID-19 include cough, fever, and shortness of breath. As the pandemic has evolved, more symptoms have emerged, such as loss of smell and taste, headache, intestinal issues, and abdominal pains.

10 Feb 2021

Study unravels function of 'mystery protein' that kills brain cells of people with Parkinson's

A study published in Nature Communications today (Wednesday 10 February) presents compelling new evidence about what a key protein called alpha-synuclein actually does in neurons in the brain.

10 Feb 2021

Polyclonal SARS-CoV-2 antibody shows potent neutralizing activity in vitro

Researchers shows a fully human immunoglobulin (IgG) that potently inhibits SARS-CoV-2 infection.

10 Feb 2021

Scientists are exploring new possibilities to make more effective COVID-19 vaccines

Advances in the fields of biomaterials and nanotechnology could lead to big breakthroughs in the fight against dangerous viruses like the novel coronavirus that causes COVID-19.

10 Feb 2021

FDA issues EUA for bamlanivimab and etesevimab for COVID-19 treatment

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for bamlanivimab and etesevimab administered together for the treatment of mild to moderate COVID-19 in adults and pediatric patients (12 years of age or older weighing at least 40 kilograms [about 88 pounds]) who test positive for SARS-CoV-2 and who are at high risk for progressing to severe COVID-19.

10 Feb 2021

Cellular survival after radiation exposure depends on the specific protein behavior

Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others.

10 Feb 2021

Scientists urge health agencies to invest in COVID-19 vaccine development to prevent next pandemic

As new COVID-19 variants begin to throw vaccine efficacy in question, two leading scientists are calling for health agencies to invest in the development of vaccines that would be broadly effective against many different variants and strains of potential pandemic viruses.

10 Feb 2021

Modified CRISPR/Cas9 complex targets specific histones

Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle.

9 Feb 2021

Both mRNA vaccines protect against emerging variants of SARS-CoV-2

Researchers in the United States and Canada have conducted a study showing that just a single dose of either the Pfizer-BioNTech or Moderna vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is likely to protect against emerging variants.

9 Feb 2021

A new approach for detecting and treating two rare pediatric diseases before birth

Scientists have devised a new approach for detecting and potentially heading off the effects of two rare pediatric diseases before birth.

9 Feb 2021

New molecular tool can be used to study single synapses of neurons

Neurons are the primary cells of the nervous system, and the signals that are transmitted between them are responsible for all our actions and our cognitive ability.

9 Feb 2021

Protein C News and Research

Scientists decipher the molecular blueprint for important receptor

Exposure to seasonal coronaviruses does not produce antibodies that protect against SARS-CoV-2

Second dose of Pfizer-BioNTech COVID-19 vaccine may not benefit previously infected individuals

Substrain of SARS-CoV-2 variant in UK may resist antibody neutralization

Freiburg immunologists decipher anti-cancer drug's mode of operation

Could Galectin-3 be a potential biomarker to help identify severe COVID-19 early?

Study shows local topological free energy as determinant of SARS-CoV-2 spike stability

Some COVID-19 patients experience persistent chronic fatigue six months after infection, finds study

Taking Advantage of Measuring Molecular Collisional Cross-Sections in Pharma

Could a SARS-CoV-2 accessory protein be responsible for certain COVID-19 symptoms?

Study unravels function of 'mystery protein' that kills brain cells of people with Parkinson's

Polyclonal SARS-CoV-2 antibody shows potent neutralizing activity in vitro

Scientists are exploring new possibilities to make more effective COVID-19 vaccines

FDA issues EUA for bamlanivimab and etesevimab for COVID-19 treatment

Cellular survival after radiation exposure depends on the specific protein behavior

Scientists urge health agencies to invest in COVID-19 vaccine development to prevent next pandemic

Modified CRISPR/Cas9 complex targets specific histones

Both mRNA vaccines protect against emerging variants of SARS-CoV-2

A new approach for detecting and treating two rare pediatric diseases before birth

New molecular tool can be used to study single synapses of neurons

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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