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Largest hepatitis-C U.S. study defines optimal therapy

Final results of the WIN-R trial,[1] the largest hepatitis C study conducted in U.S. patients, showed that weight-based REBETOL (ribavirin, USP) in combination therapy with PEG-INTRON (peginterferon alfa-2b) achieved significantly higher rates of sustained virologic response (SVR)[2] and lower rates of relapse compared to the combination therapy using a flat dose of ribavirin.

14 Nov 2005

Hospital liver transplant program suspended after 32 die waiting

Following reports in the media that a Southern California hospital had suspended its liver transplant program and had turned down scores of donor organs while 32 patients awaiting transplants had died, the facility has had it's certification of the liver transplant program revoked.

14 Nov 2005

Role of statin therapy in patients with heart failure

An advanced study launched at Yale School of Medicine is evaluating the role of statin therapy in patients with heart failure, one of the leading causes of hospitalization in people over age 65.

14 Nov 2005

Molecular origins of diabetes

An unexpected twist to a discovery reported just two months ago may significantly improve our understanding about the molecular origins of diabetes.

14 Nov 2005

How protein-enriched meals decrease hunger and reduce eating

Researchers have uncovered new evidence to explain the observation that diets rich in protein stunt the appetite, according to a report in the November Cell Metabolism.

13 Nov 2005

Statins reduce the risk of stroke after carotid artery endarterectomy

Carotid artery endarterectomy (CEA) is the most commonly performed operation to prevent stroke in the United States. However, the operation itself carries a small risk of stroke.

13 Nov 2005

Anabolic steroids help people with HIV put on weight and muscle mass

People with HIV who are treated with anabolic steroids to prevent AIDS wasting may realize modest gains in weight and muscle mass, a new review shows.

10 Nov 2005

Scientists identify molecular link between body fat and blood lipids

Scientists from Wageningen University in the Netherlands have discovered that a factor released from body fat, which they call Fasting-Induced Adipose Factor or FIAF, has a major impact on blood levels of HDL and triglycerides in mice.

10 Nov 2005

Doctor facing manslaughter charges in Australia sparks calls for overhaul of U.S. regulations

An Indian-born, American-trained surgeon who is facing possible manslaughter charges in Australia, and nicknamed "Dr Death" has sparked calls for an overhaul of health regulations and a review of malpractice suits in his U.S. home state of Oregon.

8 Nov 2005

Public health service to fund live liver transplants

An announcement that new organ transplant technology will now allow adult patients to receive liver transplants from a living relative for the first time on the NHS, marks a new era in public health services.

8 Nov 2005

HIV-positive patients have shorter survival periods while awaiting liver transplants

A new study on HIV-positive patients eligible for liver transplants found that their survival while waiting for a transplant is significantly shorter than patients who are HIV-negative.

7 Nov 2005

Expert highlights public health problem posed by colorectal cancer

Colorectal cancer is a significant public health problem for which differing treatment regimes hold different benefits in associated efficacy, safety and tolerability, according to study findings showcased at the 13th European Cancer Conference (ECCO).

3 Nov 2005

Largest study to date on risk factors associated with primary biliary cirrhosis

A case-control study of more than 2000 people has identified a number of factors that may induce primary biliary cirrhosis (PBC) in genetically susceptible individuals. These include a history of urinary tract infections, hormone replacement therapy, tobacco use, and nail polish use.

3 Nov 2005

Accumulation of fat in the liver linked to hypertension

The accumulation of fat in the liver, or "fatty liver," resulting from accumulation of central body fat, and perhaps not alcohol consumption, may represent an important underlying mechanism for the association between liver enzymes and hypertension.

3 Nov 2005

Stem cells appear to play a role in repairing organs

Not least because undifferentiated cells with features typical of stem cells are being increasingly found in organs like the liver, brain, and muscles, scientists are beginning to assume that these cells play a role in repairing organs.

3 Nov 2005

Socioeconomic status determines life expectancy in HIV patients

HIV patients with a low socioeconomic status are likelier to die much more often than patients with higher levels of wealth and education, a new UCLA study has found.

3 Nov 2005

Interferon combined with ribavirin treatment is effective for children with chronic Hepatitis C virus

Nearly half of 118 children with chronic Hepatitis C virus (HCV) treated with a combination of interferon-alpha-2b and an optimized dose of ribavirin achieved sustained viral response, and side effects were generally mild.

3 Nov 2005

Role of alpha tocopherol associated protein in prostate cancer

Researchers have identified a protein that disrupts an important signaling pathway in prostate cancer cells and suppresses growth of the cancer.

1 Nov 2005

Functional diffusion map to help predict brain tumor outcomes

A special type of MRI scan that measures the movement of water molecules through the brain can help doctors determine halfway through treatment whether it will successfully shrink the tumor or a patient's cancer will continue to grow, a new study shows.

1 Nov 2005

Unique approach to enhance the immune system in patients with breast or colorectal cancer

The study uses a potent immune-enhancing gene delivered directly into the cancer cells to make them look foreign to the body's immune system, which will then attack and destroy the cancer.

1 Nov 2005